Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0016053 (fibromyalgia)
4,687 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 288
ACR 75
ankylosing spondylitis 66
substance P 60
c-fms 57
cytokine 48
Mol 40
IL-6 35
growth hormone 30
gut 27
C-reactive protein 26
opioid receptor 26
She 24
insulin 23
MRI 23
beta-endorphin 22
tumor necrosis factor 22
TNF 21
ANOVA 20
IL-10 20
brain-derived neurotrophic factor 20
rheumatoid factor 18
IL-8 17
HT3 16
ICD 16
SCL 16
GABA 16
collagen 16
REM 15
5-HT3 receptor 14
short form 14
calcitonin 14
Pol 14
interleukin-6 12
prolactin 11
HPA 11
CRP 11
HLA 10
enigma 10
ACTH 10
5-hydroxytryptamine 10
IL-1 10
interferon 10
IgA 9
insulin-like growth factor 9
IGF-1 9
CSF 9
serotonin transporter 9
catechol-O-methyltransferase 9
hemoglobin 9
lacrimal 8
mast cell 8
ATP 8
thyroid hormone 8
ESR 8
IL-2 8
FMR1 8
nerve growth factor 7
ANA 7
CRH 7
CBT 7
TNF-alpha 7
NMDA receptor 7
IL-4 7
leptin 7
parathyroid hormone 7
somatostatin 7
catalase 7
sit 7
NMR 7
sodium channel 6
olfactory 6
MOS 6
corticotropin-releasing factor 6
glucocorticoid receptor 6
cytochrome P450 6
5-HT2A 6
5-HTTLPR 6
CYP2D6 6
reserved 6
more...
Disease
fibromyalgia 4687
chronic pain 876
depression 792
rheumatoid arthritis 385
chronic fatigue syndrome 378
osteoarthritis 275
irritable bowel syndrome 262
arthritis 260
sleep disturbances 172
migraine 169
systemic lupus erythematosus 146
cognitive impairment 102
cold 90
sleep disorders 89
major depressive disorder 88
Best 88
psychological distress 78
anxiety disorders 76
diabetes 74
cancer 73
multiple sclerosis 72
rheumatism 71
ankylosing spondylitis 69
posttraumatic stress disorder 64
Myofascial pain syndrome 64
obesity 60
chronic disease 58
regional pain syndrome 55
hypertension 50
osteoporosis 49
neuropathy 49
lupus 49
asthma 46
Lyme disease 42
interstitial cystitis 41
mental illness 40
hypothyroidism 39
diabetic neuropathy 38
psoriatic arthritis 38
lupus 38
gout 36
postherpetic neuralgia 34
Alzheimer's disease 32
Parkinson's disease 31
arthropathy 31
emotional distress 30
vasculitis 30
epilepsy 30
autoimmune disease 28
peripheral neuropathy 27
confusion 27
schizophrenia 27
tension headache 27
musculoskeletal disease 26
HIV 24
hepatitis C 24
polymyalgia rheumatica 23
sexual abuse 23
stroke 23
endometriosis 23
PSS 22
inflammatory bowel disease 22
psoriasis 22
bipolar disorder 22
psychological stress 22
scleroderma 21
sleep apnea 21
Myofascial pain 21
Frey 21
TMJ 21
cardiovascular disease 19
affective disorder 19
tendinitis 19
Syndrome 18
bursitis 18
sexual dysfunction 18
tumor 17
connective tissue disease 17
addiction 17
panic disorder 17
more...
Symptom
pain 2963
fatigue 905
headache 331
myalgia 209
low back pain 173
back pain 92
insomnia 80
analgesia 75
generalized pain 75
arthralgia 57
discomfort 46
neck pain 46
weakness 43
dizziness 40
pelvic pain 35
discomfort 34
sleepiness 34
nausea 33
facial pain 30
seizures 29
acute pain 29
body pain 28
paresthesia 27
abdominal pain 26
diarrhea 24
chest pain 23
spasm 23
alexithymia 22
overweight 22
exhaustion 20
shoulder pain 20
tinnitus 19
chronic back pain 19
constipation 19
tremor 18
cancer pain 18
ataxia 17
vomiting 17
muscle stiffness 15
neuralgia 14
erythema 13
numbness 13
anesthesia 12
stigma 12
distraction 11
dyspnea 11
vertigo 11
Ill 10
bladder pain 10
asthenia 9
spasticity 9
Depressive symptoms 9
dystonia 9
syncope 9
knee pain 8
dental pain 8
Joint hypermobility 8
joint stiffness 8
sciatica 8
dry eye 8
limb pain 8
acute stress 8
Tenderness 8
angina 8
orofacial pain 8
bone pain 7
memory loss 6
tingling 6
heartburn 5
mental fatigue 5
sore throat 5
agitation 5
flushing 5
Neuropathic pain 5
Musculoskeletal symptoms 5
blurred vision 4
hypersomnia 4
Wind 4
growing pains 4
stomach pain 4
more...
