Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0016719 (Friedreich's ataxia)
 2,098 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
frataxin 0.429
Frataxin 0.065
GAA 0.048
FRDA 0.028
ISD11 0.002
NFS1 0.002
STM7 0.002
GAA1 0.002
ISCU 0.002
aconitase 0.001
SCA2 0.001
SCA7 0.001
SCA1 0.001
cysteine desulfurase 0.001
SACS 0.001
mitochondrial ferritin 0.001
IscU 0.001
mature T-cell proliferation 1 0.001
SCA3 0.001
SCA6 0.000
IOSCA 0.000
aprataxin 0.000
DRPLA 0.000
FARS 0.000
MTIF2 0.000
H2AFY2 0.000
senataxin 0.000
dentatorubral-pallidoluysian atrophy 0.000
PMPCA 0.000
ATLD 0.000
ALS4 0.000
SPG7 0.000
SCA12 0.000
GLRX5 0.000
PIP5K1B 0.000
ABCB7 0.000
SCA10 0.000
DCYTB 0.000
alpha-tocopherol transfer protein 0.000
lipoic acid-containing protein 0.000
RNF126 0.000
MRS3/4 0.000
pantothenate kinase 0.000
GRX5 0.000
SCA8 0.000
APTX 0.000
Caytaxin 0.000
SANDO 0.000
pitrilysin metallopeptidase 1 0.000
NCLX 0.000
mitoferrin 0.000
MERRF 0.000
CMTX5 0.000
FAD1 0.000
lipoamide dehydrogenase 0.000
SPTBN2 0.000
putative DNA binding protein 0.000
SCA5 0.000
POLG protein 0.000
CT51 0.000
TGM6 0.000
PRKACG 0.000
GRAP 0.000
TSA-1 0.000
SETX 0.000
HEMO 0.000
iron regulatory protein 2 0.000
C10orf2 0.000
ANO10 0.000
KGDHC 0.000
COG5 0.000
lipoamide 0.000
SARA 0.000
SPG3 0.000
muscle creatine kinase 0.000
Hallervorden-Spatz syndrome 0.000
DARS2 0.000
Jac1 0.000
ZO2 0.000
ZFYVE26 0.000
JPH3 0.000
CHCHD4 0.000
SEPW1 0.000
CRIPT 0.000
CCTG 0.000
ferrochelatase 0.000
mitochondrial intermediate peptidase 0.000
mitochondrial aconitase 0.000
MSS4 0.000
MELAS 0.000
ADCK3 0.000
HMSN I 0.000
FAST-1 0.000
AGK 0.000
IkappaB kinase complex-associated protein 0.000
meiotic recombination 11 0.000
SCA17 0.000
ATXN10 0.000
TMEM165 0.000
PDPK1 0.000
Lipoyl synthase 0.000
neurofilament-light 0.000
ferritin-like protein 0.000
TMEM70 0.000
FRAXE 0.000
hephaestin 0.000
P94 0.000
axonal 0.000
transferrin receptor 2 0.000
NARP 0.000
ferritin 0.000
AAT1 0.000
NDUFA1 0.000
A-T 0.000
NifU 0.000
HSAN1 0.000
GBS 0.000
ferroportin 1 0.000
spinocerebellar ataxia type 2 0.000
TTBK2 0.000
fatty acid 2-hydroxylase 0.000
PANK2 0.000
electron transfer flavoprotein-ubiquinone oxidoreductase 0.000
class I histone deacetylase 0.000
ataxin-3 0.000
puratrophin-1 0.000
Glutaredoxin-1 0.000
BCS1L 0.000
SDH2 0.000
3-hydroxy-3-methylglutaryl-CoA lyase 0.000
KCNC3 0.000
EA1 0.000
SIL1 0.000
ELP3 0.000
dihydrolipoamide succinyltransferase 0.000
iron regulatory protein 1 0.000
HADHA 0.000
Barth syndrome 0.000
POLG 0.000
CMT2A 0.000
pyruvate dehydrogenase complex 0.000
Aconitase 0.000
ALAS1 0.000
EA2 0.000
CTP:phosphoethanolamine cytidylyltransferase 0.000
MTP1 0.000
OPA1 0.000
IRP1 0.000
ethanolamine kinase 0.000
MOT 0.000
adenosine monophosphate deaminase 0.000
MSH3 0.000
OPA3 0.000
REEP1 0.000
InsP3R1 0.000
FGF14 0.000
coproporphyrinogen oxidase 0.000
LHON 0.000
Mol 0.000
TR-beta 0.000
more...
