Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0017160 (gastroenteritis)
11,398 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Attempts to control a summer diarrhoea in grazing Finnish landrace lambs which had been unresponsive to anthelmintics and coccidiostats were made by supplementing them with cupric oxide particles and withdrawing a magnesium-rich mineral, while maintaining parasite control measures. The diarrhoea persisted from July to September and plasma pepsinogen activities were raised, suggesting that the anthelmintic did not prevent abomasal damage; the jejunum of an affected lamb showed lesions of parasitic gastroenteritis. Small responses to cupric oxide particles and larger responses to the withdrawal of magnesium were deceptive, possibly being confounded by differences in parasite challenge. In another experiment Finnish landrace lambs were more susceptible to diarrhoea than Suffolk cross lambs in autumn. The susceptibility was then linked to a strong inhibition of worm egg output and may have been caused by a hypersensitive mucosal response to the larval challenge. Plasma pepsinogen concentrations were again raised in the Finnish landrace lambs and did not decline after treatment with anthelmintic, whereas the concentrations increased later in the Suffolk cross lambs, and were apparently responsive to anthelmintic. The cases of diarrhoea were similar to 'July disease' and may have been caused by continuous nematode infections which were only briefly controlled by drenches. Anthelmintic-unresponsive diarrhoea is the term proposed for the disorder, which may be controllable by devices releasing anthelmintic continuously or by a move to less infected pasture. Faecal egg counts remained low in the condition and were diagnostically misleading.
Vet Rec 1995 Sep 23
PMID:A putative role for larval nematode infection in diarrhoeas of lambs which did not respond to anthelmintic drenches. 864 44

The first and only outbreak of transmissible gastroenteritis in pigs in Ireland occurred in 1984 in a 650-sow unit which was one of three such units owned by one enterprise which supplied pigs to a 12,000 head fattening unit in the same ownership. The depopulation of the clinically infected unit and extensive serological monitoring of pigs in the other units and in pig farms throughout the country has proved successful in the elimination of transmissible gastroenteritis infections from pigs in Ireland.
Vet Rec 1996 Mar 02
PMID:Elimination of transmissible gastroenteritis virus from a pig farm by culling and serological surveillance. 868 50

The efficacy of a fenbendazole slow release bolus in controlling nematode infections of first-season cattle was evaluated in a field study in northern Germany. Two groups, each of 11 male calves, were set-stocked on separate pastures from May until October 1989 (157 days). The animals of one group were given the bolus at turnout and the animals of the control group were treated with fenbendazole (7.5 mg/kg bodyweight) eight weeks after turnout. Clinical inspections and measurements of faecal egg and larval counts, herbage trichostrongyle larval counts, plasma pepsinogen concentrations and bodyweight were made throughout the study. All the animals were slaughtered for worm counts and the evaluation of carcase quality two weeks after housing. The pasture grazed by the control group showed a marked increase in trichostrongyle larvae from late August onwards and, as a result, the control calves had increasing faecal egg counts and increased plasma pepsinogen concentrations in the latter part of the grazing season, although no clinical signs of parasitic gastroenteritis were apparent. The fenbendazole slow release bolus suppressed the trichostrongyle infections during the grazing season, and larval counts on the pasture grazed by the bolus-treated group remained low throughout the study. Postmortem examination showed that the bolus-treated calves harboured significantly (P < 0.01) fewer trichostrongyle worms, including inhibited stages, than the controls. Because of an inadequate lungworm challenge during the grazing season it was not possible to evaluate the efficacy of the fenbendazole slow release bolus in preventing parasitic bronchitis. At slaughter, the bolus-treated animals weighed more than the controls and tended to have a better carcase quality.
Vet Rec 1997 Apr 12
PMID:Field evaluation of a fenbendazole slow release bolus in the control of nematode infections in first-season cattle. 914 Dec 22

A retrospective study was made of natural infections with Isospora suis in nursing piglets, recorded from April 1994 to May 1997, to determine the prevalence, microscopical lesions and other microorganisms associated with coccidiosis. One hundred and five (17.3 per cent) of the 605 nursing piglets submitted from 304 pig farms were diagnosed positive for coccidiosis. The affected piglets were from seven to 20 days old, with a mean age of 11.1 days. Coccidiosis occurred in each year but the incidence peaked in July (15 cases, 14.3 per cent), September (15 cases, 14.3 per cent), October (16 cases, 15.2 per cent) and November (18 cases, 17.1 per cent) and was lowest in May (no cases), August (two cases, 1.9 per cent) and June (four cases, 3.8 per cent). Histopathologically, villous atrophy resulting from the necrosis and sloughing of epithelial cells was a prominent feature of infection with I suis. In 49.5 per cent of the nursing piglets, other enteropathogens were identified, Escherichia coli (47.6 per cent) and transmissible gastroenteritis virus (3.8 per cent) being the most commonly diagnosed. Forty-five of 50 E coli isolates associated with coccidiosis tested negative by polymerase chain reaction for enterotoxigenic virulence factors, such as fimbriae and enterotoxins.
Vet Rec 1998 Oct 10
PMID:Diarrhoea in nursing piglets associated with coccidiosis: prevalence, microscopic lesions and coexisting microorganisms. 980 91

