Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0016199 (flank pain)
 2,189 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Presented is a case report of spontaneous rupture of the renal parenchyma associated with urinoma. A 3-year-old boy had a history of transient gross hematuria followed by sudden onset of left flank pain. Echograms and computed tomographic (CT) scan revealed a left hydronephrotic kidney with perirenal urinoma which had a cyclic change in size corresponding to the pain. Left retrograde pyelogram showed stenosis of the ureteropelvic junction without extravasation of contrast medium. A pin-hole tear was detected in the middle of the left renal parenchyma on exploratory surgery. Left pyeloplasty and retroperitoneal drainage were performed. The postoperative course was satisfactory. Spontaneous rupture of the renal parenchyma, which is frequently caused by renal tumor, vascular disease and/or infection, seems to be seldom caused by increased renal intrapelvic pressure as in rupture of the renal pelvis.
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PMID:[Spontaneous rupture of the hydronephrotic renal parenchyma associated with urinoma in a child]. 802 64

We experienced a case of peripelvic extravasation after extracorporeal shock wave lithotripsy (ESWL) treatment. A 62-year-old man was admitted to our hospital with a complaint of macroscopic hematuria. The patient was diagnosed as having a radiolucent stone in the right kidney and ESWL treatment was performed to focus the stone by using drip infusion pyelography (DIP) under epidural anesthesia. The patient had right flank pain two weeks after ESWL treatment. DIP and computerized tomography (CT) showed peripelvic extravasation of contrast medium. Right pain improved after a double-J catheter was placed for decreasing intra-pelvic pressure. As a result, the disappearance of peripelvic extravasation was recognized by DIP and CT. We reviewed four cases of peripelvic extravasation after ESWL treatment including our case in the Japanese literatures and discussed the cause of peripelvic extravasation after ESWL treatment.
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PMID:[Peripelvic extravasation after extracorporeal shock wave lithotripsy: a case report]. 810 75

Acute renal failure after exercise with frank pain and patchy renal vasoconstriction is a clinical syndrome that occurs in young, previously healthy persons. The authors describe a 24-year-old man who had this syndrome. CT scan showed wedge-shaped contrast enhancement of both kidneys, which suggested patchy renal vasoconstriction. Tc-99m MDP imaging revealed diffuse increased uptake of both kidneys. After renal function was improved, Tc-99m MDP imaging showed normal uptake of both kidneys. Acute renal failure due to acute tubular necrosis was confirmed by renal biopsy. The authors conclude that Tc-99m MDP may be useful in evaluation of acute renal failure after exercise with flank pain and patchy renal vasoconstriction due to acute tubular necrosis.
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PMID:Diffuse increased renal uptake on bone scintigraphy in acute tubular necrosis. 813 77

A 48-year-old male experienced sudden pain in the right flank and macrohematuria with subsequent repeated episodes of painless macrohematuria. In the radiological work-up, CT was interpreted as inflammatory enlargement of the right kidney and MRI diagnosed renal vein thrombosis. There was some suspicion that there might be a malignancy. Five months later the patient had to be admitted to the hospital, because of increasing flank pain, desiccation and general signs of inflammatory disease. Radiological changes compatible with pulmonary metastases were found. Biopsy of enlarged mediastinal lymph nodes revealed undifferentiated carcinoma. Because of the expression of Cytokeratin primary urothelial carcinoma was suspected. The patient then deteriorated rapidly. No further specific therapy could be carried out. Death was chiefly caused by respiratory insufficiency 5 months after the first episode of pain and 1 month after admission. Autopsy revealed a poorly differentiated urothelial carcinoma of the right renal pelvis, with extensive carcinomatous angiomatosis and metastases to the left kidney, lungs, and regional and mediastinal lymph nodes. Independently of the carcinoma, both kidneys also showed interstitial nephritis, papillary necrosis and capillarosclerosis, compatible with analgesic-user kidney ("phenacetin kidney") in the absence of a corresponding history.
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PMID:[Explosive metastasis of a cancer of the kidney pelvis in analgesic kidney]. 815 79

A 44 year old man complained of a left flank pain. The epidural block was performed. After two hours he suddenly experienced severe back pain, lower limb numbness and weakness of the legs. The physical examination revealed the flaccid paraplegia and the disturbance of pain and touch sensation. But his proprioceptive sensation was preserved. The paraplegia gradually disappeared and he had no neurological deficit. Judging from the unique sensory disturbance, the anterior spinal artery syndrome was suspected.
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PMID:[Transient paraplegia following the epidural block]. 818 89

