Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0016199 (flank pain)
 2,189 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Infarction with or without torsion of the greater omentum is an uncommon but well recognised acute abdominal condition which was seldom diagnosed preoperatively before the widespread clinical use of US and CT. The aetiology is unknown and speculative. In most cases the pathology is right sided and clinical presentation consists of an acute or subacute flank pain with mild peritonism usually evoking appendicitis or cholecystitis. Recently, US and CT have proved to provide sufficiently typical, consistent and well-recognizable features to avoid unnecessary surgery. We report on six typical -five right sided and one left sided- cases investigated with CT and US. Two patients underwent surgical treatment, one because the usually spontaneous regression of the entity was ignored and the other because of extremely severe clinical symptoms. In the other four patients, conservative medical management was preferred and successful. Even though US may be efficient if performed by a well-trained echographist, CT appears to be the procedure of choice as it is operator independent and reliable for excluding mimicking surgical conditions or associated pathology.
 ...
PMID:[Pictorial essay. Infarction of the greater omentum: can US and CT findings help to avoid surgery?]. 1240 1

Torsion and/or infarction of the greater omentum are rare but well-recognized clinical situations which present as an acute abdomen. The etiology is unknown and speculative. In most cases, the pathology is right sided and clinical presentation consists of an acute or subacute flank pain with mild peritonism usually evoking appendicitis or cholecystitis. Nevertheless, knowledge concerning these two problems can help the surgeon in proper diagnosis and treatment. Since the first report on primary torsion by Eitel in 1899, a few hundred more have been reported and some collective reviews published to date. Recently, ultra sonography and computed tomography have proved to provide sufficiently typical, consistent, and well-recognizable features to avoid unnecessary surgery. In this study, we will present a case diagnosed as primary omental torsion based on computed tomography, which underwent successful conservative management.
 ...
PMID:Primary omental torsion in an old woman: imaging techniques can prevent unnecessary surgical interventions. 2173 34

This is a case report involving diagnostic errors that resulted in the death of a 15-year-old girl, and commentaries on the case from her parents and involved providers. Julia Berg presented with fatigue, fevers, sore throat and right sided flank pain. Based on a computed tomography (CT) scan that identified an abnormal-appearing gall bladder, and markedly elevated bilirubin and "liver function tests", she was hospitalized and ultimately underwent surgery for suspected cholecystitis and/or cholangitis. Julia died of unexplained post-operative complications. Her autopsy, and additional testing, suggested that the correct diagnosis was Epstein-Barr virus infection with acalculous cholecystitis. The correct diagnosis might have been considered had more attention been paid to her presenting symptoms, and a striking degree of lymphocytosis that was repeatedly demonstrated. The case illustrates how cognitive "biases" can contribute to harm from diagnostic error. The case has profoundly impacted the involved healthcare organization, and Julia's parents have become leaders in helping advance awareness and education about diagnostic error and its prevention.
 ...
PMID:Learning from tragedy: the Julia Berg story. 3042 78