Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0016382 (flushing)
 6,387 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The effects of hydrogen sulphide (H(2)S) and isoeugenol exposure on activity, oxygen consumption (VO(2)), ventilation frequency (Vf) and cytochrome c oxidase activity in a teleost fish are reported. In H(2)S (200 microM Na(2)S) exposed animals VO(2) and Vf decreased significantly (both to 40% of resting) after 30 min, concurrent with a loss of equilibrium and narcosis. Post-flushing, VO(2) increased to resting values, but Vf remained depressed (P<0.05) until 30 min of recovery. Subsequently, equilibrium and mobility were regained accompanied by increases in VO(2) (66%) and Vf (15%) between 60-70 min of recovery. Isoeugenol (0.011 g L(-1)) exposed fish reached stage 4-5 of anaesthesia accompanied by decreases (P<0.05) in VO(2) (64%) and Vf (38%) by 35 min. Post-flushing, VO(2) and Vf recovered to resting values, followed by a rise (P<0.05) in VO(2) (45%) and Vf (25%). Overall, VO(2) in relation to the resting rate was reduced in isoeugenol treated animals. Conversely, VO(2) was increased (P<0.05) relative to the resting rate in H(2)S exposed fish. 20 and 200 microM Na(2)S reduced cytochrome c oxidase activity (P<0.05) in skeletal muscle and gill lamellae by between 69 and 97%, while isoeugenol had no effect in any tissue.
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PMID:Oxygen consumption, ventilation frequency and cytochrome c oxidase activity in blue cod (Parapercis colias) exposed to hydrogen sulphide or isoeugenol. 1972 Jan 58