Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0016199 (flank pain)
 2,189 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A case of giant renal hamartoma considered as congenital mesoblastic nephroma in an adult is reported. A 24-year-old woman was admitted to our hospital with complaints of macroscopic hematuria and left flank pain. On clinical examination, a large left renal tumor was recognized and radical left nephrectomy was performed. The tumor weighed 2,500 g. On histological examination, the tumor was composed of spindle-shaped cells, that were considered as fibroblasts, surrounded by abundant collagenous interstitial material, and many cystic or tubular structures lined by cuboidal epithelium were also seen in the peripheral region. Because of histological similarity we considered this tumor as congenital mesoblastic nephroma in an adult.
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PMID:[A case of giant renal hamartoma considered as congenital mesoblastic nephroma of adult]. 255 52

A 35-year old man was hospitalized for left flank pain. IVP showed left non-visualizing kidney with multiple renal calculi. Selective renal arteriogram revealed avascular mass in the left upper pole. The upper calyx was irregularly distorted. Left nephrectomy was carried out. Grossly, the upper pole was replaced by whitish, firm and homogeneous tumor, which was 7 X 7 cm in diameter and protruded into the upper calyx. Histologically, the tumor was composed of both epithelial and mesenchymal components. The epithelial elements consisted of cysts and tubules, and the mesenchymal elements of loosely textured fibroblasts and smooth muscle cells. Other elements could not be identified. This case was diagnosed as renal hamartoma histologically resembling congenital mesoblastic nephroma of infancy. Congenital mesoblastic nephroma is rare in adults. Continued maturation may finally transform it either to benign mixed tumor as in our case or fibromatous tumor if stroma matures dominantly.
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PMID:[A case of adult renal hamartoma resembling congenital mesoblastic nephroma]. 383 22

A 34-year old woman was admitted for bilateral flank pain, maleolary and palpebral oedema with an insidious evolution lasting for 5 years. Urogram showed a left ureteral duplicity and a right lacunary pelvic image. MRI and echography indicated the complete modification as a renal structure as well as the presence of some bilateral tumoral formations with a nonhomogenous structure, blood diffusion and adenopathy of the renal hilum. Nephrectomy revealed white-gray tumoral nodular tumours. The histopathological test evidenced proliferations of leiomyofibromatous, angiomatous, lipomatous, cartilaginous types with a benign aspect suggesting the diagnosis of a renal dysembryoplasic tumor (hamartoma).
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PMID:Morphopathological and clinical diagnosis aspects of a bilateral dysembryoplasic renal tumor associated with Bourneville's tuberous sclerosis. 916 70

In the general population, tuberous sclerosis-associated renal angiomyolipoma (RAML) is a rare benign hamartoma with potentially life-threatening complications and a poor prognosis. The two patients reported in the present study, who were diagnosed with bilateral RAML and spontaneous rupture of the RAML with tuberous sclerosis, presented with flank pain, abdominal pain, hemorrhage, hematuria and multiple lesions. The two cases are representative examples of the disease, and highlight the importance of determining the risk of acute hemorrhage in the early stages, and the significance of timely and proper treatment.
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PMID:Tuberous sclerosis-associated renal angiomyolipoma: A report of two cases and review of the literature. 2904 2