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Query: UMLS:C0017168 (gastroesophageal reflux disease)
 11,783 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Using continuous esophageal pH monitoring, we examined 40 asymptomatic babies to evaluate the influence of different positions (prone, supine, right and left side lying position) on gastroesophageal reflux (GER). Several parameters including percent of time with a pH < 4, numbers of reflux episode, numbers of reflux episode lasting more than 5 min, average duration of longest reflux and average pH were studied. All babies were born fullterm and were 1 to 14 days old (average: 4 days). Male to female ratio was 1.7:1. For all parameters, except for average pH, we obtained more favorable results in prone position (p < 0.05). Continuous esophageal pH monitor is a suitable technique to evaluate GER under physiologic circumstances.
Zhonghua Min Guo Xiao Er Ke Yi Xue Hui Za Zhi
PMID:Fifteen-hour continuous esophageal pH monitoring: influence of position on gastroesophageal reflux among asymptomatic babies. 833 82

Esophageal stenosis due to an intrinsic congenital factor is uncommon in infancy. We report a case of a male newborn infant, who was well at birth and presented with foamy sputum from the third day of life and vomiting at 18 days of age. Esophagogram revealed a narrowed segment, about 1 cm in length, at the level of the seventh and eighth cervical vertebral bodies, with proximal dilatation. There was no sign of gastroesophageal reflux. Operative findings: There was no external compression, foreign body or fistula, but a 1 cm length of esophageal stenosis was found. The stenosed segment was hard on palpation. Segmental resection of the stenosed region, with direct anastomosis of the esophagus was performed. Pathological examination of the narrowed segment revealed fibrosis of the submucosa without any tracheobronchial remnent components.
Zhonghua Min Guo Xiao Er Ke Yi Xue Hui Za Zhi
PMID:[Congenital esophageal stenosis with submucosal fibrosis: report of one case]. 833 88

Regurgitation is a common manifestation in infants below the age of one year and a frequent reason of counseling of general practitioners and paediatricians. Current management starts with postural and dietary measures, followed by antacids and prokinetics. Recent issues such as an increased risk of sudden infant death in the prone sleeping position and persistent occult gastro-oesophageal reflux in a subset of infants receiving milk thickeners or thickened "anti-regurgitation formula" challenge the established approach. Therefore, the clinical practices for management of infant regurgitation have been critically evaluated with respect to their efficacy, safety and practical implications. The updated recommendations on the management of infant regurgitation contain 5 phases: (1A) parental reassurance; (1B) milk-thickening agents; (2) prokinetics; (3) positional therapy as an adjuvant therapy; (4A) H2-blockers; (4B) proton pump inhibitors; (5) surgery.
Zhonghua Min Guo Xiao Er Ke Yi Xue Hui Za Zhi
PMID:A critical appraisal of current management practices for infant regurgitation. 923 May 36