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Query: UMLS:C0017168 (gastroesophageal reflux disease)
 11,783 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The purpose of this study was to present the actual possibilities of bronchial asthma exacerbation control. The role of viral infection, especially, human metapneumovirus infection may be a leading cause of disease exacerbation in children population. Prevalence of gastroesophageal reflux had been detected in 24% of asthmatic patients, in some cases as a cause of asthma exacerbation. Glucocorticosteroid therapy is accepted as cardinal in asthma exacerbation, but some adverse effects create a control limit.
Pol Merkur Lekarski 2004 May
PMID:[Treatment of bronchial asthma exacerbation]. 1552 10

Gastroesophageal reflux disease (GERD) is a widespread morbid condition that adversely affects quality of life and results in great utilization of healthcare resources. Recently medical therapy has improved with the introduction of the proton pump inhibitors, but patients must take medicine rather indefinitely often on a daily basis. Surgical therapy with the application of laparoscopic fundoplication has improved too, but still is associated with invasiveness and morbidity. Now third option has emerged--endoscopic antireflux procedures. Three novel forms of endoscopic procedures are under development: plication of the gastroesophageal junction by endoscopic suturing, thermoablation of the muscle of lower esophageal sphincter and gastric cardia (the Stretta procedure), endoscopic implantation of a biopolymer (Enteryx). These procedures seem effective and rather safe, but they are in the early stages of development and the magnitude of their efficacy is yet undetermined. It is necessary to validate these methods and assess safety by long-term placebo-controlled studies.
Pol Merkur Lekarski 2004
PMID:[Progress in endoscopic antireflux procedures]. 1560 54

Gastroesophageal reflux disease (GERD) is one of the most common publication subjects in gastroenterology field for more than twenty years. The following article is a review of endoscopic methods of treatment of GERD complications. It is interesting that complications of disease are quite common despite the constant development of diagnostics and treatment methods. It is still common to diagnose the disease when the first manifestation is the esophagus constriction. The complication of GERD is the intestinal metaplasia and adenocarcinoma of the distal part of the esophagus. There are effective endoscopic methods of GERD complications treatment. The most effective are esophagus dilations and endoscopic pathological mucosae layer removal like photodynamic therapy, laser ablation, argon coagulation, multipolar coagulation or mucosectomy.
Pol Merkur Lekarski 2004
PMID:[The contemporary endoscopic methods of treatment of gastroesophageal reflux disease complications]. 1560 56

Advances of minimally invasive surgery caused return to operative treatment of gastroesophageal reflux disease (GERD). Authors present advantages and faults of laparoscopic treatment of gastroesophageal reflux disease (in literature and own experience).
Pol Merkur Lekarski 2004
PMID:[Surgical treatment of gastroesophageal reflux disease]. 1560 57

Burning mouth syndrome (BMS) is a predominantly oral condition characterized by the occurrence of a chronic burning that commonly involves the anterior tongue, painful sensation, dryness and taste alterations. The syndrome is reported more often in women, usually without any oral mucosal signs and laboratory abnormalities. Its etiopathogenesis remains poorly understood, and there is no consensus on diagnostic criteria and treatment strategies. Tongue burning is though to be also one of a non-oesophageal symptom of gastro-oesophageal reflux disease. As reported below, although this symptom may well be diagnostically misleading, careful diagnosis based on clinical signs may distinguish patients with BMS from those with reflux disease, and successful management of burning mouth is often enables.
Pol Arch Med Wewn 2004 Nov
PMID:["Burning mouth syndrome"--is not a symptom of gastro-oesophageal reflux disease]. 1577 24

In patients with nasal polyps the colonisation of nasal polyps tissues by Helicobacter pylori was investigated using urease test (GUT plus). In this prospective clinical trials we enrolled 61 subjects who had undergone endoscopic nasal polyps surgery and 30 subjects who had undergone septoplasty (control group) were questioned and biopsy specimens of the removed polyps or the mucosal part of inferior turbinate were tested by the urease test GUT plus. In result Helicobacter pylori was not found in the nasal polyps and mucosal part of inferior turbinate tissue of any of patients including the 43 of 61 patients with nasal polyps and 7 of 30 patients with septum deviation who had symptoms of gastroesophageal reflux. In our study using the urease test GUT plus we were not able to confirm presence of Helicobacter pylori in the nasal polyps tissue. However, further epidemiologic studies using different diagnostic methods would be necessary to confirm presence of Helicobacter pylori as potential underlying pathogenetic mechanism of nasal polyposis.
Pol Merkur Lekarski 2005 Sep
PMID:[Detection of Helicobacter pylori in nasal polyps specimens using urease test GUT plus]. 1635 53

