Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0016199 (flank pain)
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Human Gene/Protein
NCCT 8.9
ETFA 8.7
paired box protein 8.5
SYT-SSX2 8.3
ARPKD 7.9
HELIOS 7.7
DNA mismatch repair protein 7.5
LPIN1 7.4
Mullerian inhibiting substance 7.4
SLC7A9 7.2
SYT-SSX1 7.1
TTF1 7.1
SLC3A1 7.0
uroplakin III 7.0
leiomyomatosis and renal cell cancer 6.9
papillary renal cell carcinoma 6.9
HA4 6.9
DIP 6.8
CD99 6.7
COL4A4 6.5
PLAP 6.4
TSC 6.4
SYT-SSX 6.3
INI 6.3
Melan-A 6.2
RCC 6.1
cellubrevin 6.0
P63 6.0
TTF-1 5.9
HM3 5.9
EWS 5.8
She 5.7
CK7 5.7
thyroid transcription factor-1 5.7
TCC 5.7
HTN 5.6
MAK 5.6
PAX8 5.6
SDHC 5.5
FMF 5.5
cytokeratin 7 5.5
CK20 5.4
oxytocinase 5.4
SDHA 5.4
NuMA 5.4
PKD2 5.4
AMACR 5.4
cytokeratin 5.4
thyroid transcription factor 1 5.3
PAX2 5.3
Cam 5.3
desmin 5.2
pT1 5.1
chromogranin A 5.1
fumarate hydratase 5.1
class V 5.0
AMBP 5.0
GBM 5.0
M-protein 5.0
histamine H2 receptor 5.0
NSE 4.9
Fli-1 4.8
LAM 4.8
PKD1 4.8
MIB1 4.8
pT3 4.8
PKD 4.8
TFE3 4.8
AE3 4.8
F18 4.7
synaptophysin 4.7
renal amyloidosis 4.6
alpha-galactosidase A 4.6
T12 4.6
AE1 4.6
calretinin 4.5
SDHB 4.5
neurofibromatosis type 1 4.5
FLI1 4.5
EWSR1 4.4
more...
Disease
Acute pyonephrosis 13.8
Tuberculous pyelonephritis 13.8
Non-functioning kidney 13.8
Renal carbuncle 13.8
Scrotal fistula 13.8
blastema predominant Wilms' tumor 13.8
stage II adrenocortical carcinoma 12.8
Upper urinary tract infection 12.8
Loin pain hematuria syndrome 12.2
Ureteral polyps 12.2
Subcutaneous abscess 12.2
Retrocecal appendicitis 12.2
Renal infarction 12.0
Calyceal diverticulum 11.8
epididymorchitis 11.8
renal cell carcinoma stage 11.8
Calyceal diverticulum 11.8
Renal hemorrhage 11.8
Renal hydatid cyst 11.7
Mild hydronephrosis 11.5
Urinary tuberculosis 11.2
Emphysematous pyelitis 11.2
Atypical leiomyoma 11.0
Wilms' tumor stage 11.0
Renal artery dissection 11.0
Perinephric abscess 10.7
ureterolithiasis 10.7
carcinoma of the ureter 10.7
ureterectasis 10.6
Renal tuberculosis 10.6
Splenic lymphoma 10.5
Cystic kidney disease 10.5
Proteus mirabilis infection 10.5
orthostatic proteinuria 10.4
stage I renal cell carcinoma 10.4
Adrenal myelolipoma 10.3
Bilateral hydronephrosis 10.2
Bellini duct carcinoma 10.2
Ureteritis cystica 10.1
APRT*J 10.1
urinary tract neoplasm 10.1
Metanephric adenoma 10.1
Renal artery occlusion 10.0
Xanthogranulomatous pyelonephritis 10.0
Acute pyelonephritis 9.9
Retroperitoneal abscess 9.9
Emphysematous pyelonephritis 9.9
Ascending colon 9.8
pyeloureteritis cystica 9.8
bladder polyp 9.8
Ascending colon 9.8
Retroperitoneum 9.8
Retroperitoneum 9.8
Retroperitoneum 9.8
calicectasis 9.8
hydroureteronephrosis 9.8
Localized amyloidosis 9.8
Renal metastasis 9.7
staghorn calculus 9.7
pyonephrosis 9.7
cancer of the renal pelvis and ureter 9.7
ureteritis 9.6
Renal artery thrombosis 9.4
Idiopathic hypercalciuria 9.4
Urogenital tuberculosis 9.4
hydronephrosis 9.4
pyuria 9.3
Stauffer's syndrome 9.2
Disseminated aspergillosis 9.2
angiomyolipoma 9.1
recurrent pheochromocytoma 9.1
Renal pelvis 9.1
Renal pelvis 9.1
Ureteropelvic junction obstruction 9.1
Ask-Upmark kidney 9.0
Mesoblastic nephroma 9.0
Myelolipoma 8.9
Ureter 8.9
Ureter 8.9
Pulmonary arteriovenous fistula 8.9
more...