Disease
Friedreich's ataxia 0.999
FRDA 0.022
hereditary ataxia 0.008
vitamin E deficiency 0.002
Early Onset Cerebellar Ataxia 0.001
SCA2 0.001
olivopontocerebellar atrophy 0.001
SCA7 0.001
Early onset cerebellar ataxia with retained tendon reflexes 0.001
FRDA2 0.001
SCA6 0.001
SCA1 0.001
cardiomyopathy 0.001
Marie's ataxia 0.001
Cerebellum 0.001
Roussy-Levy 0.001
Huntington's disease 0.001
Temporal pallor 0.001
Gaze palsy 0.001
Machado-Joseph disease 0.001
hypertrophic cardiomyopathy 0.001
IOSCA 0.000
CMT2A2 0.000
Sanger-Brown 0.000
spastic paraplegia 0.000
X-linked sideroblastic anemia 0.000
DM1 0.000
AOA2 0.000
Charcot-Marie-Tooth disease 0.000
ATLD 0.000
SCAE 0.000
HMSN VI 0.000
SCA12 0.000
SCA25 0.000
FRA12A 0.000
Spastic ataxia 0.000
alcoholic cerebellar degeneration 0.000
Spinocerebellar degeneration 0.000
Ocular siderosis 0.000
VED 0.000
iron overload 0.000
mitochondrial disease 0.000
FARR 0.000
SPG7 0.000
SCA5 0.000
degenerative disease 0.000
fragile X syndrome 0.000
SCA16 0.000
SCA23 0.000
sensory neuropathy 0.000
apraxia 0.000
scoliosis 0.000
SANDO 0.000
CMTX5 0.000
Leber's hereditary optic neuropathy 0.000
Duchenne's disease 0.000
sideroblastic anemia 0.000
MERRF 0.000
optic atrophy 0.000
cerebellar syndrome 0.000
SCA8 0.000
neuropathy 0.000
disorders of iron metabolism 0.000
SACS 0.000
amyotrophic lateral sclerosis 0.000
SCA15 0.000
Neuromuscular scoliosis 0.000
Leigh syndrome 0.000
HMSN I 0.000
MILS 0.000
Hypertrophic cardiomyopathy 0.000
ATM 0.000
FRAXE 0.000
SCA28 0.000
Refsum disease 0.000
Parkinson's disease 0.000
SCA4 0.000
MELAS 0.000
Fazio-Londe 0.000
HMSN I 0.000
Herpes zoster oticus 0.000
Andermann syndrome 0.000
SCA14 0.000
hereditary chorea 0.000
MELAS 0.000
Kugelberg-Welander 0.000
allergic rash 0.000
SPG31 0.000
Episodic ataxia 0.000
neuromuscular disorder 0.000
Cerebellar atrophy 0.000
Spinocerebellar ataxia 0.000
SCAN1 0.000
SCA17 0.000
Auditory neuropathy 0.000
Alzheimer's disease 0.000
FRAXA 0.000
MGA3 0.000
ALS4 0.000
Hallervorden-Spatz disease 0.000
OPA3 0.000
Kennedy syndrome 0.000
Kearns-Sayre syndrome 0.000
Barth syndrome 0.000
Thiamine-responsive megaloblastic anemia 0.000
hereditary motor and sensory neuropathy 0.000
Speech impairment 0.000
Keshan disease 0.000
peripheral neuropathy 0.000
hyponasality 0.000
muscular atrophy 0.000
FXTAS 0.000
ventricular hypertrophy 0.000
dilated cardiomyopathy 0.000
Chronic progressive external ophthalmoplegia 0.000
Channelopathies 0.000
Pontocerebellar hypoplasia 0.000
acquired dyslexia 0.000
HSAN1 0.000
myoclonus epilepsy 0.000
thrombopathy 0.000
TGCT 0.000
psycho-organic syndrome 0.000
Complex I deficiency 0.000
HDL1 0.000
white muscle disease 0.000
mitochondrial myopathy 0.000
DM2 0.000
spinal degeneration 0.000
OPA1 0.000
Emery-Dreifuss muscular dystrophy 0.000
multifocal atrial tachycardia 0.000
neurological disease 0.000
Oropharyngeal dysphagia 0.000
tocopherol deficiency 0.000
hereditary hemochromatosis 0.000
disorders of amino acid metabolism 0.000
Upper limb 0.000
hemochromatosis 0.000
Wilson's disease 0.000
diabetes 0.000
HFA 0.000
Wolfram syndrome 0.000
gluten sensitivity 0.000
AOA 0.000
Multiple system atrophy 0.000
PARK6 0.000
retinitis pigmentosa 0.000
McLeod syndrome 0.000
Kufs' disease 0.000
SPG11 0.000
FANCD1 0.000
eye movement disorder 0.000
AAT1 0.000
familial dysautonomia 0.000
hereditary sensory neuropathy 0.000
nystagmus 0.000
protein deficiency 0.000
disorders of carbohydrate metabolism 0.000
restless legs syndrome 0.000
more...
