Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0017160 (gastroenteritis)
 11,398 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

It is not known whether the presence of Herpes simplex virus in the throat of elderly patients with severe gastroenteritis and pulmonary implications is of clinical relevance. We cultured throat swabs and faeces of elderly patients with (n = 11) and without (n = 12) severe Salmonella gastroenteritis for viruses and bacteria to study the aetiology of respiratory complications. Complement fixation titers for anti-Herpes simplex antibodies in paired sera were also ascertained. Throat swabs of 6 out of 11 elderly patients with severe Salmonella enteritidis gastroenteritis were positive for Herpes simplex virus type 1. However, a four-fold increase of anti-Herpes simplex antibody titers in paired sera could not be demonstrated. None of the 12 throat swabs of elderly patients without gastro enteritis grew Herpes simplex virus. No other pathogens causing pulmonary complications could be demonstrated in throat swabs of the elderly patients. Herpes simplex virus present in the throat of the elderly patients was very probably not the agent responsible for the pulmonary complications and consequently treatment with acyclovir was not indicated. Weakness caused by severe gastroenteritis and the relative T-lymphocyte immunodeficiency state in the elderly probably enhanced the shedding of Herpes simplex virus in the throat of the elderly patients, without clinical relevance.
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PMID:Clinical relevance of herpes simplex virus in the throat of elderly with Salmonella enteritidis gastroenteritis. 134 52

One hundred forty-two cases of salmonella infection seen in Asir region, Southern Saudi Arabia, during the period of 1989-1991 inclusive, were analyzed. Ninety-four cases were found to have enteric fever and 48 cases were found to have, Salmonella enteritidis gastroenteritis. Enteric fever is more common in non-Saudis (64%) than in the indigenous Saudi population (34%). Salmonella enteriditis gastroenteritis is more common among the Saudi population (75%) than non-Saudis (25%). The clinical presentation of both types of salmonella infection is outlined. Enteric fever is more common among expatriates who recently came from India (40.5%), Egypt (10.6%), Pakistan (6.4%), and Syria (4.3%). Salmonella typhi resistant to tetracycline, ampicillin, and chloramphenicol are more common among Indian patients (75% of resistant cases) and Syrian patients (12.5-28% of resistant cases). Resistance to cotrimoxazole is commonly encountered in Indians (50% of resistant cases) and Egyptians (33.3%). Salmonella enteriditis resistant to tetracycline, ampicillin, and chloramphenicol is more common among Saudis (66.7% of resistant cases) and Filipinos (16.7-33.3% of resistant cases). Recommendations regarding screening of expatriates for enteric fever and proper drug therapy of possible resistant cases are outlined.
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PMID:Salmonella infections in Asir region, southern Saudi Arabia: Expatriated implications. 1759 Jun 69