Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0016382 (flushing)
 6,387 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A flow-through system requiring a low flow rate (4-10 ml/minute/aquarium) was developed for rearing tadpoles. This permitted tadpoles to be raised in tap water that had been dechlorinated and acidified. The aquarium consisted of a 7-liter plastic outer shell. A screen-bottomed basket, inserted into the shell, facilitated handling of the tadpoles. A bottom-scraper and flushing system permitted periodic removal of solid wastes.
 ...
PMID:A minimum-volume, flow-through system for rearing frog tadpoles: aquarium. 31 42

This is a preliminary report of our clinical experience with etomidate, a new intravenous non-barbiturate anaesthetic agent. Thirty-two patients undergoing minor surgical procedures were anaesthetized, induction being with etomidate 0.3 mg/kg body weight. Induction was fast and smooth. Twenty-eight per cent of the patients complained of pain at site of injection but the pain disappeared on flushing with water for injection. Following etomidate injection, 37.5 per cent of patients developed myoclonic movements which were usually mild and self-limiting. We were impressed by the relative stability of the cardiovascular and respiratory systems. Etomidate looks promising and further work is in progress on other aspects of this drug.
 ...
PMID:Clinical trial of etomidate. Preliminary observations on a new non-barbiturate induction agent. 31 6

Seventy-two dog kidneys were stored under hypothermia as described by Collins and Sacks between 24 and 72 hr and then transplanted. The immediate function of the kidneys was measured by p-aminohippuric acid and inulin clearances. Twenty-four hr proved to be the maximum safe preservation time with both methods. The immediate function of the kidneys stored under hypothermia could not be improved by the addition of furosemide to the flushing solution. These results were compared with those gained by mechanical perfusion of the organ. Kidney function after 72 hr of hypothermic mechanical perfusion was significantly better than after 24 hr of hypothermic storage.
 ...
PMID:The immediate function of the kidney after 24-to 72-hr preservation. Hypothermic storage versus mechanical perfusion. 32 10

Preservation of cadaveric renal allografts by ice storage and by machine perfusion after a preliminary flush with a hypertonic citrate solution has been compared in a prospective clinical trial between matched pairs of kidneys from the same cadaver donor. Over a two-year period, ice storage after flushing with the new solution gave results comparable with machine perfusion. Times of warm ischaemia and total times of storage were similar in ice-stored and machine-perfused kidneys and averaged about 16 hours. In each group of recipients, more than half of the kidneys had good early function and one-year survival times were also similar.
 ...
PMID:Preservation of cadaver of renal allografts: comparison of ice storage and machine perfusion. 33 67

Recently, there has been growing concern that microbial health hazards can be increased by the use of activated carbon filters in domestic water systems. The present study was undertaken to investigate the effect of carbon filters on the microbial content of water. Results indicated that the microbial content of filtered and unfiltered water increased to about the same level on overnight standing and, in both cases, was reduced by flushing the next day. In addition, the use of activated carbon for the filtration of contaminated well water over a period of 11 weeks had no effect on the total or coliform count. Under use conditions, activated carbon filters were found to have no significant effect on the number of bacteria present in the water.
 ...
PMID:Effect of an activated carbon filter on the microbial quality of water. 33 99

A prospective clinical trial comparing flushing and ice storage using a new hypertonic citrate solution, with machine preservation by continuous perfusion showed early graft function was similar with each method, and preservation times were comparable. Good early function occurred in half the grafts with preservation times up to 24 hours. Graft survival at three and 12 months was similar with each method of preservation. Graft survival at 12 months was worsened by poor early graft function, whereas patient survival at 12 months was unaffected by early function or by the method of preservation.
 ...
PMID:Preservation of cadaveric renal allografts-comparison of flushing and pumping techniques. 34 Nov 31