Symptom
ataxia 0.008
cerebellar ataxia 0.002
dysarthria 0.001
poor balance and coordination 0.001
urgent urination 0.000
Ataxic 0.000
ataxic gait 0.000
Pyramidal signs 0.000
spasticity 0.000
dystonia 0.000
chorea 0.000
abnormal gait 0.000
weakness 0.000
neurological disability 0.000
paraparesis 0.000
ophthalmoplegia 0.000
tremor 0.000
inanition 0.000
intention tremor 0.000
exertional chest pain 0.000
impaired motor coordination 0.000
incoordination 0.000
DNA marker 0.000
athetosis 0.000
male subfertility 0.000
myoclonus 0.000
hypotonia 0.000
pallor 0.000
thinning 0.000
loss of balance 0.000
clumsiness 0.000
Gastrointestinal symptoms 0.000
CSR 0.000
clonus 0.000
hyperoxia 0.000
bradykinesia 0.000
hypertonia 0.000
seizures 0.000
asthenia 0.000
anesthesia 0.000
memory loss 0.000
starvation 0.000
apathy 0.000
syncope 0.000
dizziness 0.000
paresthesia 0.000
angina 0.000
ENT 0.000
back pain 0.000
lethargy 0.000
paresis 0.000
nausea 0.000
anorexia 0.000
dyspnea 0.000
analgesia 0.000
collapse 0.000
spasm 0.000
chest pain 0.000
hypercapnia 0.000
headache 0.000
splenomegaly 0.000
discomfort 0.000
discomfort 0.000
sleepiness 0.000
fatigue 0.000
functional recovery 0.000
exhaustion 0.000
abdominal pain 0.000
pain 0.000
respiratory distress 0.000
cough 0.000
overweight 0.000
vomiting 0.000
diarrhea 0.000
Drug
Idebenone 0.001
TTC 0.001
Parnate 0.000
vitamin E 0.000
CTT 0.000
Chantix 0.000
Elm 0.000
Vitamin E 0.000
Tetrofosmin 0.000
Epoetin alfa 0.000
DM1 0.000
Epoetin alfa 0.000
GVG 0.000
Desferal 0.000
ADM 0.000
Desferal 0.000
Exenatide 0.000
Guanidine 0.000
EPI 0.000
Guanidine 0.000
Flunitrazepam 0.000
ROS 0.000
Heme 0.000
Vitamin B12 0.000
TAT 0.000
NADH 0.000
Alliance 0.000
AGG 0.000
Posture 0.000
Gastro 0.000
Estrogens 0.000
Clopidogrel 0.000
CoCl2 0.000
CoCl2 0.000
Methylene blue 0.000
ZnCl2 0.000
ZnCl2 0.000
Glutathione 0.000
FeCl3 0.000
BH4 0.000
CSF 0.000
MgSO4 0.000
Ranitidine 0.000
TAC 0.000
Simvastatin 0.000
Parkin 0.000
Parkin 0.000
Dakar 0.000
TMS 0.000
citric acid 0.000
pyridoxal phosphate 0.000
lysine 0.000
niacin 0.000
Adriamycin 0.000
ICI 0.000
Mutagen 0.000
ROC 0.000
THF 0.000
DNase I 0.000
ENT 0.000
ABC 0.000
Gel 0.000
MAP 0.000
Cardiovasc 0.000
ascorbate 0.000
Enzyme
aconitase 0.001
IscS 0.001
valine dehydrogenase 0.000
pantothenate kinase 0.000
ferrochelatase 0.000
phosphoethanolamine cytidylyltransferase 0.000
diaphorase 0.000
succinate dehydrogenase 0.000
NADH kinase 0.000
pyruvate dehydrogenase 0.000
electron transfer flavoprotein dehydrogenase 0.000
ethanolamine kinase 0.000
