Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
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Query: UMLS:C0017168 (
gastroesophageal reflux disease
)
11,783
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
The manifestations of
gastroesophageal reflux disease
(
GERD
) have been recently classified into either esophageal or extra-esophageal syndromes. Clinical history, questionnaire data and response to antisecretory therapy are insufficient to make a conclusive diagnosis of
GERD
. Endoscopy had a low sensitivity. Recently, the availability of multichannel intraluminal impedance and pH-monitoring (MII-pH) has modified the diagnostic approach towards atypical manifestations of
GERD
. There is a rising consensus that this technique should be considered as the gold standard for
GERD
diagnosis. Gastrin 17 (G-17) has been proposed as a non-invasive marker of
GERD
, due to the negative feedback between acid and the hormone.
G17
levels seem able to identify patients with acid and non-acid reflux.
...
PMID:Diagnosis of GERD in typical and atypical manifestations. 3056 15
