Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0017160 (gastroenteritis)
 11,398 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Hospitalized infants suffering from acute diarrhea were used to test simple bedside methods of determining reducing substances and pH in multiple fresh stool specimens. 332 infants were tested, and thetests were useful in detecting a reduced capacity to tolerate lactose in 77% of these patients. Lactose intolerance was considered to be present when the stools had a carbohydrate content greater than .25% and/or a pH of less than 6. 75 of 77 lactose-tolerant patients recovered within 3 weeks of administration of a milk formula, whereas 111 of 195 with mild intolerance and 13 of 60 with severe lactose intolerance recovered while receiving the milk formula. Diarrhea of greater than 3 weeks duration occurred in 27% of those cases with mild and in with untreated severe intolerance; however, with prompt dietary treatment, a 62% of those cases favorable response always occurred. Lactose intolerance was positively correlated with increased severity of malnutrition; there were no correlations with previous episodes of gastroenteritis, with presence of enteropathogens or with associated infections. When antibiotic therapy was instituted, the stool pH increased toward alkaline, but the excretion of carbohydrates was not modified.
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PMID:Carbohydrate intolerance in infants with diarrhea. 517 Nov 4