dihydrolipoamide succinyltransferase 0.000
3-hydroxy-3-methylglutaryl-CoA lyase 0.000
complex I 0.000
MPP 0.000
coproporphyrinogen oxidase 0.000
pyruvate dehydrogenase 0.000
pyruvate dehydrogenase 0.000
biliverdin reductase 0.000
LipA 0.000
PDH 0.000
Lod 0.000
SCP 0.000
PIP kinase 0.000
citrate synthase 0.000
cytochrome oxidase 0.000
fumarase 0.000
ceruloplasmin 0.000
alpha-ketoglutarate dehydrogenase 0.000
alpha-L-iduronidase 0.000
pyruvate decarboxylase 0.000
biotinidase 0.000
TRS 0.000
lecithin:cholesterol acyltransferase 0.000
isopeptidase 0.000
TAT 0.000
thioredoxin reductase 0.000
acyl-CoA dehydrogenase 0.000
porphobilinogen deaminase 0.000
TOR 0.000
heme oxygenase 0.000
polynucleotide kinase 0.000
glutathione peroxidase 0.000
rhodanese 0.000
glutamate synthase 0.000
ClpP 0.000
glutamate synthase 0.000
acyl-CoA dehydrogenase 0.000
glutamate synthase 0.000
hexosaminidase 0.000
LasR 0.000
delta-aminolevulinic acid dehydratase 0.000
NADH dehydrogenase 0.000
PDK1 0.000
ALA synthase 0.000
superoxide dismutase 0.000
GRK5 0.000
RNA polymerase 0.000
histone acetyltransferase 0.000
RNase H 0.000
DNA polymerase 0.000
pyruvate carboxylase 0.000
proteasome 0.000
botulinum neurotoxin 0.000
adenylate kinase 0.000
malate dehydrogenase 0.000
chaperonin 0.000
MIP 0.000
phosphoglycerate kinase 0.000
pyruvate kinase 0.000
diaphorase 0.000
peroxiredoxin 0.000
DNA ligase 0.000
DNA ligase 0.000
endonuclease 0.000
creatine kinase 0.000
isocitrate dehydrogenase 0.000
thyroid peroxidase 0.000
lipoprotein lipase 0.000
isocitrate dehydrogenase 0.000
catalase 0.000
thymidylate synthase 0.000
phosphofructokinase 0.000
phosphoenolpyruvate carboxykinase 0.000
phosphoenolpyruvate carboxykinase 0.000
glutamate dehydrogenase 0.000
glutamate dehydrogenase 0.000
CAD 0.000
CAD 0.000
glutamate dehydrogenase 0.000
CAD 0.000
ACE 0.000
phosphoenolpyruvate carboxykinase 0.000
protein kinase 0.000
deaminase 0.000
ATPase 0.000
caspase-3 0.000
AMP-activated protein kinase 0.000
dihydrofolate reductase 0.000
GSK 0.000
ATP synthase 0.000
RNase 0.000
MAP 0.000
caspase-9 0.000
glucose-6-phosphate dehydrogenase 0.000
RNase 0.000
ACS 0.000
topoisomerase 0.000
transcriptase 0.000
glutathione reductase 0.000
luciferase 0.000
aspartate aminotransferase 0.000
topoisomerase 0.000
monoamine oxidase 0.000
chymotrypsin 0.000
AMPK 0.000
acid phosphatase 0.000
PARP 0.000
neuraminidase 0.000
beta-galactosidase 0.000
tyrosine hydroxylase 0.000
APC 0.000
peroxidase 0.000
lipase 0.000
phosphodiesterase 0.000
mitogen-activated protein kinase 0.000
