Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0017168 (
gastroesophageal reflux disease
)
11,783
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
We summarized proton pump inhibitors(PPI) and histamine H2-receptor antagonist (
H2B
) with reference to acid-related disease. The both drugs act process of gastric acid secretion in parietal cell of stomach. Inhibition of
H2B
is reversible, but that of PPI is irreversible, so period of acting in PPI is longer than that in
H2B
. PPI is more effective than
H2B
in treatment of acid-related disease. Especially PPI is recommended the first choice in
GERD
and NSAID ulcer.
...
PMID:[Effect of H2-receptor antagonist and proton pomp inhibitor on the treatment of acid-related disease]. 2616 73
