Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0016382 (flushing)
 6,387 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The contrast agent Iotrolan 300 has potential advantages for bronchography over previous agents in that it can be injected directly through the bronchoscope and it does not obscure bronchoscopic vision or interfere with further bronchoscopic procedures. It was used for selective bronchography in 20 patients with suspected bronchiectasis. Side effects and change in FEV1 and in arterial oxygen saturation were compared in these patients and in 14 patients undergoing bronchoscopy for suspected carcinoma. Thirteen of the 20 patients undergoing bronchography had side effects, mainly headache, nausea, and a feeling of heat or flushing. The fall in FEV1 at four hours (0.3 l) did not differ from the fall in the control group (0.1 l). The fall in arterial oxygen saturation (SaO2) during bronchography (9.4%) did not differ significantly from the fall during bronchoscopy in the control group (6.1%). Iotrolan gave good quality bronchograms, which in all cases provided a diagnosis. Iotrolan appears to be suitable for bronchography by fibreoptic bronchoscope and to be well tolerated.
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PMID:Suitability of and tolerance to Iotrolan 300 in bronchography via the fibreoptic bronchoscope. 240 28

Facial flushing attacks as a Carcinoid syndrome are quite a rare presentation in pulmonary tumorlets and bronchiectasis. We experienced a case in which a 43-year-old woman with bronchiectasis presented to our department with continuous facial flushing attacks for 3 years in the absence of bronchiectasis symptom. Computed tomographic scans revealed bronchiectasis of the left lower lobe and no tumor. A left lower lobectomy was performed, and multiple tumorlets were observed on microscopic examination among the bronchiectasis. Histologic and immunohistochemical examination revealed findings consistent with diffuse tumorlets and bronchiectasis in the lung.
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PMID:Facial flushing due to multifocal tumorlets in the lung with bronchiectasis. 1963 27