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Target Concepts:
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Query: UMLS:C0016199 (
flank pain
)
2,189
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Primary renal squamous cell carcinoma is a very rare malignancy of the upper urinary tract. Most patients have history of chronic urolithiasis, analgesics abuse, radiotherapy or infection. Co-existence of
SCC
with xanthogranulomatous pyelonephritis is exceedingly rare with only few reports in the literature. We report a case of a 60-year-old male presented with right
flank pain
and mild tenderness of abdomen. Computed tomography of the abdomen revealed gross hydronephrosis with parenchymal thinning and irregular thick enhancing wall of pelvicalyceal system with multiple calculi in right kidney. Right renal vein appeared distended, filled with hypo dense material. Right nephrectomy was performed and sent for pathological examination. Histological evaluation revealed keratinizing squamous cell carcinoma with infiltration of renal vein and xanthogranulomatous pyelonephritis.
...
PMID:Rare Co-existence of Squamous Cell Carcinoma with Infiltration of Renal Vein and Xanthogranulomatous Pyelonephritis. 2681 4
Chronic nephrolithiasis predisposes to squamous metaplasia and subsequently
SCC
which is a rare malignancy of the upper urinary tract. A 60-year-old woman with a long standing history of renal calculi presented with
flank pain
and fever. Investigations revealed a mass in the superior pole of a non functioning left kidney while the right kidney was sub optimally functioning, hydronephrotic and there was presence of bilateral staghorn calculi. Patient underwent decompression of right kidney by double j stenting and left radical nephrectomy that revealed well differentiated squamous cell carcinoma of renal pelvis. Most
SCC
of the renal pelvis present with advanced disease and dismal prognosis while our patient presented with localized disease without lymphatic and distant metastasis. Thus radical nephrectomy can be curative if the disease can be diagnosed at an earlier stage. This emphasizes the need of early treatment of nephrolithiasis to prevent the development of
SCC
and screening of patients with long standing staghorn calculi.
...
PMID:Squamous Cell Carcinoma of the Renal Pelvis, A Rare Site for a Commonly Known Malignancy. 2689 22