There is the normal coronary artery appearance in 20-30% of coronarographies, made in patients with chest pain and/or positive noninvasive cardiological tests. The simple explanation of this fact is the presence of diseases which may affect coronary perfusion via mechanism independent to the diameter of main coronary arteries. One of them is gastroesophageal reflux disease (GERD). The presence of GERD symptoms in general population concerns about 30-40% of individuals, while non-physiological reflux is stated in 50-65-85% of patients with coronary heart disease (CHD). That means, that GERD is twice more frequent in patients with CHD than in general population. One explanation of the increased frequency of gastroesophageal reflux appearance in patients with CHD is the adverse effect of drugs used in treatment of cardiological diseases. Morover, one of potential mechanisms explaining the influence of esophagal disturbance on the appearance of coronary hipoperfusion may be their common neurological control of the functions. There are three aspects of it: vagal reflexes (esophageal-cardiac reflex), the disturbances of autonomic nervous system balance and changes in visceral pain perception threshold. Visceral reflex can combine GERD and CHD with mechanism of vicious circle: acid gastroesophageal reflux via vagal reflex may cause coronary hipoperfusion, and the products of anaerobic metabolism of cardiomyocytes may cause relaxation of lower esophagus sphincter, facilitating reflux. Additional mechanism connecting GERD and CHD is inflammation caused by Helicobacter pylori infection. The relationship between digestive tract pathology and evolution, as well as progression and complications of atherosclerosis together with similarity of clinical presentation imply the necessity of precise diagnosis of chest pain causes and caution in interpretation of laboratory examination results.
Pol Merkur Lekarski 2006 Jan
PMID:[Gastroesophageal reflux disease and coronary heart disease--coexistence or interrelationship?]. 1661 48

The voice disorders in a case of recurrent laryngeal granuloma with chronic gastroesophageal reflux was described. There was emphasized necessity of complex treatment pharmacological and phoniatric, as well as there were pointed out some indications of microsurgery.
Otolaryngol Pol 2006
PMID:[Voice disorders in recurrent laryngeal granuloma dependend on GERD]. 1682 46

Laryngeal cancer is the most common of head and neck cancers. Neoplasm used to develop basing on DNA mutation which leads to uncontrolled growth and cells' division. It is due to spontaneous mutations or influence of chemical, biological and physical factors. Laryngeal cancer generation is conditioned by many synergic factors. Some of them certainly participate in cancer genesis and this thesis is accepted by medical environment and other of them have been discussed giving different information. Definition of the risk factors role in laryngeal cancer etiology is very difficult especially regarding their contemporary occurrence in one person. Most common risk factors are environmental factors, gastroesophageal reflux, viral infections, diet, radiation, individual predisposition. Some of them, such as cigarette smoking and abuse alcohol are significantly oftener confirmed in patients with neoplasm diagnosis and others' role in developing of illness has been still researched. Thus the purpose of the study was to present so far achievements in laryngeal cancer etiology and to emphasize controversies relating to some factors' role in cancer genesis.
Pol Merkur Lekarski 2006 Jul
PMID:[Laryngeal cancer risk factors]. 1700 3

Excess alcohol consumption has been associated with multiple pathologies of the gastrointestinal tract. The consumption of large amounts of alcohol (hazardous drinking) facilitates acid regurgitation by reducing the pressure of the lower oesophageal sphincter and slowing both oesophageal motility and gastric emptying. Regardless of the type of alcoholic beverage involved lower alcohol doses also have been shown to induce decreased pressure in lower oesophageal, decrease in oesophageal motility and enhanced risk of gastroesophageal reflux disease (GERD). GERD can be important risk factor for oesophageal adenocarcinoma. For identification of hazardous drinking patients we can use AUDIT (Alcohol Use Disorder Identification Test). AUDIT has been created by World Health Organization experts as a simple screening test looking for hazardous drinking people.
Pol Merkur Lekarski 2006 Jul
PMID:[Gastroesophageal reflux disease in hazardous drinkers]. 1700 4


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