Symptom
flank pain 13.8
Musculoskeletal tenderness 12.8
CVA tenderness 12.6
Left flank pain 12.5
nephralgia 11.8
renal colic 10.4
loin pain 9.7
Localized pain 9.1
dysuria 8.9
renal pain 8.8
vaginal itching 8.7
chyluria 8.5
abdominal fullness 7.7
Urinary symptoms 7.6
colic 7.4
dark urine 7.3
urinary frequency 7.2
chills 7.1
bladder pain 6.8
left upper quadrant pain 6.8
thigh pain 6.8
rigors 6.7
oliguria 6.7
iliac fossa pain 6.5
night sweats 6.4
frequent urination 6.4
testicular pain 6.4
leg edema 6.0
abdominal discomfort 5.9
periorbital edema 5.8
acute abdomen 5.8
abdominal pain 5.8
enuresis 5.7
acute low back pain 5.7
non-productive cough 5.7
right lower quadrant pain 5.6
Physical findings 5.4
nausea 5.3
back pain 5.2
nausea and vomiting 5.2
Respiratory symptoms 5.0
acute abdominal pain 4.9
polyuria 4.8
leg pain 4.8
lightheadedness 4.8
vomiting 4.7
decreased appetite 4.6
persistent cough 4.6
tingling 4.5
blurred vision 4.4
shortness of breath 4.3
chronic back pain 4.3
groin pain 4.3
chest tightness 4.2
anorexia 4.2
clubbing 4.0
Ill 4.0
low back pain 3.9
pelvic pain 3.8
numbness 3.8
fever of unknown origin 3.8
discomfort 3.7
productive cough 3.7
cachexia 3.7
epigastric pain 3.7
discomfort 3.6
pain 3.5
syncope 3.5
sore throat 3.4
shoulder pain 3.4
dyspnea 3.2
chest pain 3.2
photophobia 3.2
myalgia 3.1
exertional dyspnea 3.1
constipation 3.1
neuralgia 3.1
hip pain 3.0
cough 3.0
spasm 3.0
more...
