Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0016719 (Friedreich's ataxia)
 2,098 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
frataxin 1111
GAA 386
Mol 185
Frataxin 167
Sep 112
FRDA 88
aconitase 69
axonal 66
ATP 47
ferritin 41
MRI 33
insulin 30
SCA2 28
SCA1 27
histone 24
cysteine desulfurase 23
SCA3 21
histone deacetylase 21
SCA6 20
A-T 17
more...
Disease
Friedreich's ataxia 2098
cardiomyopathy 198
Huntington's disease 134
Alzheimer's disease 109
diabetes 107
Parkinson's disease 104
hypertrophic cardiomyopathy 92
neuropathy 77
amyotrophic lateral sclerosis 66
DM1 63
FRDA 61
vitamin E deficiency 55
Cerebellum 55
iron overload 53
scoliosis 53
hereditary ataxia 52
ATM 50
Charcot-Marie-Tooth disease 44
fragile X syndrome 38
spastic paraplegia 37
more...
Symptom
ataxia 526
cerebellar ataxia 133
dysarthria 75
weakness 44
tremor 27
dystonia 23
spasticity 22
ophthalmoplegia 12
paraparesis 11
anesthesia 11
ataxic gait 10
seizures 10
chorea 10
thinning 9
abnormal gait 7
myoclonus 7
pain 7
hypotonia 7
neurological disability 6
incoordination 5
more...
Drug
TTC 50
vitamin E 41
Idebenone 17
Vitamin E 13
ROS 12
NADH 11
CSF 8
lysine 8
DM1 6
ADM 6
Cardiovasc 5
CTT 5
Posture 4
Heme 4
EPI 4
TAT 3
citric acid 3
Alliance 3
Glutathione 3
Vitamin B12 2
more...
Enzyme
aconitase 69
succinate dehydrogenase 28
IscS 26
complex I 19
pyruvate dehydrogenase 19
diaphorase 16
superoxide dismutase 14
cytochrome oxidase 11
glutathione peroxidase 10
ferrochelatase 10
pyruvate dehydrogenase 10
RNA polymerase 10
pyruvate dehydrogenase 10
pantothenate kinase 9
MPP 8
citrate synthase 8
proteasome 7
catalase 7
ceruloplasmin 7
protein kinase 7
more...
Compound
iron 476
DNA 264
Dec 124
oxygen 104
Clin 96
TTC 50
ATP 47
glucose 46
calcium 33
Cardiol 30
cysteine 26
coenzyme Q10 24
zinc 21
hydrogen 20
copper 18
His 13
GSH 13
GSH 13
Vitamin E 13
NAD 11
more...