Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0016053 (
fibromyalgia
)
4,687
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Sep
288
ACR
75
ankylosing spondylitis
66
substance P
60
c-fms
57
cytokine
48
Mol
40
IL-6
35
growth hormone
30
gut
27
C-reactive protein
26
opioid receptor
26
She
24
insulin
23
MRI
23
beta-endorphin
22
tumor necrosis factor
22
TNF
21
ANOVA
20
IL-10
20
brain-derived neurotrophic factor
20
rheumatoid factor
18
IL-8
17
HT3
16
ICD
16
SCL
16
GABA
16
collagen
16
REM
15
5-HT3 receptor
14
short form
14
calcitonin
14
Pol
14
interleukin-6
12
prolactin
11
HPA
11
CRP
11
HLA
10
enigma
10
ACTH
10
5-hydroxytryptamine
10
IL-1
10
interferon
10
IgA
9
insulin-like growth factor
9
IGF-1
9
CSF
9
serotonin transporter
9
catechol-O-methyltransferase
9
hemoglobin
9
lacrimal
8
mast cell
8
ATP
8
thyroid hormone
8
ESR
8
IL-2
8
FMR1
8
nerve growth factor
7
ANA
7
CRH
7
CBT
7
TNF-alpha
7
NMDA receptor
7
IL-4
7
leptin
7
parathyroid hormone
7
somatostatin
7
catalase
7
sit
7
NMR
7
sodium channel
6
olfactory
6
MOS
6
corticotropin-releasing factor
6
glucocorticoid receptor
6
cytochrome P450
6
5-HT2A
6
5-HTTLPR
6
CYP2D6
6
reserved
6
more...
Disease
fibromyalgia
4687
chronic pain
876
depression
792
rheumatoid arthritis
385
chronic fatigue syndrome
378
osteoarthritis
275
irritable bowel syndrome
262
arthritis
260
sleep disturbances
172
migraine
169
systemic lupus erythematosus
146
cognitive impairment
102
cold
90
sleep disorders
89
major depressive disorder
88
Best
88
psychological distress
78
anxiety disorders
76
diabetes
74
cancer
73
multiple sclerosis
72
rheumatism
71
ankylosing spondylitis
69
posttraumatic stress disorder
64
Myofascial pain syndrome
64
obesity
60
chronic disease
58
regional pain syndrome
55
hypertension
50
osteoporosis
49
neuropathy
49
lupus
49
asthma
46
Lyme disease
42
interstitial cystitis
41
mental illness
40
hypothyroidism
39
diabetic neuropathy
38
psoriatic arthritis
38
lupus
38
gout
36
postherpetic neuralgia
34
Alzheimer's disease
32
Parkinson's disease
31
arthropathy
31
emotional distress
30
vasculitis
30
epilepsy
30
autoimmune disease
28
peripheral neuropathy
27
confusion
27
schizophrenia
27
tension headache
27
musculoskeletal disease
26
HIV
24
hepatitis C
24
polymyalgia rheumatica
23
sexual abuse
23
stroke
23
endometriosis
23
PSS
22
inflammatory bowel disease
22
psoriasis
22
bipolar disorder
22
psychological stress
22
scleroderma
21
sleep apnea
21
Myofascial pain
21
Frey
21
TMJ
21
cardiovascular disease
19
affective disorder
19
tendinitis
19
Syndrome
18
bursitis
18
sexual dysfunction
18
tumor
17
connective tissue disease
17
addiction
17
panic disorder
17
more...
Symptom
pain
2963
fatigue
905
headache
331
myalgia
209
low back pain
173
back pain
92
insomnia
80
analgesia
75
generalized pain
75
arthralgia
57
discomfort
46
neck pain
46
weakness
43
dizziness
40
pelvic pain
35
discomfort
34
sleepiness
34
nausea
33
facial pain
30
seizures
29
acute pain
29
body pain
28
paresthesia
27
abdominal pain
26
diarrhea
24
chest pain
23
spasm
23
alexithymia
22
overweight
22
exhaustion
20
shoulder pain
20
tinnitus
19
chronic back pain
19
constipation
19
tremor
18
cancer pain
18
ataxia
17
vomiting
17
muscle stiffness
15
neuralgia
14
erythema
13
numbness
13
anesthesia
12
stigma
12
distraction
11
dyspnea
11
vertigo
11
Ill
10
bladder pain
10
asthenia
9
spasticity
9
Depressive symptoms
9
dystonia
9
syncope
9
knee pain
8
dental pain
8
Joint hypermobility
8
joint stiffness
8
sciatica
8
dry eye
8
limb pain
8
acute stress
8
Tenderness
8
angina
8
orofacial pain
8
bone pain
7
memory loss
6
tingling
6
heartburn
5
mental fatigue
5
sore throat
5
agitation
5
flushing
5
Neuropathic pain
5
Musculoskeletal symptoms
5
blurred vision
4
hypersomnia
4
Wind
4
growing pains
4
stomach pain
4
more...
