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Query: UMLS:C0017160 (gastroenteritis)
 11,398 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The efficacy of the Paratect Flex-Bolus for the control of parasitic gastroenteritis in calves was evaluated in a field experiment in the Swiss midland region. The bolus was administered to 9 first year grazing calves at 4 to 5 months of age before turnout on June 26 while 9 calves remained as untreated controls. Both groups were rotated between 8 paddocks that had been pregrazed by older cattle in spring. For a period of 12 weeks the faecal egg output of the treated calves was reduced significantly (p < 0.05) compared to the controls, whereas no significant differences were observed in the mean serum pepsinogen values of both groups. At the end of the experiment (November 14) the bolus-treated calves showed a 4 kg weight gain advantage over the controls which was not significant. The mild infection levels in both groups were probably due to the low pasture contamination with infective larvae throughout the season which most likely resulted from the late turnout of the calves. An outbreak of dictyocaulosis was observed in both groups in October and confirmed that the Paratect Flex-Bolus provides insufficient protection against this infection.
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PMID:[Control of gastrointestinal strongylids in first year calves: use of Paratect Flex bolus at late pasture turnout]. 143 6

An experiment was conducted in calves to investigate the efficacy of a morantel sustained release trilaminate bolus (MSRT) to control gastrointestinal parasitism and to assess the development of immunity during the use of MSRT. Two groups (M and U) of four calves each were infected three times a week with a mixed Ostertagia ostertagi and Cooperia oncophora infection for 12 weeks. Calves of Group M received an MSRT at the start of the experiment. Twenty weeks after the start of the experiment, all animals, including a previously uninfected control group (C), received a challenge with 100,000 Ostertagia and 100,000 Cooperia. After a further 4 weeks all calves were necropsied for worm counts. During the trial calves were weighed and faecal egg counts, larval differentiation and pepsinogen concentrations were determined. The results demonstrated the high level of efficacy of the MSRT in reducing the faecal egg output and preventing parasitic gastroenteritis under conditions of a continuous high rate of infection. Efficacy of treatment was higher for Cooperia than for Ostertagia. Post-mortem worm counts suggested a partially impaired immunity build-up in Group M, at least for Cooperia.
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PMID:Efficacy of the morantel sustained release trilaminate bolus against gastrointestinal nematodes and its influence on immunity in calves. 144 Nov 95

The effect of different larval dose level and dosing regimens on the course of Cooperia oncophora infection in calves was studied. Four groups each of 4 calves were experimentally infected either with 50,000 or 200,000 C. oncophora larvae (L3) given either as single infections or as daily trickle infections. An additional group of calves remained as uninfected controls. The animals were necropsied on week 4 after infection. Mild to moderate clinical signs of parasitic gastroenteritis developed among calves given high doses of larvae, but liveweight gains were not significantly different from those of the uninfected controls. Serum pepsinogen levels of dosed animals were within normal ranges but rose slightly, and on day 14 p.i. they differed significantly from those of the controls. On that occasion, the levels of serum pepsinogen in the trickle infected groups significantly exhibited the levels of the single infected groups. Hypoalbuminaemia was not a feature on any occasion. The various groups did not differ significantly with regard to total worm counts and adult worm counts, but the groups receiving high larval dose harboured significantly more fourth stage larvae than the group receiving low doses of larvae, both in terms of absolute counts and in terms of percentages of total worm burdens. Within the same dose level, there was a tendency of a more even distribution of worms along the small intestine when the infections was given as a single infection compared with a trickle infection. The results indicate that C. oncophora larval dose and dosing regimens may influence the pathogenic effects and to some extent the distribution of the parasite in the small intestine.
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PMID:Experimental infections with Cooperia oncophora in calves. A study with two different larval dose levels and dosing regimens. 144 70

