Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0017160 (
gastroenteritis
)
11,398
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Serum samples from wild Hanuman langurs (Presbytis entellus) from Mysore State, India, were compared to samples from a laboratory colony from Davis, Calif., for antibodies to rotavirus, which is an important cause of
gastroenteritis
in mammals. Animals from the laboratory colony had a higher frequency and higher levels of antibody than wild animals. It is likely that wild populations of langurs have a much lower incidence of rotaviral infection than laboratory populations, which are exposed to both crowded conditions and rotaviruses from other species.
J Med
Primatol
1982
PMID:Rotavirus antibodies in hanuman langurs (Presbytis entellus). 628 54
Rotavirus and norovirus are associated with a substantial burden of diarrheal disease in humans and some animals, but their role in acute viral gastroenteritis in non-human primates has not been established. We examined sera from five species of Old and New World monkeys and chimpanzees for antibodies to rotavirus and norovirus by enzyme immunoassays using RRV and three recombinant human norovirus capsid proteins, respectively. Most (88%) of the 3 Old World monkey species (mangabey, pigtail, and rhesus) and apes were seropositive for rotavirus. Norovirus antibody was prevalent in the three monkey species, with 53% (44/83) and 58% (48/83) seropositive for GI and GII strains, respectively. Eleven (92%) of the 12 chimpanzees tested were seropositive for GI norovirus. Given the high rate of infection with both viruses, the role of these agents in causing acute
gastroenteritis
in non-human primates and the value of these animals as models of infection and disease need to be assessed.
J Med
Primatol
2004 Feb
PMID:Prevalence of rotavirus and norovirus antibodies in non-human primates. 1506 30