Drug
Elmiron 9.7
Pentosan polysulfate sodium 9.5
Calciparine 9.1
Crixivan 8.0
Ranitidine hydrochloride 7.7
Insulin detemir 7.3
Indinavir 6.9
DMSA 6.6
Vena 6.5
Vena 6.5
Diamminedichloroplatinum 6.1
Cidofovir 5.8
Apixaban 5.7
Tuberculin 5.6
Coumadin 5.4
Eculizumab 5.4
Gelfoam 5.3
Iohexol 4.9
AmBisome 4.8
Diphenhydramine 4.8
PPA 4.6
CPM 4.6
Triad 4.6
VCR 4.5
Triad 4.4
CTA 4.4
DDAVP 3.9
DDAVP 3.9
Etoposide 3.7
Hypaque 3.6
Serum albumin 3.6
Vitamin B12 3.6
Scopolamine 3.5
Fluconazole 3.5
BLM 3.4
Vitamin K 3.4
Prednisolone 3.3
Sorafenib 3.3
VCR 3.2
Ranitidine 3.2
Gelatin 3.1
Dakar 2.8
Nephron 2.6
Imatinib 2.5
HCG 2.5
IFN-beta 2.3
ADM 2.2
Taxol 2.2
CTX 2.1
Nephron 2.0
Spectrum 1.8
ABC 1.7
Angiotensin II 1.5
ampicillin 1.4
CTX 1.4
CTX 1.3
CAM 1.3
citric acid 0.6
Cardiovasc 0.2
Leaf -0.6
Dial -1.1
CSF -1.1
lysine -2.0
Enzyme
adenine phosphoribosyltransferase 6.4
PMT 5.2
CPM 4.4
enolase 4.0
fumarase 3.7
urokinase-type plasminogen activator 3.3
alpha-galactosidase 3.1
lactate dehydrogenase 2.7
CD10 2.6
hypoxanthine-guanine phosphoribosyltransferase 2.5
MDP 2.4
asparaginase 2.4
tissue plasminogen activator 2.4
prostate-specific antigen 2.1
urease 2.0
carbonic anhydrase 2.0
urease 2.0
renin 1.9
neutrophil elastase 1.8
succinate dehydrogenase 1.8
PAH 1.7
thromboplastin 1.7
beta-lactamase 1.7
hyaluronidase 1.7
lipase 1.6
MIP 1.6
kallikrein 1.3
AST 1.3
hyaluronidase 1.2
creatine kinase 1.2
aspartate aminotransferase 1.0
alanine aminotransferase 0.7
plasmin 0.7
elastase 0.7
ACE 0.7
chymotrypsin 0.4
tyrosine hydroxylase -0.0
reverse transcriptase -0.1
APC -0.2
calcineurin -0.2
lysozyme -0.6
peroxidase -0.6
ERK -1.1
trypsin -1.5
alkaline phosphatase -1.7
catalase -1.9
ACS -2.4
Compound
Indinavir sulfate 11.5
Urovision 11.5
Suprofen 9.4
Carboquone 8.8
Carboquone 8.5
Carboquone 8.5
Carboquone 8.5
Carboquone 8.5
Hippuran 8.0
Tienilic acid 7.8
5-methyltryptophan 7.0
Indinavir 6.9
Tamsulosin 6.9
A 150 6.8
A 71 6.5
Cephalothin 6.3
Cystine 6.1
TSC 6.1
Tegafur 6.0
Cidofovir 5.9
A 42 5.8
TCC 5.6
Cystine 5.4
Meperidine 5.4
Tegafur 5.3
Methysergide 5.2
PMT 5.2
o,p'-DDD 5.2
Adrenal 5.2
Tranexamic acid 5.0
Ceftriaxone 5.0
AME 4.8
Ifosfamide 4.8
Diclofenac 4.8
Danazol 4.7
Topiramate 4.6
Vinblastine 4.5
ANCA 4.5
MAK 4.5
oxalate 4.5
Warfarin 4.5
Albendazole 4.4
Clarithromycin 4.4
PPA 4.4
CBDCA 4.4
CBDCA 4.4
Isoproterenol 4.3
creatinine 4.1
Acetazolamide 4.1
CAN 4.1
Octreotide 3.9
PID 3.8
Heparin 3.7
Vitamin K 3.6
Hypaque 3.5
Salix 3.4
PPA 3.4
DTPA 3.4
BLM 3.4
HPP 3.3
DHA 3.3
Prednisolone 3.3
TMA 3.3
AHA 3.3
TMA 3.3
PIN 3.2
DHA 3.2
SCC 3.2
TAP 3.1
DHA 3.1
Heme 3.0
T11 3.0
Abbott 2.9
A 3 2.9
His 2.8
Rifampicin 2.8
APS 2.8
Ketamine 2.7
barium 2.6
T10 2.6
more...