Drug
Pregabalin
50
Domperidone
35
Duloxetine
32
CFS
29
Reserpine
10
Ranitidine
10
CSF
9
IL-2
8
Dermatol
6
Asthma
6
Gabapentin
5
ascorbate
5
ROC
5
Growth hormone
4
caffeine
4
Growth hormone
4
Spectrum
3
ADM
3
BH4
3
Award
3
Mirtazapine
3
TMS
3
CPM
3
Monit
3
Flexeril
2
Nephron
2
DPA
2
PPA
2
Check
2
Tetrax
2
lactose
2
Fosamax
2
pyridoxal phosphate
2
IFN-gamma
2
Android
2
Spectrum
2
ROS
2
ENT
2
TRM
2
Gel
2
Portal
2
Ritanserin
1
Rituximab
1
Duloxetine hydrochloride
1
Prozac
1
Propidium
1
Elm
1
Salbutamol
1
Zoloft
1
Posture
1
ACT
1
Nabilone
1
ABC
1
EE2
1
Doxycycline
1
9-THC
1
Hypaque
1
DHT
1
lysine
1
Modafinil
1
Effexor
1
TES
1
CAM
1
Luteinizing
1
Tryptophane
1
PCP
1
Denosumab
1
Triad
1
Tramadol hydrochloride
1
GEO
1
niacin
1
Ketalar
1
Bifidobacterium
1
Nimesulide
1
Platelet Activating Factor
1
Tramal
1
Desvenlafaxine succinate
1
Moxifloxacin
1
THF
1
Tiaprofenic acid
1
more...
Enzyme
ERK
63
monoamine oxidase
11
creatine kinase
9
catalase
7
peroxidase
6
superoxide dismutase
6
alkaline phosphatase
5
mitogen-activated protein kinase
5
alanine aminotransferase
4
tryptophan hydroxylase
4
MCS
4
protein kinase C
4
glutathione peroxidase
4
focal adhesion kinase
3
aspartate aminotransferase
3
AMP-activated protein kinase
3
CPM
3
prolyl endopeptidase
2
transglutaminase
2
CFI
2
elastase
2
adenosine deaminase
2
lactate dehydrogenase
2
trypsin
2
transaldolase
2
AMPK
2
citrate synthase
2
protein kinase
2
thyroid peroxidase
2
AMPK
2
CYP3A4
2
adenosine deaminase
2
reverse transcriptase
2
NAT
2
caspase-1
2
alpha-amylase
2
phosphodiesterase
2
ACE
2
SST
1
phospholipase C
1
ornithine decarboxylase
1
renin
1
ADE2
1
kyotorphin synthetase
1
peroxiredoxin
1
carbonic anhydrase
1
acetylcholinesterase
1
kallikrein
1
PCP
1
calcineurin
1
GTP cyclohydrolase I
1
P-glycoprotein
1
pyruvate dehydrogenase
1
CPT
1
STR
1
neutrophil elastase
1
transketolase
1
methylenetetrahydrofolate reductase
1
dipeptidyl peptidase IV
1
FAST
1
5'-nucleotidase
1
CD10
1
glutathione reductase
1
collagenase
1
PGM
1
aldehyde dehydrogenase
1
phosphatidylinositol 3-kinase
1
lysozyme
1
proteasome
1
beta-glucuronidase
1
ACS
1
tryptase
1
CCS
1
CPT
1
thromboplastin
1
DAT
1
AST
1
paraoxonase
1
ATPase
1
ceruloplasmin
1
more...
Compound
Clin
765
Dec
321
5-HT
54
calcium
51
water
47
oxygen
46
noradrenaline
39
glutamate
35
DNA
34
tryptophan
33
tryptophan
32
tryptophan
32
tryptophan
32
sodium
29
vitamin D
24
nitric oxide
21
TNF
21
DSM
17
Amitriptyline
16
phosphate
16
GABA
16
GABA
16
coenzyme Q10
14
glucose
13
ACTH
12
gamma-aminobutyric acid
11
Vitamin D
10
methionine
10
Melatonin
10
Reserpine
10
adenosylmethionine
9
selenium
8
creatinine
8
potassium
8
ATP
8
TSH
8
ANA
7
5-hydroxytryptophan
7
ANA
7
NMDA
7
Coenzyme Q10
7
HAQ
6
Naltrexone
6
Tropisetron
6
phosphorus
6
salt
6
Cortisol
6
iron
6
sulfate
6
CES
6
glutamine
5
isoleucine
5
Thyroid
5
proline
5
Substance P
5
acetate
5
CO2
5
Ketamine
5
Optimal
5
hydroxyindoleacetic acid
5
isoleucine
5
zinc
5
Malondialdehyde
5
Ile
5
valine
4
cysteine
4
Venlafaxine
4
EDS
4
His
4
Estrogen
4
Phe
4
serine
4
hydrogen
4
arginine
4
Estrogen
4
phosphocreatine
4
ubiquinone
4
N-acetylaspartate
4
leucine
4
caffeine
4
more...