Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0016199 (flank pain)
 2,189 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The incidence of testicular cancer in cryptorchidism is 30 to 50 times higher than in general population. We present a case of hydronephrosis caused by a seminoma in an abdominal cryptorchid testis. A 22 years old male presented abdominal and right flank pain, and haematuria. Despite the fact that he could not feel right testis since he was 7 years old, he had never looked for treatment. A huge mass was palpable in hypogastric, and IVP and CT Scan demonstrated functional exclusion of the right kidney, and a solid tumor localized at the right iliac fossa, near the bladder wall. The patient was submitted to laparotomy with resection of the mass, and the histopathologic study showed classic seminoma. Abdominal testes have higher incidence of malignancy than those in the inguinal position. The orchiopexy is recommended for abdominal testis after 2 years old to facilitate the investigation and identification of testicular cancer.
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PMID:Hydronephrosis secondary to a seminoma in abdominal cryptorchid testis. 1574 69

The role of un enhanced helical CT (UHCT) in the evaluation of acute flank pain suggestive of urinary tract calculi is increasingly appreciated in the last few years. Recent studies have identified the advantages of UHCT in recognizing alternative findings within or outside the urinary tract. These incidental diagnoses on UHCT alter a patient's management and demonstrate the pivotal role of UHCT in rapidly triaging these patients for appropriate management. Clinical impact of incidental diagnoses is maximal in identifying alternate emergent conditions mimicking reno-ureteric colic and in identifying malignancies at an early stage when they are potentially curable.
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PMID:Clinical impact of incidental diagnosis of disease on non-contrast-enhanced helical CT for acute ureteral colic. 1577 Dec 61

A 47-year-old female presenting with right flank pain and renal mass on ultrasonography was evaluated for renal malignancy. Based on the CT findings and blood aspiration on repeated fine needle aspiration biopsy the patient underwent radical nephrectomy. Histopathology revealed renal sinus hemangioma with normal kidney, perirenal fat and the hilar structures.
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PMID:Renal sinus hemangioma simulating renal mass: a diagnostic challenge. 1578 21

Simultaneous occurrence of renal cell carcinoma (RCC) and transitional cell carcinoma (TCC) in the same kidney is unusual. We report a 61-year-old man with ipsilateral synchronous renal adenocarcinoma and renal pelvic TCC. He was referred to our department for gross hematuria and right flank pain. CT and MRI studies revealed a 57 x 50 mm irregular and infiltrative upper right kidney mass with necrotic components. A right radical nephrectomy was done. Pathological diagnosis was a high grade tumor originating from just beneath the intact urothelium of renal pelvis and infiltrating through the parenchyma showing solid and occasional tubular growth patterns. A second tumor in close proximity to the first was reported as well differentiated RCC. This is a rare case of combined renal malignancies.
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PMID:Synchronous ipsilateral conventional renal cell and transitional cell carcinoma. 1578 24

Renal cell carcinoma arising from epithelial cells of the renal tubule is a highly aggressive and malignant tumor in all ages. Less than 2% of cases occur in childhood, relatively in older age group. Only a few pediatric series have been presented in the English literature. Tumor is presented with characteristic findings of flank pain, gross hematuria, and palpable mass. Although one half of the patients have metastasis at the time of diagnosis, most cases are currently being incidentally detected using improved imaging techniques. The overall prognosis in children appears to be similar to that in adults. Tumor stage and complete surgical resection have been reported as the most meaningful prognostic factors for the outcome. The incidence of metastatic disease is same as in adults. The effect of chemotherapy and immunotherapy, either preoperatively or postoperatively, is unclear. Cure is the most likely consequence in localized and completely resected tumors. Here, we present an 8-year-old boy with renal cell carcinoma demonstrating only hematuria without any pathological physical examination findings. The mass was described by abdominal ultrasonography and computed tomography in the left kidney. After the left nephroureterectomy, the patient was given no therapy.
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PMID:Renal cell carcinoma: case report and literature review. 1593

Primary renal lymphoma (PRL) is a rare lymphoma which usually presents with hematuria, flank pain, abdominal mass, and weight loss. PRL is more diagnosed in adults than children. We describe an asymptomatic child who presented with hypertension and was subsequently diagnosed with primary renal lymphoma. This case represents an atypical presentation for PRL.
Pediatr Blood Cancer 2007 Jun 15
PMID:Primary renal lymphoma presenting with hypertension. 1615 23

