Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0016053 (fibromyalgia)
 4,687 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
immunoglobulin lambda variable 3-25 12.7
NAT15 11.7
ZNF77 10.4
toll interacting protein 9.9
NOV1 9.7
B2GPI 8.9
CPCI 8.6
MYT1L 8.6
RRAS2 8.4
GPR171 8.4
pp52 8.2
opioid growth factor receptor 8.0
NRXN3 7.9
transcription factor A, mitochondrial 7.8
ARHGDIB 7.7
DPM1 7.7
PRKG1 7.7
Dopamine D3 receptor 7.7
NDUFB11 7.7
ETK 7.6
HTR3B 7.6
ACR 7.6
CSNB1 7.6
c-fms 7.4
RTN1 7.3
somatomedin C) 7.3
human leucocyte antigen D 7.3
SCN11A 7.2
Apolipoprotein C-III 7.1
Mu opioid receptor 7.0
prepronociceptin 6.9
TNFRSF13B 6.9
ASIC3 6.9
HTR3A 6.8
GAT2 6.8
IL1RAPL1 6.7
Serotonin receptor 6.6
TC21 6.4
proSAAS 6.4
ankylosing spondylitis 6.3
myoadenylate deaminase 6.2
HLA-DR beta 6.2
glucocorticoid-induced leucine zipper 6.1
SIGIRR 6.1
lysophosphatidic acid receptor 6.1
LSP1 6.0
CCL23 6.0
MPD 6.0
Hpr 6.0
OPRM1 6.0
FSS 6.0
PNI 5.9
NR3C2 5.8
PRKCA 5.8
calgranulin C 5.8
GABAB2 5.8
SCL 5.8
stiff person syndrome 5.7
CD85j 5.7
MOS 5.7
TMD 5.7
TRIM21 5.6
BL2 5.5
fragile X mental retardation protein 5.5
Catechol-O-methyltransferase 5.4
Microtubule-associated protein 5.4
HT3 5.4
SCN9A 5.4
profilin 1 5.4
Nav1.7 5.4
5-HT3 receptor 5.4
ADRA2A 5.4
NBL 5.4
RDC 5.3
DQ1 5.3
helicase II 5.3
IL-1RA 5.3
LBP 5.3
CaMKK 5.3
ribosomal protein S6 kinase 1 5.3
prolyl endopeptidase 5.3
FMR1 5.3
GCH1 5.3
Alpha-1 antitrypsin 5.2
PCS 5.2
protein kinase C epsilon 5.2
transaldolase 5.2
somatomedin C 5.2
MCS 5.2
COXIV 5.1
CXCL6 5.1
catechol-O-methyltransferase 5.1
IL-1 receptor accessory protein 5.1
ILT2 5.1
M2BP 5.1
MERRF 5.1
TSD 5.0
SMD 5.0
LAL 5.0
TNS 5.0
proteinase-activated receptor-2 5.0
Malate dehydrogenase 4.9
SIP 4.9
ES2 4.9
MSF 4.9
GAT-3 4.9
GRIN2B 4.9
CPM 4.9
CD132 4.9
butyrobetaine 4.9
apolipoprotein D 4.9
Eotaxin 4.8
NNT 4.8
beta-3 4.8
L19 4.8
EKC 4.8
IL-31 4.8
GBP 4.8
enigma 4.7
FMRP 4.7
HAD 4.7
MAP1LC3B 4.7
HPA 4.7
ALF 4.7
MDD 4.7
TTR 4.7
orphan G protein-coupled receptor 4.7
Glutamic acid decarboxylase 4.6
EGR 4.6
gamma-amino butyric acid 4.6
TRPV2 4.6
GAT1 4.6
peroxisome proliferator activated receptor gamma 4.6
rheumatoid factor 4.6
FKBP51 4.6
Agrin 4.6
rBAT 4.6
TPH1 4.5
short form 4.5
NRSF 4.5
DM2 4.5
NPS 4.5
LPA1 4.5
macrophage-derived chemokine 4.5
CBT 4.5
AWS 4.5
OIF 4.5
FIM 4.5
CD151 4.4
5-HTTLPR 4.4
HDAC4 4.4
CRF2 4.4
NAT 4.4
MPI 4.4
FLU 4.4
CRF1 4.3
PAX7 4.3
CBG 4.3
P2X3 4.3
TRPM2 4.3
more...
