Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0016199 (flank pain)
 2,189 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Schwannomas (also known as Neurilemomas or Neurinomas) are benign tumors of the nervous system that originate in the neural sheath and most commonly occur as solitary encapsulated subcutaneous tumors in otherwise healthy individuals. When they present as multiple tumors, they are histologically indistinguishable from the solitary tumors and, in such a case, they may be associated with neurofibromatosis 2 (NF2) in which the sensory roots of the cranial and spinal nerves are affected more often than the motor roots and the hallmark tumor of which is a vestibular schwannoma (also known as acoustic neuroma). They also may exist as a distinct clinical entity without any stigmata of neurofibromatosis known as schwannomatosis. Generally, schwannomas are less than 5 cm in diameter but sizes greater than 14 cm have been reported. They present as slow growing masses and may present with pain or neurological symptoms. Here we report a patient with sympathetic schwannoma who presented with right flank pain.
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PMID:Sympathetic schwannoma: a case report. 1046 9

A 30-year-old woman, who had a type I neurofibromatosis, visited our hospital with a complaint of left flank pain. Computed tomography revealed a heterogenous solid mass, 12 x 7 x 6 cm in diameter, in the anterior renal region, which was suspected to be a benign retroperitoneal tumor. We performed laparoscopic resection of the tumor because of persisting left flank pain. Pathological diagnosis of the surgical specimen was neurofibroma. The postoperative course was uneventful. The diagnosis and laparoscopic management of retroperitoneal neurofibroma are discussed.
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PMID:[A case of retroperitoneal neurofibroma successfully resected laparoscopically]. 1958 61

Primary malignant peripheral nerve sheath tumor (MPNST) in a young female patient, not associated with neurofibromatosis type-I is extremely rare in the liver. A 33-year-old female was admitted with a right flank pain for a weak. The CT scan showed 12.5-cm-sized mass located at the right hepatic lobe. At laparotomy, about 20.0-cm-sized mass was on the right hepatic lobe with attachment to right diaphragmatic pleura. Right hepatic lobe and adherent part of diaphragmatic pleura were resected. On histology and immunohistochemistry, it was diagnosed MPNST. Adjuvant radiotherapy for the right diaphragmatic pleura and adjuvant chemotherapy with adriamycin, ifosfamide and cisplatin were sequentially performed. The prognosis of MPNST is generally poor and it is associated with a highly aggressive course of recurrence, metastases, and death. Our case is probably a first report about combination therapy.
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PMID:Primary hepatic malignant peripheral nerve sheath tumor successfully treated with combination therapy: a case report and literature review. 2790 56