A grazing experiment was performed in the Swiss midland region with 22 first-season calves which were grazed together from May to mid July when they were allocated to two equal groups, one receiving a morantel sustained-release trilaminate bolus (Paratect Flex) bolus, Pfizer, Zurich, Switzerland) and the other one remaining as an untreated control. Each group was moved to a clean pasture on 21 July. The larval contamination on the pasture with the control animals reached 4652 third stage larvae (L3) per kilogram of dry matter (L3 kg-1 DM) after 10 weeks. Parasitic gastroenteritis was observed in two calves of the control group in August, and mean serum pepsinogen levels exceeded 4000 mU tyrosine in this group in September. Eggs from Ostertagia sp. and Cooperia sp. that were excreted by the animals at the beginning of July and the end of August showed similar hatching rates of 94% and 99%, respectively. In the calves of the bolus group the egg output was reduced by 95% within 14 days of administration of the bolus. Larval contamination on the pasture of the bolus group was zero until the beginning of September when a slight increase occurred, reaching 793 L3 kg-1 DM in October. At the end of the trial the bolus-treated calves had a mean weight gain advantage of 18 kg (P < 0.05) compared with the controls. The results confirm that a second generation of larvae developed on pasture in August and September and caused parasitic gastroenteritis in first-year grazing calves in late summer. The relevance of the results for the prophylaxis of parasitic gastroenteritis in calves in mixed grazing systems with calves and older cattle is discussed.
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PMID:Epidemiology of trichostrongylidosis in cattle: development of infective larvae in the second part of the grazing period and their contribution to infections in the same year. 148 12

The effectiveness of albendazole in a controlled-release bolus in controlling gastrointestinal nematodes in lambs was assessed during the summer of 1986. Faecal egg counts were almost entirely negative throughout in the treated group and larval challenge remained low at below 2000 larvae kg-1. Untreated control lambs showed a characteristic pattern of auto-infection, culminating in a peak pasture larval count of over 70,000 larvae kg-1 and an outbreak of parasitic gastroenteritis in September associated with a serum pepsinogen concentration of 1.183 IU tyrosine and a mean worm burden of 91,165 nematodes at necropsy, including Ostertagia, Trichostrongylus and Nematodirus species. Subject to the restrictions imposed by the size of the bolus, this was considered to be a highly effective method of seasonal parasite control.
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PMID:The efficacy of an albendazole intraruminal controlled-release device against gastrointestinal parasitism in lambs. 150 86

Two outbreaks of parasitic gastroenteritis were observed in a group of 10 first-season grazing calves, one in mid-July and one in mid-September. In both cases emergency anthelmintic treatment was needed to prevent further damage. Severe clinical signs were observed together with high faecal egg counts and high serum pepsinogen and gastrin concentrations. Low total protein and albumin concentrations were also observed, especially during the second outbreak. The ostertagia antibody levels followed a similar pattern to the serum pepsinogen and gastrin concentrations. At the end of the housing period a mild type II ostertagiasis was observed. In the second grazing season the heifers did not show any signs of parasitic gastroenteritis, but there was a serious outbreak of husk which required treatment.
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PMID:Observations on parasitic gastroenteritis and parasitic bronchitis in calves over two grazing seasons. 226 45

When they were turned out to grass in May 1987 for their first season, 10 calves were dosed with a 5 x 750 mg oxfendazole pulse release bolus (OPRB) and a monensin sodium rumen delivery device (RDD); eight calves received one OPRB; 10 calves received one RDD and eight calves received neither bolus. Each group was set-stocked on individual paddocks which had been grazed during the previous season by cattle which developed clinical parasitic gastroenteritis and bronchitis (husk). In July, before they were due to be moved to new pastures in mid-summer, and before they were dosed strategically with levamisole HCl, some of the calves not dosed with an OPRB succumbed to clinical parasitic gastroenteritis and husk and received emergency anthelmintic treatment, after which no further clinical episodes occurred. The 'dose and move' strategy was implemented in early August after which both groups not dosed with an OPRB were set-stocked together until the trial ended on October 14, 147 days after turn out. The two groups of calves which had received the OPRB were also moved to new pasture and set-stocked together until the end of the trial. No evidence of clinical helminthiases developed in either of the two groups of calves dosed with OPRBs and their faecal worm egg and larval counts, and plasma pepsinogen activities remained low. They gained significantly more weight than the two groups of calves not dosed with OPRBs (P less than 0.001). The bolus types were compatible and induced no untoward side-effects when used together.
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PMID:Concurrent use of the oxfendazole pulse release bolus and the monensin rumen delivery device in young grazing cattle. 277 30