Lymphoplasmacytic sclerosing pancreatitis is a rare entity that has been described under many different names and constitutes a diagnostic challenge as it may simulate a neoplastic process. Herein, we report a case of a 61-year-old woman who presented to our institution complaining of left flank pain and was found to have normal levels of amylase and lipase. An abdominal magnetic resonance image showed thickening of the pancreatic tail and compression of the pancreatic duct. The radiographic differential included both chronic pancreatitis and a neoplastic process. She underwent an exploratory laparotomy, during which a pancreatectomy and splenectomy were performed. Grossly, the pancreas contained a yellowish white, firm homogeneous mass measuring 6.5 x 3.3 x 2.9 cm involving the entire pancreatic tail and hilum of the spleen. Histologically, pancreatic sections showed extensive fibrosis admixed with an inflammatory infiltrate. This infiltrate was composed mainly of lymphocytes with multiple germinal centers, as well as plasma cells and eosinophils that surrounded pancreatic ducts and extended into the peripancreatic adipose tissue. No malignancy was identified, and the process was diagnosed as lymphoplasmacytic sclerosing pancreatitis.
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PMID:Lymphoplasmacytic sclerosing pancreatitis. 1619 61

Dermatomyositis is an uncommon in flammatory myopathy with characteristic cutaneous manifestations which is frequently linked to several cancers. A 42-year-old man presented with left flank pain with typical symptoms of dermatomyositis. Computed tomography showed a solid mass in the pelvis of the left kidney and lymphadenopathy in the retroperitoneum. Since the general condition of the patient rapidly deteriorated because of marked muscle weakness of the respiratory muscles, the patient initially underwent medical treatment with prednisolone. After the improvement of respiratory function, the patient underwent radical nephroureterectomy and retroperitoneal lymphadenectomy. The pathological specimen showed moderately differentiated adenocarcinoma, stage pT3N2. After surgery, the patient showed a marked improvement of clinical symptoms related to dermatomyositis. Twenty-two months later, multiple organ metastases occurred and the patient died of cancer. We should point out the significance of surgical and medical treatment for these patients.
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PMID:Advanced renal pelvic carcinoma associated with dermatomyositis. 1632 85

Angiosarcoma is a rare malignant tumor occurring in less than 2% of soft tissue sarcomas. Angiosarcoma involving the kidney usually represents metastasis from skin or visceral primary lesions, while angiosarcoma primarily occurring in the kidney is a very rare neoplasm. In the English literature, from 1942 to the present, only 19 cases of primary kidney angiosarcoma have been reported. A case of primary renal angiosarcoma presenting as a large kidney mass and flank pain occurring after traumatism is reported. The present case represents further evidence of a rare malignancy.
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PMID:Primary renal angiosarcoma: a rare malignancy. A case report and review of the literature. 1681 82

Myelolipoma most commonly arises in the adrenal gland. Extra-adrenal myelolipomas are rare; to our knowledge, approximately 37 previous cases have been reported. We report a myelolipoma presenting as a localized mass in perirenal adipose tissue juxtaposed to the renal hilum in a 65-year-old Caucasian man who presented with back pain, weight loss, hematuria, and flank pain. The most likely diagnostic considerations were pyelonephritis or primary renal malignancy. However, histology revealed mainly mature adipose tissue along with multiple scattered islands of hematopoietic precursor cells. Representation of all the three hematopoietic cell lineages (granulocytic, erythroid, and megakaryocytic) was present. Perirenal masses such as morphologically identified myelolipomas are rarely, if ever, considered in differential diagnosis. The purpose of this report is to elicit consideration of extra-adrenal myelolipoma when formulating a differential diagnosis for perirenal and retroperitoneal tumors. Although primary and secondary malignant retroperitoneal tumors are much more common and aggressive neoplasms, establishing the correct diagnosis has important therapeutic and prognostic implications.
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PMID:Extra-adrenal myelolipoma in the renal hilum: a case report and review of the literature. 1683 Oct 34


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