Forty-seven common dolphins (Delphinus delphis ponticus) were stranded on the northern shores of the Black Sea between mid-July and early September 1994, more than in previous or subsequent years. Two of the 47 dolphins were examined in detail to try to determine the cause of the increased stranding rate. Their lesions included broncho-interstitial pneumonia with type II epithelial cell hyperplasia and multinucleate syncytial cells, neuronal necrosis, gliosis, and non-suppurative meningitis of the brain, necrotic stomatitis, gastroenteritis and cholangitis, and lymphoid depletion of the spleen and lymph nodes. The diseased tissues stained positive in an immunoperoxidase test, using a polyclonal antiserum to measles virus as the primary antibody, and electron microscopy showed that they contained regularly-shaped intranuclear particles about 22 nm in diameter. They were positive by the polymerase chain reaction (PCR) for the nucleoprotein gene of morbillivirus. However, there was no evidence of morbillivirus in frozen tissues either by virus isolation or by antigen capture ELISA. The concentration of sigma DDTS in the blubber of both dolphins was about 50 to 100 times higher than the levels in toothed cetaceans from the North Sea, North Atlantic Ocean, and Baltic Sea. The lesions were consistent with those found in other species with morbilliviral disease, and the positive immunoperoxidase test, PCR and electron microscopical examination confirmed a morbillivirus as the primary cause of these lesions.
Vet Rec 1999 Jan 23
PMID:Epizootic of morbilliviral disease in common dolphins (Delphinus delphis ponticus) from the Black sea. 1009 12

A multiplex reverse-transcriptase-PCR (RT-PCR) procedure was developed for the simultaneous detection of porcine epidemic diarrhoea virus (PEDV) and transmissible gastroenteritis virus (TGEV) in preweaning pigs with diarrhoea. The membrane gene of PEDV and the nucleocapsid gene of TGEV were chosen as targets. The PCR products of PEDV and TGEV had molecular sizes of 412 and 612 base pairs, respectively. Primers from PEDV did not react with any TGEV tested and vice versa. In addition, the primers did not react with other pig viruses. The multiplex RT-PCR was able to detect 10 tissue culture-infective doses 50 per cent (TCID50)/ml of PEDV or TGEV with each of the primer sets for PEDV and TGEV, respectively. The RNAS of PEDV and TGEV were detected directly in intestinal and faecal samples from pigs infected experimentally with either virus. The results of the assay correlated well with the results of virus isolation. None of the five control specimens was positive. PEDV was detected in 10 intestinal and nine faecal samples, and among the nine positive faecal samples two were culture-negative. TGEV was also detected in 10 intestinal and nine faecal samples, and among the nine positive faecal samples, three were culture-negative.
Vet Rec 2000 May 27
PMID:Detection and differentiation of porcine epidemic diarrhoea virus and transmissible gastroenteritis virus in clinical samples by multiplex RT-PCR. 1087 84

Salmonellosis in cattle due to S Dublin and S Typhimurium, and in pigs due to S Typhimurium. Blue-green algae (cyanobacterium) toxicity suspected on a dairy farm. Outbreaks of parasitic pneumonia diagnosed in grazing cattle across Scotland. Parasitic gastroenteritis in lambs seen in association with deficiencies of trace elements. Viral insult suspected in outdoor sows affected by hindlimb paresis and paralysis. These are among matters discussed in the disease surveillance report for August from SAC Consulting: Veterinary Services (SAC C VS).
Vet Rec 2010 Nov 06
PMID:Disease due to Salmonella diagnosed in cattle and pigs in Scotland. 2125 6

Increased prevalence of Johne's disease in sheep; abomasal damage in young cattle due to ostertagiosis; parasitic gastroenteritis in young sheep due to Nematodirus, Teladorsagia and Chabertia species; Streptococcus suis serotype 2 associated with a range of clinical signs in pigs; respiratory cryptosporidiosis confirmed in wild red grouse. These are among matters discussed in the disease surveillance report for October 2010 from SAC Consulting: Veterinary Services (SAC C VS).
Vet Rec 2011 Jan 08
PMID:Increase in the prevalence of Johne's disease in sheep in Scotland. 2125 30

Parasitic gastroenteritis diagnosed in lambs by all veterinary investigation centres, Clostridium perfringens epsilon enterotoxaemia suspected in two cows, Comparative quarterly porcine reproductive and respiratory syndrome diagnoses reach a 10-year peak, Failure of an entire colony of gulls in Cumbria, Endoparasitism the predominant feature in exotic farmed animals, These are among matters discussed in the Animal and Plant Health Agency's (APHA's) disease surveillance report for September 2014.
Vet Rec 2015 Jan 24
PMID:Parasitic gastroenteritis in lambs widespread. 2561 48

Erysipelas diagnosed in turkeys, sheep and pigs. Parasitic gastroenteritis reported in cattle on several farms. Unusual presentation of Actinobacillus suis causing spinal abscesses in pigs on a breeder-finisher unit. First APHA diagnosis of oedema disease in pigs in East Anglia for many years. Infectious coryza confirmed in a hobby breeding flock. These are among matters discussed in the Animal and Plant Health Agency's (APHA's) disease surveillance report for November 2014.
Vet Rec 2015 Mar 21
PMID:Erysipelas in turkeys, sheep and pigs. 2579 78


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