Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0016382 (flushing)
 6,387 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Vinorelbine is a vesicant associated with extra-vasation hazards and injection site reactions, which can be alleviated by shortening of infusion time and flushing of intravenous fluid. A critical review of the current evidence showed that the optimal administration is to flush >or= 75-124 mL of intravenous fluid after vinorelbine infusion. Intravenous push administration over 1-2 min does not seem to offer significant improvement over rapid intravenous infusion over 6-10 min.
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PMID:Vinorelbine and venous irritation: optimal parenteral administration. 1698 52