Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0017160 (gastroenteritis)
 11,398 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

During a 5-month period, 513 stool samples submitted to the enteric laboratory at the University Hospital of the West Indies were examined for Cryptosporidium. Oocysts were detected in 4.9% of all stools, 7.3% of diarrhoeal stools, 19.5% of stools from malnourished children and 23.7% of stools from malnourished children with diarrhoea. Cryptosporidium was the sole pathogen detected in all 25 positive stools, and was the second most frequent enteric isolate. All cases of cryptosporidiosis occurred in children less than 2.5 years of age. All 15 malnourished children were admitted to hospital where they presented with dehydration (87%), vomiting (93%), fever (100%) and diarrhoea which lasted an average of 15.3 days. Two of these children died. In contrast, dehydration (20%), vomiting (40%) and fever (50%) were less common and diarrhoea less protracted in well-nourished children, four of whom were admitted to hospital. This preliminary report suggests that cryptosporidial gastroenteritis presents with increased frequency and severity in malnourished compared with well-nourished Jamaican children.
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PMID:Cryptosporidiosis in well-nourished and malnourished children. 360 64

Two different groups of patients with diarrhoea, altogether 1,478 individuals, were examined for cryptosporidium oocysts. The technique used was feces concentration and staining according to a modified Ziehl-Neelsen method. 20 cases of cryptosporidiosis (3%) were found among 698 consecutive patients with acute gastroenteritis. In feces samples sent for parasitological examination from 780 patients, cryptosporidia were found on 9 occasions (1%). None of 519 healthy persons excreted cryptosporidia. 19/29 patients with cryptosporidiosis had recently been abroad and in 8 of these additional enteric pathogens were found. The median duration of diarrhoea was 14 days. All patients except 1 were cryptosporidia-negative in faeces within 2 months. An immunosuppressed patient excreted cryptosporidia for 14 months.
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PMID:Cryptosporidiosis in southern Sweden. 361 90

During a two year period 48 children admitted to hospitals in the Blackburn district were found to have cryptosporidium in stool samples. Cryptosporidium accounted for 6% of the 742 cases of childhood gastroenteritis, being as common as campylobacter. Altogether, 89% of children with cryptosporidiosis had diarrhoea, which was usually offensive and watery, and 80% vomited, the mean duration of both symptoms being six days. A substantial proportion were moderately ill with dehydration and persistent vomiting. Over half of all cases were aged 2 years or more and 37% were over 5 years. Most of the ill children were over 2 years, in contrast with other cases of gastroenteritis. Eight children were less than the 3rd centile for weight and three of these were investigated for failure to thrive. Only 6% of cases occurred in Asian children, but Asians accounted for 32% of all admissions with gastroenteritis and 59% of admissions with shigella. This unexpected ethnic difference may be due to limited contact with animals among Asians or to differences in diet.
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PMID:Two year study of cryptosporidium infection. 361 72

Clinicians have only recently become aware that Cryptosporidium is a major human pathogen, causing a self-limited gastroenteritis in immunocompetent individuals and profound enteropathy in the immunocompromised. Among the immunologically intact, children appear more prone to clinically significant cryptosporidiosis than do adults. Diagnosis is most easily made by a specialized three-step stool examination, but mucosal biopsy may also be necessary to establish the diagnosis. Although no satisfactory antibiotic therapy exists today, cases of cryptosporidiosis in the community and hospital should be identified in order to contain human transmission. Only then can spread from immunocompetent individuals to immunodeficient individuals be avoided.
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PMID:Diagnosis and treatment of cryptosporidiosis in children. 369 59

We describe an outbreak of human cryptosporidiosis in 5 veterinary students in contact with experimentally infected calves. All persons experienced symptoms of gastroenteritis, with the main complaint of diarrhoea lasting for 1-13 days. The persons recovered spontaneously; one was hospitalized for 10 days. The diagnosis was based on the demonstration of Cryptosporidium oocysts from stools by the smear method and the formalin-ether concentration method, both combined with the acid-fast staining technique. Both methods gave almost equal results. The role of Cryptosporidium as an occupational risk is discussed.
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PMID:Outbreak of cryptosporidiosis among veterinary students. 370 65

