Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0016199 (flank pain)
 2,189 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A case of Wilms' tumor in an adult patient is presented. The tumor in adults is rather rare and has an unfavorable prognosis. A 39-year-old man bruised his left flank while skiing in February, 1983. He noticed severe left flank pain. The pain subsided after a week of rest. However, he complained of left abdominal mass and dull pain again, and consulted our outpatient clinic on May 21, 1983. Left transperitoneal nephrectomy was performed under a diagnosis of left injured renal tumor. Histological diagnosis was nephroblastoma. A combined chemotherapy of actinomycin D (ACD) and vincristine (VCR) was started after operation. A total of 10 mg of ACD and 14 mg of VCR was administered by the end of 1983. In March 1984, however, a local recurrence and pulmonary metastases of the tumor were detected by CT and chest films. Local RF-hyperthermia combined with irradiation, alpha-interferon or chemotherapy using cisplatin and adriamycin was given. The patient died of profound cachexia in December, 1984 after gradual deterioration of general conditions.
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PMID:[Wilms' tumor in an adult patient: a case report]. 303 7

Idiopathic hypercalciuria (IH) in adults is recognized as a cause of urolithiasis. If IH is symptomatic, the symptoms are hematuria, renal colic, or obstructive uropathy with or without infection. In children, IH has been linked to the spectrum of urinary symptoms including hematuria, pyuria, dysuria, recurrent urinary infections, abdominal or suprapubic pain, proteinuria, and the frequency-urgency syndrome. Hematuria may appear prior to the appearance of stones, and thiazide therapy appears to prevent stone formation by decreasing urinary calcium excretion. This report describes an older adolescent with hematuria and flank pain. His urinary chemistry values were not consistently typical of IH, but a thiazide trial with withdrawal challenge was diagnostic. His case is remarkable because, though essentially an adult, his disease was typical of prepubertal disease. Adolescents with unexplained urinary symptoms should be evaluated for IH. The urinary calcium-creatinine ratio may not be elevated, and timed urinary calcium may be equivocal. In some cases a thiazide trial may be valuable and cost effective.
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PMID:Atypical idiopathic hypercalciuria in an adolescent. 318 67

Of 446 patients treated by extracorporeal shock wave lithotripsy 22 had small nonobstructive caliceal stones associated with lumbar or flank pain. Size (less than 1 cm.) and location of the stone did not explain the severity of the symptoms, nor would they have been an indication for open or percutaneous stone removal. Followup consisted of a sonogram and a film of the kidneys, ureters and bladder on postoperative day 1, a film of the kidneys, ureters and bladder 2 weeks after treatment, and a film of the kidneys, ureters and bladder and/or excretory urography after 3 months for patients with residual stone fragments. All patients were interviewed 3 to 15 months after treatment to ascertain the resolution or persistence of the symptoms. After extracorporeal shock wave lithotripsy, 3 of 22 patients had persistent stone fragments for more than 3 months: 2 reported no change and 1 had marked improvement of the symptoms. Of the remaining 19 patients 15 (79 per cent) had complete resolution of the pain and 4 (21 per cent) had significant symptomatic improvement. Thus, 20 of 22 patients (91 per cent) achieved complete or significant relief of pain. The only complication was a perirenal hematoma that resolved spontaneously. These results indicate that small, nonobstructive caliceal stones can be responsible for persistent, severe flank pain. Extracorporeal shock wave lithotripsy is an effective, noninvasive treatment for caliceal stones and it can be justified as therapeutic treatment when the correlation between a small caliceal stone and persistent flank pain is indeterminable.
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PMID:Small caliceal stones: is extracorporeal shock wave lithotripsy justified? 336 60

The value of herniography was reviewed in 45 patients with a variety of urological symptoms (4 with flank pain, 20 with pain from the funicle or scrotum, 11 with symptoms simulating prostatitis and 10 with ill-defined symptoms from the small pelvis). In no patient was a groin hernia palpable at physical examination. However, herniography revealed an inguinal hernia in 6 patients who underwent herniorrhaphy, whereafter 5 became asymptomatic. We recommend herniography in patients with long-standing obscure groin pain to reveal the presence of a nonpalpable inguinal hernia.
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PMID:Inguinal hernia in urological patients: the value of herniography. 337 96

Suprofen as well as codeine have been shown to be effective analgesics. In this study, a 200-mg suprofen/60-mg codeine dose is scored for analgesic efficacy and safety compared to suprofen (200 mg), codeine (60 mg), and placebo. One hundred sixty-five healthy, adult patients were asked to rate degree of pain experienced over a six-hour period after medication. The combination treatment was found to offer maximum pain relief. Dentists should be aware that flank pain and renal function abnormalities have been reported in postmarketing surveillance.
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PMID:A clinical trial in oral surgery of the analgesic efficacy of a suprofen/codeine combination. 347 17

Anecdotal reports of chronic contained rupture of abdominal aortic aneurysms exist. Their existence and implications have been largely ignored. From March 1984 to March 1985, 24 patients required repair of an infrarenal abdominal aortic aneurysm. Four patients underwent emergent repair. The remaining 20 patients were evaluated with computed tomography electively. Seven patients (35%) were demonstrated to have a rupture of the aneurysm and a retroperitoneal hematoma on the computed tomographic scan. All of the patients had histories of back or flank pain; five patients continued to complain of mild pain on admission. In no case was shock, impending shock, or a decrease in the hemoglobin level present on admission. All patients were operated on within 24 hours of evaluation. At operation, rupture was noted with organized hematoma outside the aorta contained in a pseudoaneurysmal wall of retroperitoneal connective tissue. There was no intraperitoneal blood. There was no operative mortality and survival was 100% at six months. The CT scan evaluation had identified a subgroup of patients with aneurysms associated with chronic contained rupture.
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PMID:Chronic contained rupture of abdominal aortic aneurysms. 370 32