The efficacy of the oxfendazole pulse release bolus system for the control of parasitic gastroenteritis and parasitic bronchitis in first-season grazing calves was evaluated in Belgium. Twenty-two calves were allocated to two groups. The calves in one group received a bolus at the time of turn out, while the other group remained untreated. The efficacy of the bolus was assessed by comparison of faecal worm egg counts, plasma pepsinogen concentrations, the antibody response to Ostertagia, Cooperia and Dictyocaulus species total plasma protein and albumin concentrations, and weight gains throughout the grazing season and the housing period. The oxfendazole pulse release bolus provided good control of parasitic gastroenteritis dominated by ostertagia. The effects of parasitic gastritis were greatly reduced as shown by the significantly lower values of serum pepsinogen and ostertagia antibody titres. The use of the bolus further reduced the adverse effects of parasitism as indicated by better liveweight gains and normal total plasma protein and albumin concentrations whereas in the untreated control group hypoproteinaemia and hypoalbuminaemia were observed. Most animals exhibited clinical signs of parasitic bronchitis at the end of the grazing season, and the bolus may not adequately control parasitic bronchitis in all cases at all times.
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PMID:Use of an oxfendazole pulse release bolus in the control of parasitic gastroenteritis and parasitic bronchitis in first-season grazing calves. 296 61

Four groups, each of six male Friesian calves, were set-stocked on separate 0.66 ha paddocks from May 7 until October 23 1986. Each of the animals in groups 1 and 4 was dosed with an oxfendazole pulse release bolus at turn out whereas the animals in groups 2 and 3 were left untreated. Parasite-free naive tracer calves were introduced into each paddock for a limited period 12 days after turn out and again at the end of the trial. No adverse reactions or clinical signs were observed in either of the groups of calves which received boluses. The development of clinical parasitic gastroenteritis in both the untreated groups necessitated the humane slaughter of two animals and emergency anthelmintic treatment of the remainder. The lower plasma pepsinogen concentrations, and lower faecal egg and larval counts and worm burdens post mortem, together with the absence of clinical signs of parasitic gastroenteritis and bronchitis in the treated calves, confirmed the high efficacy of the bolus treatment.
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PMID:Control of naturally acquired bovine parasitic bronchitis and gastroenteritis with an oxfendazole pulse release device. 297 64

A field experiment is described which evaluates the use of an experimental albendazole pulse release bolus (E-bolus) on gastrointestinal parasitism. The bolus was administered at turnout to 9 first-season grazing calves and 9 animals were kept as controls on separate pasture. Dry summer months accounted for low infection levels in the calves; no cases of parasitic gastroenteritis were observed. The E-bolus introduced at the start of the grazing season provided moderate control of gastrointestinal parasitism. The beneficial effect of the treatment was demonstrated by lower strongyle egg counts and significant differences in ELISA extinctions for Ostertagia, Cooperia and Dictyocaulus. However pepsinogen values were elevated in the bolus-treated group, probably because of the long interval (31 days) between the pulsed treatments. Although not significant there was a trend for the bolus-treated group to gain more weight than the controls.
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PMID:Field evaluation of an experimental albendazole pulse release bolus in the control of parasitic gastroenteritis in first-season grazing calves. 319 48


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