Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0017168 (gastroesophageal reflux disease)
 11,783 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Alexithymia and its relation with attachment style were evaluated in a group of 69 patients (men, M age = 46.4 yr., SD = 12.6; women, M age = 44.2 yr., SD = 14.4) affected by Gastroesophageal Reflux Disease. Two self-evaluation questionnaires were used for psychological evaluation, the 20 item Toronto Alexithymia Scale (TAS-20) and the Attachment Style Questionnaire (ASQ). The TAS-20 analysis showed that the clinical sample taken as a whole did not score in the alexithymic range. The inverse correlations between the Confidence ASQ subscale and the Difficulty Communicating Feelings TAS-20 subscale showed that communication of emotions could develop more easily within the framework of a relational context characterized by safety and confidence. In this group of patients this was represented by the referent caregiver.
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PMID:Gastroesophageal reflux disease: alexithymia and attachment style. 1791 82

A total of 167 patients (92 men and 75 women) at the age of 45-65 (mean 47.4 +/- 4.2) years with different digestive system disorders were examined in this study. One group included 48 patients with chronic non-atrophic (largely antral) gastritis associated with helicobacterial infection, the second one comprised 46 patients with intestinal irritation syndrome, the third consisted of 36 patients with gastro-oesophageal reflux disease at the stage of unstable remission in the absence of symptoms of oesophagitis, and the forth group included 38 patients with chronic recurring duodenal ulcer. The Spielberger State-Trait Anxiety Inventory (STAI-i) test and Toronto Alexithymia Scale (TAS) test were used for the assessment. Correlation was estimated using the Spearman coefficient and multiple regression analysis based on the Statistica 6.0 and GraphhPad Prism 4 statistical programs. It was shown that the overall alexithymia rate averaged 66.8%. Taken together with the high occurrence of the reactive anxiety response (74.1%), it suggests a high degree of personality psychosomatization among the examined patients with different digestive system disorders. Patients of groups 1 and 2 are characterized by significant positive correlation between the occurrence of the alexithymic personality type and the reactive anxiety response (r = 0.592, r = 0.593, p > 0.0001). This correlation was weak and insignificant in patients of groups 3 and 4 (r = 0.245, r = 0.190, p > 0.05).
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PMID:[Psychosomatic events in patients with digestive system disorders]. 1881 50

Clinical research showed that asthma control is an achievable target. However, real-life observations suggest that a significant proportion of patients suffer from symptoms and report lifestyle limitations with a considerable burden on patient's quality of life. The achievement of asthma control is the result of the interaction among different variables concerning the disease pattern and patients' and physicians' knowledge and behaviour. The failure in asthma control can be considered as the result of the complex interaction among different variables, such as the role of guidelines diffusion and implementation, some disease-related factors (i.e., the presence of common comorbidities in asthma such as gastroesophageal reflux disease (GERD), sleep disturbances and obstructive sleep apnea (OSA), and rhinitis) or patient-related factors (i.e., adherence to treatment, alexithymia, and coping strategies). Asthma control may be reached through a tailored treatment plan taking into account the complexity of factors that contribute to achieve and maintain this objective.
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PMID:Failure in asthma control: reasons and consequences. 2445 32