Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0016382 (flushing)
 6,387 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

In an earlier project, we identified five alcohol-consumption aftereffect factors, which were named Hangover, Euphoria, Flushing, Seizures, and Sleepiness. In this study (N = 100) we assessed the construct validities of the five, using 47 MMPI, self-report, and recidivism criteria. The number of significant relationships between the factors and the criteria substantially exceeded chance. The Hangover factor related to social maladjustment and to the MMPI Psychopathic Deviate, Paranoia, Psychasthenia, Hypomania, and Masculinity-Femininity scales. The Euphoria factor was associated with a high number of job losses, but a low incidence of certain physical sequelae. The Flushing factor was associated with high consumption, late development of alcoholism, many physical complaints, and older age. The Seizure factor correlated with high consumption, facial puffiness, tremors, and lack of defensiveness on the MMPI. The Sleepiness factor was associated with a good prognosis and several mild MMPI elevations. These findings suggest that the factors may provide the basis for a useful alcoholism subtyping system and that additional research on them should prove fruitful.
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PMID:The construct validity of an aftereffect-based subtyping system for alcoholics. 221 56

Research that deals with the causes of alcoholism has been hampered by the absence of factor analyses that deal specifically with ethanol's aftereffects. We factor analyzed 100 alcoholics' reports of the effects that they experience after alcohol consumption. Five factors emerged--Hangover, Euphoria, Flushing, Seizures, and Sleepiness. They are described and discussed. Future investigators may find them helpful in assessing theories on the etiology of alcoholism and in studies of ethanol's effects on subsets of alcohol abusers.
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PMID:Factor analysis of the aftereffects of drinking in alcoholics. 397 32