Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0016632 (Fox)
 1,461 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A rare case of Morbus Fox-Fordyce in a patient under the hormonal contraceptive pill Trisiston has been reported. Morbus Fox-Fordyce was diagnosed by histological examination after exclusion of other diseases. Six months after beginning of treatment using Norethisterone patient is well.
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PMID:[Case report of Fox-Fordyce disease]. 341 13

Fox-Fordyce disease is an uncommon condition that is biopsied even less commonly. Since the publication of Shelley and Levy, in 1956, the disease is regarded widely to be "apocrine miliaria", an analogue of eccrine miliaria. Histopathologically, an "intraepidermal sweat retention vesicle" is considered the only feature diagnostic of the condition. In this article, the entire literature devoted to the subject and reviewed features clinically and histopathologically as they were presented in those publications. Furthermore, observations in sections of tissue cut from 8 biopsy specimens taken from 4 patients with Fox-Fordyce disease are presented including correlation clinicopathologic. Changes histopathologically in Fox-Fordyce disease vary greatly. Apart from findings described previously as being typical (e.g., dilation, hyperkeratosis, and spongiosis of infundibula), there were vacuolar alteration at the dermo-epithelial junction of infundibula, dyskeratotic cells scattered in infundibula, and parakeratosis in the manner of cornoid lamellation within an orthokeratotic plug filling a dilated infundibulum. Infundibula and apocrine ducts were surrounded by numerous foamy macrophages. Despite that variation of features histopathologically, the appearance clinically, was similar in all patients, namely small infundibulocentric papules, sometimes with a keratotic plug in the center of it, and sometimes with a yellow cast. In conclusion, current concept of Fox-Fordyce disease is too restricted. All the different patterns histopathologically observed by us are manifestations of one single pathologic process named for Fox and Fordyce.
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PMID:Patterns histopathologic of Fox-Fordyce disease. 1561 31

Syringomas are common benign neoplasms encountered mostly around the eyes. However, as described herein, these tumors can occur in atypical locations such as the axilla. The differential diagnosis revolves around those entities more likely seen in this anatomical location (such as Fox-Fordyce, Hailey-Hailey and Darier diseases). Various ablative modalities are curative.
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PMID:Axillary syringomas. 1862 35

The article presents the description of the clinical observation of the patient 28 years old with multiple granulomatous eruptions on the skin of the scrotum, accompanied by itching and pain when walking. Surgical treatment consisted of excising the skin of the scrotum and substitution dermatoplasty was performed. Fox - Fordyce disease was confirmed by histological examination of tissue removed: advanced cystic sebaceous gland duct with calcifications in its lumen was revealed. The were no relapses during follow-up of 15 months.
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PMID:[UROLOGICAL ASPECTS OF THE FOX - FORDYCE DISEASE]. 2609 99

Fox-Fordyce disease is a rare, chronic skin disorder which affects the apocrine areas. This disease is due to the obstruction of the apocrine sweat duct. Extragenital regions are commonly affected than the genital region. We, herein, report a case of Fox-Fordyce in a female, with onset in the fifth decade and involving only the genital region.
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PMID:Fox-Fordyce disease of the vulva. 2719 Apr 15