Two cases of arteriovenous malformation of the kidney were reported. The first case was a 19-year-old female, complaining of right flank pain and gross hematuria. Right selective renal arteriography revealed a 2 x 1.5 cm large cisoid type arteriovenous malformation at the most distal region of the lower branch of the renal artery. Transcatheter embolization, using Gelfoam and absolute ethanol, was successfully done, which was confirmed with repeated digital subtraction angiography with carbon dioxide (CO2-DSA). The second patient was a 55-year-old female with past history of right idiopathic renal bleeding, complaining of right flank colicky pain and gross hematuria. Right selective renal arteriography was done without any pathological findings, while CO2-DSA documented an arteriovenous malformation in the hilar region. Transcatheter embolization was not done, because the malformation seemed to be proximally located. Thus CO2-DSA was thought to be a reliable method in the diagnosis of arteriovenous fistula.
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PMID:[Congenital arteriovenous malformation of the kidney: report of two cases--detection by digital subtraction angiography with carbon dioxide]. 821 76

LPHS is a disorder of obscure etiology and inconsistent pathology whose most prominent clinical feature is severe flank pain. Were it not for the hematuria which nearly always accompanies the pain, there would be no specific objective correlate of the syndrome. In this sense, it is similar to a number of chronic conditions which have inspired heated controversy about their very existence as discrete diseases. As the foregoing discussion of pathogenesis, pathology and diagnosis illustrates, with respect to two important characteristics of a 'prototypical' disease--specificity and mechanism--LPHS falls far short. This, coupled with a rather unimpressive 'visible' concomitant of the symptoms (hematuria), has inspired skepticism and even suspicion in some physicians confronted with the demands for analgesia by these patients. On the part of physicians who have been involved in the care of these patients over time, however, there is no doubt that they suffer from a bona fide illness, if not a disease. The severity of the illness is evinced by the rather extreme measures that have been taken in its treatment; e.g., surgical denervation of the kidney, nephrectomy, autotransplantation. Only the last of these appears to offer the hope of enduring pain relief while preserving renal function, but the risk of pain recurrence in the autograft may limit the usefulness of this procedure. Accordingly, narcotic analgesics may need to be the treatment of first and last resort. Development of specific treatment will depend upon elucidating the pathogenesis of the disorder. The available data suggest further investigation of the role of vasoactive mediators, and the coagulation and immune systems.
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PMID:Loin pain hematuria syndrome. 826 18

A patient is described in whom retroperitoneal fibrosis manifested itself by bleeding from ruptured varices and pain in the left flank and lumbar region. The clinical diagnosis was confirmed by axial computerized tomography and MRI, while the histology from a mesenteric biopsy taken during splenectomy was considered insufficiently consistent with the diagnosis of retroperitoneal fibrosis. Treatment with prednisone resulted in relief of lumbar and flank pain a well as in prevention of further digestive tract hemorrhage. A review of the literature since 1966 shows 16 articles describing the association of retroperitoneal fibrosis and portal hypertension manifesting itself by hemorrhage from bleeding varices.
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PMID:[Retroperitoneal fibrosis and portal hypertension]. 842 76

Retroperitoneal hematoma (RPH) following cardiac catheterization is an infrequent (0.15% incidence) but morbid complication. During a 13-month study period, 11 patients with a significant RPH requiring operative intervention were identified. The mean transfusion requirement was 8.7 units, with two deaths as a consequence of their RPH. Adjunctive cardiac procedures included percutaneous transluminal coronary angioplasty (five), stent placement (one), and thrombolysis (two). Two patients had RPH following aortography. Suspicion of RPH was most frequently prompted by a falling hematocrit (73%), with hypovolemic shock (systolic blood pressure < 90) in 64%. Lower quadrant or flank pain occurred in four patients. Lower extremity pain occurred in five patients due to femoral nerve compression. Of six patients with a preoperative femoral nerve palsy, complete resolution occurred in four cases. RPH following femoral arterial puncture is a cause of significant morbidity, particularly in the anticoagulated patient. Postcatheterization anticoagulation and high arterial puncture were the principal risk factors (p < 0.001). Early recognition is essential and should be prompted by a falling hematocrit, lower abdominal pain, or neurological changes in the lower extremity. There should be a low threshold for performing abdominopelvic CT scans in such patients. Management of RPH must be individualized: 1) patients with neurological deficits in the ipsilateral extremity require urgent decompression of the hematoma, 2) anticoagulation should be stopped or minimized, 3) hematoma progression by serial CT necessitates surgical evacuation and repair of the arterial puncture site.
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PMID:Retroperitoneal hematoma following femoral arterial catheterization: a serious and often fatal complication. 847 49

From 1984 to 1989 35 patients presented with uncharacteristic flank pain or recurrent urinary tract infections and small nonobstructing caliceal calculi. Thirty patients were treated; 13 with percutaneous stone extraction, 8 with extracorporeal shock wave lithotripsy, 3 with ureteroscopic stone manipulation and 2 by open surgery. Stone removal was successful in 39 patients and they were all relieved of their symptoms (86%). Stone size was decreased in 2 patients who felt a marked alleviation. Where the stone remained unaffected the symptoms persisted unabated. These observations suggest that small caliceal stones can cause pain. The results of treatment are such that it is justifiable to treat a small caliceal stone in patient suffering from flank pain of no other known cause.
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PMID:Painful caliceal calculi. The treatment of small nonobstructing caliceal calculi in patients with symptoms. 849 73


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