Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0017160 (gastroenteritis)
 11,398 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

One hundred fifty-two strains of Clostridium were isolated from 144 patients over a 14-month-peroid. These included 23 recognized species and 23 strains that were unclassified. Soft tissues or abscesses yielded 84 strains of Clostridium. Intraabdominal sites predominated, but clostridia were recovered from empyema, carcinoma, frostbite with gas gangrene, muscle abscess, aortic graft, and brain abscess. Blood cultures yielded 65 strains of Clostridium from 49 patients, representing 0.3% of 16,314 blood cultures (or 2.6% of 2,168 positive cultures). Clostridium perfringens was most common in blood, accounting for 37 isolates (57%). Clostridial bacteremia was often unrelated to the clinical setting and was found in alcoholics with aspiration or Streptococcus pneumoniae pneumonia, pulmonary tuberculosis, empyema, meningococcemia, and infantile gastroenteritis. In 20 of the 49 patients (41%), aerobic or other anaerobic bacteria were cultured concurrently from the blood. Thus, clostridial bacteremia should be interpreted with caution since there may be little correlation with the patient's clinical condition.
 ...
PMID:Isolation of Clostridium in human infections: evaluation of 114 cases. 80 93

Three full-term neonates contracted a hospital infection with Salmonella panama derived from the mother of one. Two had bacteraemia and meningitis; one developed a brain abscess and the other recurrent meningitis at two months. The third neonate had gastroenteritis only. Six months later they had developed normally and two were still excreting salmonellae in the stools.
 ...
PMID:Neonatal Salmonella panama infection with meningitis. 142

The effect of consanguinity on fertility, reproductive loss, and development disorders were studied in South India. The population investigated included 377 unselected mothers who, along with their children, were followed up longitudinally. Each mother was interviewed regarding consanguinity, details of reproductive performance, and death of any offspring. Marriages were classified as unrelated or between uncle and niece, between first cousins, between first cousins once removed, between second cousins, between second cousins once removed, and between third cousins. Among the 377 marriages, 156 (41.4%) were consanguineous and 221 (58.6%) were nonconsanguineous. Consanguinity was more prevalent among Hindus than among Muslims or Christians. The mean and standard deviation in the age of women were similar in all age categories at the time of the study, but the numbers of pregnancies and live births were higher in consanguineous than in nonconsanguineous unions. The mean number of living children were not significantly different in the 2 groups. Although the intrauterine wastage showed no significant difference between the 2 groups, extrauterine loss of life, especially the death rate of children, was higher in the consanguineous marriages. The causes of death in the nonconsanguineous group were diptheria, tuberculosis meningitis, acute nephritis, convulsive disorder, and brain abscess. The causes of death in the consanguineous group were measles with complications, gastroenteritis, pyogenic meningitis, whooping cough, convulsive disorder, undiagnosed fever, burns, and undiagnosed illness with persistent vomiting. In regard to developmental anomalies, in only 1 instance was the condition unequivocally due to autosomal recessive inheritance. In the majority of the remaining cases the disorders were polygenic or multifactorial in origin. The frequency of developmental anomalies was significantly more frequent among the children of consanguineous parents.
 ...
PMID:Reproductive wastage and developmental disorders in relation to consanguinity in south India. 731 41

Focal intracranial infections caused by Salmonella are rare, especially those produced by S. enteritidis. We describe the case of a 26-month-old girl who underwent surgery for a frontoparietal ependymoma and presented with epidural empyema and a brain abscess due to S. enteritidis following an episode of gastroenteritis. The child was successfully treated by surgical drainage along with 9 weeks of antibiotic therapy including ciprofloxacin.
 ...
PMID:Brain abscess and epidural empyema caused by Salmonella enteritidis in a child: successful treatment with ciprofloxacin: a case report. 1982 16

Listeria monocytogenes is a ubiquitous organism that can potentially cause gastroenteritis and, less commonly, central nervous system infections. Brain abscess is rare and often associated with immunocompromised status. We report a case of multiple abscesses caused by Listeria in a previously immunocompetent elderly patient who developed a headache and left-sided hemiparesis over the course of days. Neuroimaging studies revealed multiple ring-enhancing lesions in the brain and midbrain territories. Blood culture, brain tissue aspirate, and cerebrospinal fluid nucleic acid amplification test were positive for Listeria. Extensive immunologic workup revealed no primary or secondary immunodeficiency disorders. After the initiation of antibiotics, the patient showed gradual clinical improvement and went to a skilled nursing facility after two weeks.
 ...
PMID:Multiple Listeria Abscesses in an Immunocompetent Patient. 3206 14

Salmonella infection is an international public health concern. Salmonella organisms are Gram-negative bacilli that belong to the family Enterobacteriaceae, and more than 2500 Salmonella serovars have been described. The most common clinical presentations of Salmonella infection are gastroenteritis, bacteremia, enteric fever, and chronic carrier state. Other rare extraintestinal infections include cellulitis, urinary tract infection, pneumonia, endocarditis, meningitis, brain abscess, and osteomyelitis. Salmonella species resistant to first-line treatment such as ampicillin, chloramphenicol, and trimethoprim-sulfamethoxazole are referred to as multi-drug resistant. In recent years, extensively drug-resistant (XDR) Salmonella have appeared in Pakistan; XDR strains are resistant to multiple antibiotics, including first-line antibiotics, fluoroquinolones, and third-generation cephalosporins. We report two interesting pediatric cases who presented with uncommon Salmonella infection. The first case is a child diagnosed with XDR typhoid fever in a country where the strain is not endemic. The second case is a child who presented with a Salmonella urinary tract infection who is otherwise immunocompetent and has no apparent underlying structural abnormalities of the urinary tract.
 ...
PMID:What is Behind Salmonella? Unusual Presentation in Two Pediatric Cases. 3271 6