In a herringbone milking parlour, teat cup liners were deliberately contaminated in turn with Staphylococcus aureus, Escherichia coli, Streptococcus agalactiae and Sterp uberis. Contamination was achieved by filling the liners with milk that contained 10(6) test organisms per ml. After the clusters had been back-flushed with water at 85 degrees C for five seconds, normal swabbing methods failed to recover any contaminating organisms from the teat liners in 56 tests out of 64. After 10 seconds back-flushing no recoveries were made in the same number of tests. The apparatus developed to effect this back-flushing for a particular herringbone parlour is described, with details of its routine use during milking. For a 100-cow herd, the running cost of such equipment using a five-second back-flush is estimated at no more than 4 pounds per week and, in its present form, would not add more than 10 seconds to the total milking time for each cow. Improvements in design of the apparatus, and in milking techniques arising from the routine use of the device, are also considered.
 ...
PMID:Apparatus for pasteurising teat cup liners between cows in a herringbone parlour. 34 97

Methods were developed for procuring phagocytically active macrophages from porcine lung with minimal damage to respiratory tissues. Procedures included anesthetizing, surgically introducing a T-shaped tracheal catheter, and repeatedly flushing the respiratory tract. Macrophages collected in this manner were characterized as to numbers, types, and phagocytic activity, nonselective lavage of the pulmonary airways of unstimulated and stimulated (evoking agent: thioglycolate medium) animals yielded 5 X 10(7) and 11 X 10(7) respiratory cells per pig, respectively. Because sufficient quantities (300 to 600 cells/test) of unstimulated cells were collected, stimulated cells contaminated with thioglycolate were not further tested. Morphologically, unstimulated macrophages were mainly spherical and mononucleated by variable in size, ranging from 9 to 30 micrometer. Culturally, macrophages adhered to plastic or glass surfaces and readily phagocytized fungal spores, staphylococci, and latex particles in an enrichment medium containing greater than or equal to 20% bovine fetal serum. Macrophages failed to replicate during a 3-week maintenance period. The data suggest that porcine phagocytes of the pulmonary system comprise a free-cell population that is a major surface-constitutive part of the luminal surface of the airways.
 ...
PMID:Collection and cultivation of and phagocytosis by pulmonary macrophages obtained from hysterectomy-derived pigs. 34 91

Simple flushing and cold storage of human kidneys for transplantation has not been accepted for preservation times exceeding 24 hours. A prospective study of 25 primary cadaver kidney transplants was performed to evaluate Collins C2 solution for human kidney preservation. Cold storage time was 10 to 23 hours in 14 cases and 26 to 44.5 hours in 11 cases. Seventeen (68%) of the kidneys had immediate, sustained function. The one-month function rate was 88%. There were no significant differences between the 10- to 23-hour and the 26- to 44.5-hour groups with respect to the incidence of first-week dialysis, one-month graft function, or mean lowest serum creatinine value. Human kidney preservation time can be safely extended beyond 24 hours with Collins C2 flushing followed by simple cold storage.
 ...
PMID:Human kidney preservation by flushing with intracellular solution and cold storage. 35 90

Canine kidneys, flushed with either Collins solution or autologous cryoprecipitated plasma, were then stored for 24 hr by either simple cold storage (submersion) in the flushing solution, or by continuous hypothermic pulsatile perfusion with cryoprecipitated plasma. After autotransplantation without contralateral nephrectomy, detailed split renal function studies were carried out immediately as well as 2 and 7 days later. Measurements were made of inulin clearance, maximal transport of p-aminohippurate, reabsorption of sodium, chloride, and glucose, and the reabsorption of free water. Contralateral nephrectomy was performed 7 days after transplantation, following measurement of renal functions on that day, and plasma urea nitrogen and creatinine were measured periodically over the ensuing 3 weeks. Renal function after transplantation was affected very little by the choice of flushing solution, and the course of azotemia that developed following contralateral nephrectomy was the same in all groups. However, the detailed functional measurements showed that during the 7-day period after transplantation, renal function was depressed to a much greater extent in kidneys treated by simple cold storage than in those that had been perfused.
 ...
PMID:Function of autotransplanted kidneys after 24-hour preservation by hypothermic pulsatile perfusion or simple cord storage. 36 May 23


<< Previous 1 2 3 4 5 6 7 8 9 10 Next >>