Cryptosporidiosis in Children. During an 11-month survey, Cryptosporidium oocysts were found in the stools of 20 of 142 children admitted with gastroenteritis. Five of these 20 patients also excreted other enteropathogens. The clinical findings in 18 children infected with cryptosporidia could be analyzed. All patients were immunocompetent. Watery diarrhea, vomiting and anorexia were the most frequent symptoms. Differences in the clinical findings were observed between children aged one to two years and older children. The older children remained ill for 4.1 days compared to 19.9 days in the younger children. The younger children also presented a history of recurrent diarrhea. Problems of etiology and therapy are discussed. Cryptosporidia should be considered as a cause of diarrhea in children.
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PMID:[Cryptosporidiosis in children]. 375 46

A two-year prospective survey of patients with diarrhoea at a children's hospital detected 65 cases of cryptosporidiosis; 56 were index cases representing 1.4% of patients examined. There was a marked seasonal variation with fewer index cases in July-September (0.4-0.6%) than February-April (3-5%). All four adult cases were contacts of infected children and 21 (32%) of the patients were 12 months old or younger. Cryptosporidium was the fourth commonest diagnosed cause of gastroenteritis, the second most common non-viral cause, was responsible for 7.2% of all cases, and 14.7% of non-viral cases where a cause was identified. As such it should be sought routinely in cases of gastroenteritis in children.
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PMID:The incidence of cryptosporidiosis: a two-year prospective survey in a children's hospital. 395 Mar 90

During a 7-month period, 2,252 fecal samples submitted for routine microbiological examination from 1,621 patients were screened for Cryptosporidium oocysts by the auramine staining method with Kinyoun acid-fast stain as the confirmatory stain. Cryptosporidium oocysts were detected in fecal samples from 19 (1.2%) patients, 18 of whom had gastroenteritis. Diarrheic stools from 14 of these 18 patients were negative for the usual enteropathogens but contained the oocysts in moderate to large numbers. Although Cryptosporidium oocysts were found in patients of all ages, they occurred slightly more frequently in infants and children than in the rest. Cryptosporidium species was one of the common enteropathogens identified in fecal samples submitted for routine parasitological examination during the period of the survey and was second only to Giardia species in terms of frequency. Considering cryptosporidiosis in the differential diagnosis of gastroenteritis in immunocompetent persons and including a search for Cryptosporidium oocysts in routine parasitological examinations of fecal samples appear warranted.
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PMID:Occurrence of Cryptosporidium oocysts in fecal samples submitted for routine microbiological examination. 404 98

Cryptosporidiosis, a newly recognized parasitosis of humans is being identified with increased frequency in immunocompromised and more recently in immunocompetent persons with gastroenteritis and or diarrhea. It has been found in the Philippines for the first time in children seen at the San Lazaro Hospital in Manila. A total of 735 stool specimens from adults and children with diarrhea were examined by the Ziehl-Neelson and Kinyoun acid-fast methods and 2.9% of the children 6 to 20 months of age were found passing Cryptosporidium oocysts. This parasitic infection should be considered in the differential diagnosis of cases of diarrhea in both immunodeficient and immunocompetent persons.
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PMID:Cryptosporidiosis in Philippine children. 407 Nov 97

Stool samples from 692 children hospitalized with symptoms of gastroenteritis, were examined for Cryptosporidium parvum. The oocysts were found in 17 (2.4%) children. There was no association with age, sex or location of household. However, relatively higher rate of oocyst exclusion was found among 2-month- to 3-year-old groups (50%) and among children from villages (43%). Six children from the group of infected were additionally screened for general immunocompetence. Four of these exhibited signs of immunodepletion of IgA isotype in serum. This study has established that cryptosporidiosis occurred rather sporadically among children in the examined groups. Further study was undertaken to provide relevant information whether wild small mammals are a zoonotic reservoir of Cryptosporidium sp. Samples were collected from autumn 1989 until spring 1991 in northern Poland, District Mazury Lake. Twenty percent (66 of 330) of the examined mammals were naturally infected with Cryptosporidium sp.: 55 of 275 Clethrionomys glareolus, 6 of 39 Apodemus flavicollis, and 5 of 16 Sorex araneus were positive. The histological study clearly indicates that the population of C. glareolus was infected with C. parvum. Endogenous stages were found in duodenum near the pylorus. The intensity of infection in those animals was generally low, and relatively small numbers of trophozoites and oocysts were found. This report indicates that C. glareolus and possibly other rodents have the potential to act as reservoirs for C. parvum.
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PMID:Cryptosporidiosis in Poland: clinical, epidemiologic and parasitologic aspects. 801 31


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