alanine aminotransferase 0.000
lactate dehydrogenase 0.000
thrombin 0.000
renin 0.000
focal adhesion kinase 0.000
protein kinase C 0.000
ERK 0.000
Compound
iron 0.001
TTC 0.001
Dyclonine 0.000
Dyclonine 0.000
C7H6N2O3 0.000
coenzyme Q10 0.000
DFH 0.000
2-aminobenzamide 0.000
DNA 0.000
Coenzyme Q10 0.000
Calpeptin 0.000
Choline chloride 0.000
Vitamin E 0.000
Lipozyme 0.000
Diacetoxyscirpenol 0.000
CoQ 0.000
oxygen 0.000
Dimethyl fumarate 0.000
Tranylcypromine 0.000
Emery 0.000
Atracurium 0.000
Sulforaphane 0.000
DFO 0.000
ATP 0.000
Amantadine 0.000
Purine 0.000
ubiquinone 0.000
NFA 0.000
4-phenyl-1,2,3,6-tetrahydropyridine 0.000
PDH 0.000
Desferal 0.000
INN 0.000
AAB 0.000
AAB 0.000
HPT 0.000
BSO 0.000
5-hydroxytryptophan 0.000
Vigabatrin 0.000
Heme 0.000
TBE 0.000
TCC 0.000
cysteine 0.000
Alizarin Red S 0.000
L-carnitine 0.000
TTP 0.000
MAOA 0.000
CAA 0.000
Pyruvate 0.000
Creatine 0.000
benzamide 0.000
SDA 0.000
Flumazenil 0.000
PAPS 0.000
Antimycin 0.000
beta-alanine 0.000
Protoporphyrin IX 0.000
VMA 0.000
Dec 0.000
glucose 0.000
Thiamine 0.000
Bisulfite 0.000
Neuronal 0.000
IPN 0.000
Taurine 0.000
Topiramate 0.000
Isoform 0.000
NADH 0.000
GSSG 0.000
Clin 0.000
TTA 0.000
Tiron 0.000
DDVP 0.000
aspartic acid 0.000
ATC 0.000
NAD 0.000
zinc 0.000
ATC 0.000
HVA 0.000
MPP 0.000
MPP 0.000
phosphocreatine 0.000
pyrimidine 0.000
5-HTP 0.000
isobutyric acid 0.000
pyrimidine 0.000
5-HTP 0.000
Methylene blue 0.000
malonic acid 0.000
aspartic acid 0.000
GSH 0.000
GSH 0.000
aspartic acid 0.000
MCP 0.000
Tumor Necrosis Factor 0.000
DTT 0.000
tetraphosphate 0.000
Pima 0.000
DTT 0.000
Thioredoxin 0.000
Cardiol 0.000
NAD 0.000
H2O2 0.000
Isoflurane 0.000
nicotinamide 0.000
copper 0.000
aspartic acid 0.000
salicylaldehyde 0.000
salicylaldehyde 0.000
salicylaldehyde 0.000
salicylaldehyde 0.000
salicylaldehyde 0.000
salicylaldehyde 0.000
calcium 0.000
Histone 0.000
TBP 0.000
GABA 0.000
delta-aminolevulinic acid 0.000
GABA 0.000
8-OHdG 0.000
HMG-CoA 0.000
5-HIAA 0.000
DPA 0.000
DPA 0.000
DPA 0.000
DPA 0.000
DPA 0.000
TBP 0.000
TRH 0.000
His 0.000
Inositol 0.000
Phosphatidylcholine 0.000
glutamine 0.000
TAA 0.000
Biotin 0.000
GM2 0.000
2-nonenal 0.000
ubiquinol 0.000
Lac 0.000
C2H2 0.000
Hemoglobin 0.000
NADP 0.000
Choline 0.000
2-oxoglutarate 0.000
hydrogen 0.000
selenium 0.000
SPM 0.000
glutamate 0.000
TXA2 0.000
Asp 0.000
25-dihydroxycholecalciferol 0.000
TPP 0.000
MPTP 0.000
GPT 0.000
NTA 0.000
isoleucine 0.000
isoleucine 0.000
TBI 0.000
DIC 0.000
Retinal 0.000
N-acetylcysteine 0.000
more...