Drug
Pregabalin 50
Domperidone 35
Duloxetine 32
CFS 29
Reserpine 10
Ranitidine 10
CSF 9
IL-2 8
Dermatol 6
Asthma 6
Gabapentin 5
ascorbate 5
ROC 5
Growth hormone 4
caffeine 4
Growth hormone 4
Spectrum 3
ADM 3
BH4 3
Award 3
Mirtazapine 3
TMS 3
CPM 3
Monit 3
Flexeril 2
Nephron 2
DPA 2
PPA 2
Check 2
Tetrax 2
lactose 2
Fosamax 2
pyridoxal phosphate 2
IFN-gamma 2
Android 2
Spectrum 2
ROS 2
ENT 2
TRM 2
Gel 2
Portal 2
Ritanserin 1
Rituximab 1
Duloxetine hydrochloride 1
Prozac 1
Propidium 1
Elm 1
Salbutamol 1
Zoloft 1
Posture 1
ACT 1
Nabilone 1
ABC 1
EE2 1
Doxycycline 1
9-THC 1
Hypaque 1
DHT 1
lysine 1
Modafinil 1
Effexor 1
TES 1
CAM 1
Luteinizing 1
Tryptophane 1
PCP 1
Denosumab 1
Triad 1
Tramadol hydrochloride 1
GEO 1
niacin 1
Ketalar 1
Bifidobacterium 1
Nimesulide 1
Platelet Activating Factor 1
Tramal 1
Desvenlafaxine succinate 1
Moxifloxacin 1
THF 1
Tiaprofenic acid 1
more...
Enzyme
ERK 63
monoamine oxidase 11
creatine kinase 9
catalase 7
peroxidase 6
superoxide dismutase 6
alkaline phosphatase 5
mitogen-activated protein kinase 5
alanine aminotransferase 4
tryptophan hydroxylase 4
MCS 4
protein kinase C 4
glutathione peroxidase 4
focal adhesion kinase 3
aspartate aminotransferase 3
AMP-activated protein kinase 3
CPM 3
prolyl endopeptidase 2
transglutaminase 2
CFI 2
elastase 2
adenosine deaminase 2
lactate dehydrogenase 2
trypsin 2
transaldolase 2
AMPK 2
citrate synthase 2
protein kinase 2
thyroid peroxidase 2
AMPK 2
CYP3A4 2
adenosine deaminase 2
reverse transcriptase 2
NAT 2
caspase-1 2
alpha-amylase 2
phosphodiesterase 2
ACE 2
SST 1
phospholipase C 1
ornithine decarboxylase 1
renin 1
ADE2 1
kyotorphin synthetase 1
peroxiredoxin 1
carbonic anhydrase 1
acetylcholinesterase 1
kallikrein 1
PCP 1
calcineurin 1
GTP cyclohydrolase I 1
P-glycoprotein 1
pyruvate dehydrogenase 1
CPT 1
STR 1
neutrophil elastase 1
transketolase 1
methylenetetrahydrofolate reductase 1
dipeptidyl peptidase IV 1
FAST 1
5'-nucleotidase 1
CD10 1
glutathione reductase 1
collagenase 1
PGM 1
aldehyde dehydrogenase 1
phosphatidylinositol 3-kinase 1
lysozyme 1
proteasome 1
beta-glucuronidase 1
ACS 1
tryptase 1
CCS 1
CPT 1
thromboplastin 1
DAT 1
AST 1
paraoxonase 1
ATPase 1
ceruloplasmin 1
more...
Compound
Clin 765
Dec 321
5-HT 54
calcium 51
water 47
oxygen 46
noradrenaline 39
glutamate 35
DNA 34
tryptophan 33
tryptophan 32
tryptophan 32
tryptophan 32
sodium 29
vitamin D 24
nitric oxide 21
TNF 21
DSM 17
Amitriptyline 16
phosphate 16
GABA 16
GABA 16
coenzyme Q10 14
glucose 13
ACTH 12
gamma-aminobutyric acid 11
Vitamin D 10
methionine 10
Melatonin 10
Reserpine 10
adenosylmethionine 9
selenium 8
creatinine 8
potassium 8
ATP 8
TSH 8
ANA 7
5-hydroxytryptophan 7
ANA 7
NMDA 7
Coenzyme Q10 7
HAQ 6
Naltrexone 6
Tropisetron 6
phosphorus 6
salt 6
Cortisol 6
iron 6
sulfate 6
CES 6
glutamine 5
isoleucine 5
Thyroid 5
proline 5
Substance P 5
acetate 5
CO2 5
Ketamine 5
Optimal 5
hydroxyindoleacetic acid 5
isoleucine 5
zinc 5
Malondialdehyde 5
Ile 5
valine 4
cysteine 4
Venlafaxine 4
EDS 4
His 4
Estrogen 4
Phe 4
serine 4
hydrogen 4
arginine 4
Estrogen 4
phosphocreatine 4
ubiquinone 4
N-acetylaspartate 4
leucine 4
caffeine 4
more...