Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0017168 (gastroesophageal reflux disease)
11,783 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A 32-year-old patient experienced a postoperative acute myopericarditis following laparoscopic surgery for gastro-oesophageal reflux (Toupet's fundoplication). His medical history was unremarkable, apart from controlled arterial hypertension. Peroperative circulation was stable, except a short hypertensive episode at CO2 insufflation, controlled with nicardipine. A myopericarditis occurred at the fourth postoperative hour, with apical and inferior hypokinesia at ventriculography, ST-segment elevation with unremarkable coronary arteriography. The patient was discharged at day seven, with a NSAIDs treatment. Echocardiography three and nine months later postoperatively, showed an apical akinesia and persistence of the ST-segment modification, without clinical symptoms. Complications of laparoscopic fundoplication is either specific to surgery (gastro-oesophageal injury, diaphragmatic injury, mediastinitis, stenosis) or secondary to pneumoperitoneum (pneumothorax, carbon dioxide embolism). In this case, following an apparently uncomplicated laparoscopy and, except a direct cardiac trauma from a laparoscopic instrument, either coronary artery spasm, or pneumopericardium with CO2, or delayed gas embolism, or preoperative "silent" myopericarditis could be the potential cause of this cardiac complication.
...
PMID:[Acute myopericarditis following laparoscopic treatment of gastroesophageal reflux]. 983 86

We describe a 77-year-old patient with gastropericardial fistula occurring 5 years after laparoscopic surgery for hiatal hernia and gastroesophageal reflux. The patient presented with isolated intermittent substernal pain without fever. Chest radiographs disclosed extensive pneumopericardium and thoracic computed tomography suggested gastropericardial fistula between the pericardium and the surgical wrap, slipped into the thorax. Emergency surgery allowed successful repair through laparotomy via the trans-hiatal approach.
...
PMID:Gastropericardial fistula after failure of laparoscopic hiatal repair. 1120 47

Respiratory complications related to electroconvulsive therapy (ECT) are a rare occurrence. The need for endotracheal intubation during ECT is rarely indicated. We report a case of a 47-year-old woman with severe gastroesophageal reflux disease and depression who was intubated for her first 3 ECT treatments. She developed a small tracheal tear after her third ECT treatment which resulted in subcutaneous emphysema, pneumopericardium, and pneumomediastinum. The tracheal tear resolved spontaneously and ultimately the patient underwent subsequent ECT treatments successfully without intubation. This case is the first reported case of complications related to endotracheal intubation during ECT.
...
PMID:A case of tracheal injury with intubation during electroconvulsive therapy. 1899 34