In a study of bacteriuria in elderly (mean age 85 years, range 69 to 101), mostly middle- and upper-class Jewish subjects, attempts were made to determine if bacteriuria without dysuria is otherwise asymptomatic. Seventy-two subjects (59 women and 13 men) without dysuria were questioned about other urinary symptoms (incontinence, frequency, urgency, suprapubic pain, flank pain, fever) and symptoms indicating a lack of well-being (anorexia, difficulty in falling asleep, difficulty in staying asleep, fatigue, malaise, weakness) when they were with and without bacteriuria. Twenty-two subjects had bacteriuria that resolved spontaneously; bacteriuria subsequently developed in 24 nonbacteriuric subjects; and 26 subjects had bacteriuria that resolved with antimicrobial therapy. Subjects occasionally reported urinary symptoms (especially incontinence) and commonly reported symptoms indicating a lack of well-being when they were with and/or without bacteriuria. However, no differences in symptoms were found when bacteriuric subjects were compared with themselves when they were nonbacteriuric. Thus, bacteriuria without dysuria in the elderly appears to be asymptomatic.
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PMID:Lack of association between bacteriuria and symptoms in the elderly. 379 58

A prospective study compared the diagnostic accuracy of sonography and excretory urography in determining the cause of acute flank pain in 61 patients. Forty-one patients had urinary tract stone disease. Of these, five had nonobstructing renal stones and 36 had obstructing stones. A correct diagnosis was made by urography in 85% and by sonography in 66%. Small stones at the ureterovesical junction were more accurately diagnosed by sonography (79%) than by urography (68%). In all the patients where sonography failed to detect the offending stone, the stone was calcified and evident on the plain radiographs. There were no false-positive diagnoses in the patients clinically judged to have passed a renal stone (nine patients) or whose pain was arising outside of the urinary tract (five patients). Neither sonography (17%) nor urography (50%) was accurate in diagnosing acute pyelonephritis in the six patients with this diagnosis. Although sonography is not as accurate overall as urography in acute flank pain, it is a viable alternative in those with recurrent renal colic due to stone disease and in the pregnant patient.
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PMID:Sonography vs. excretory urography in acute flank pain. 389 Apr 87

The value of ultrasound and 131-Hippuran renography for diagnosing hydronephrosis during pregnancy was investigated. In a control series of 31 symptom-free pregnant women the ultrasonographically measured renal pelvic diameters in the three trimesters were 5, 10 and 12 mm on the right side and 3, 4 and 5 on the left, respectively. In ten healthy non-pregnant women the pelvic diameter varied from 3 to 9 mm on the right side and from 2 to 6 mm on the left side when measured during antidiuresis and water diuresis. Out of 35 pregnant women complaining of flank pain, 31 showed an increased renal pelvic diameter. These 35 women also underwent renography on the same day as the ultrasound examination. In 6 of 27 pregnant women with right-sided pain and in 3 of 8 with left-sided pain, diuresis renography indicated acute ureteral obstruction and in 6 of these 9 patients impairment of renal parenchymal function was also evident. In some cases the impaired renal function was fully reversed after surgical intervention. It is concluded that ultrasound investigation of the kidney is a valuable method for screening prior to renography. Since the negative prediction value of using 17 mm as the upper limit of the pelvic diameter was 100%, patients with a smaller pelvic diameter may not need to be referred further for renography or urography, and radiation will thus be minimized. On the other hand, renography is indicated when the pelvic diameter is more than 17 mm in patients complaining of flank pain.(ABSTRACT TRUNCATED AT 250 WORDS)
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PMID:Evaluation of hydronephrosis in pregnancy using ultrasound and renography. 391 76

Renal arterial embolization is often used in the treatment of patients with renal cell carcinoma, either preoperatively to facilitate nephrectomy or as palliative therapy in advanced cases. Eighteen patients (18/58; 31%) underwent renal arterial embolization in our department since 1979, initial 10 cases with Gelfoam and steel coil (group G) and recent 8 cases with absolute ethanol (group A). Clinical studies of daily changes of symptoms and blood chemistry in both groups after embolization were compared and the results were as follows: Severe flank pain was noted immediately after embolization but thereafter well controlled without analgesics in group A. The patients in group G experienced no pain during the procedure of embolization but have had moderate flank pain of two or three days' duration with nausea and/or vomiting and required surgical procedure within a few days after embolization. Post embolization fever in group A was described as higher than that in group G significantly. Leukocytosis was noted to be persistent for up to seven days and blood chemistry showed transient marked elevations of GOT, GPT and LDH immediately after the procedure without significant value in both groups. Embolization to advanced tumor with many parasitic vessels or massive local invasion may not always be available for remaining of viable-appearing tumor cells in venous lumen, as if palliative treatment. Absolute ethanol may be more useful as the embolizing substance than Gelfoam and steel coil by reason of producing wide severe infarction of diseased kidney. Broad marked infarction due to renal arterial embolization may make pathological diagnosis difficult. Immunological effects of renal arterial embolization were not observed in short term patients survival.(ABSTRACT TRUNCATED AT 250 WORDS)
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PMID:[Renal arterial embolization for renal cell carcinoma]. 402 78


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