Disease
Primary fibrositis 12.7
autoimmune rheumatologic disease 12.7
Primary Fibromyalgia 12.7
fibromyalgia 12.7
Secondary fibrositis 12.7
Myofascial pain syndrome 12.5
Undifferentiated Somatoform Disorder 11.7
Chronic hypertrophic rhinitis 11.7
Rubella arthritis 11.7
Primary fibromyalgia syndrome 11.0
Myofascial pain 10.4
Chronic blepharitis 10.4
Enteropathic arthritis 10.4
Hypermobility syndrome 10.3
Barre-Lieou syndrome 9.9
SLE arthritis 9.9
Pain Disorder 9.9
chronic fatigue syndrome 9.8
Moderate depression 9.6
Hypervigilance 9.5
Corneal deposits 9.4
neuromyasthenia 9.2
humeroscapular periarthritis 9.1
Eosinophilia myalgia syndrome 9.0
Atypical depression 8.9
Nutcracker esophagus 8.8
FXTAS 8.8
Chronic paroxysmal hemicrania 8.7
renal scleroderma 8.6
dermographia 8.6
regional pain syndrome 8.4
Piriformis syndrome 8.3
chronic pain 8.3
proctalgia fugax 8.1
chemical hypersensitivity 8.1
tension headache 8.0
Dercum's disease 8.0
sick building syndrome 7.9
emotionally unstable personality 7.9
irritable bowel syndrome 7.8
Multiple chemical sensitivity 7.8
Delayed sleep phase syndrome 7.8
Vulvar vestibulitis 7.8
interstitial cystitis 7.8
Atlantoaxial instability 7.7
sleep disturbances 7.7
Baastrup 7.7
urethral syndrome 7.7
combat fatigue 7.6
somatization disorder 7.6
Occipital neuralgia 7.6
musculoskeletal disease 7.5
psychogenic pain 7.4
Ross syndrome 7.4
rheumatism 7.4
crystal arthropathy 7.3
Tietze 7.3
postherpetic neuralgia 7.2
rotator cuff syndrome 7.2
Jaccoud 7.2
Fibrillary glomerulonephritis 7.1
gluten sensitivity 7.1
galactocele 7.1
Lichen planopilaris 7.0
polymyalgia rheumatica 7.0
muscle contraction headache 7.0
sicca syndrome 7.0
phantom limb pain 6.9
psychological disease 6.9
Postural orthostatic tachycardia syndrome 6.9
Generalized epilepsy 6.8
pseudopelade 6.8
epicondylitis 6.8
Chronic migraine 6.8
dysautonomia 6.8
reactive depression 6.7
enthesitis 6.7
Somatization 6.7
JHS 6.6
psychogenic disorders 6.6
Gulf War Syndrome 6.6
Quervain 6.6
heritable connective tissue disorder 6.6
palindromic rheumatism 6.6
Carnitine deficiency 6.5
Steinbrocker 6.5
Suicide risk 6.5
psychological disturbance 6.5
bursitis 6.5
organic disease 6.4
sleep disorders 6.4
Other variants 6.4
Beard 6.4
Temporomandibular Disorders 6.3
osteopoikilosis 6.3
tendinitis 6.3
neurodermatitis 6.2
lumbar spondylosis 6.2
hypochondriasis 6.2
TMJ 6.2
psychosomatic disorders 6.2
FSS 6.2
diabetic neuropathy 6.2
ankylosing spondylitis 6.2
apophysitis 6.1
compulsive personality 6.1
JMS 6.1
dactylitis 6.1
Lyme arthritis 6.1
Mixed cryoglobulinemia 6.1
migraine 6.1
Sjogren's syndrome 6.1
alcoholic neuropathy 6.1
anxiety neurosis 6.1
reflex sympathetic dystrophy 6.0
anxiety depression 6.0
Female sexual dysfunction 6.0
psychological distress 6.0
emotional trauma 6.0
Collagenous colitis 5.9
Complex regional pain syndrome 5.9
psoriatic arthritis 5.9
metabolic syndrome X 5.9
postpolio syndrome 5.9
neurotic depression 5.9
Horton 5.9
restless legs syndrome 5.8
muscle swelling 5.8
dental abscess 5.8
thoracic outlet syndrome 5.8
frozen shoulder 5.8
Frey 5.8
spondyloarthropathy 5.8
tennis elbow 5.8
osteoarthritis 5.7
Spondyloarthritis 5.7
TMD 5.7
RSI 5.7
hysteria 5.7
Rust 5.6
rheumatoid arthritis 5.6
Vasovagal syncope 5.6
Scheuermann's disease 5.6
lichen simplex chronicus 5.6
de Quervain's disease 5.6
compulsive personality disorder 5.6
SFS 5.6
gout 5.6
Ehlers-Danlos syndrome 5.5
disabling disease 5.5
spondylitis 5.5
Tumor-induced osteomalacia 5.5
valvulitis 5.5
keratoconjunctivitis sicca 5.5
vaginosis 5.4
guttate psoriasis 5.4
menopausal syndrome 5.4
premenstrual dysphoric disorder 5.4
Burning mouth syndrome 5.4
Sleep disturbance 5.4
more...
Symptom
Other chronic pain 12.7
generalized pain 11.3
Chest wall tenderness 11.1
Diffuse pain 10.9
Craniofacial Pain 10.4
Vertigo/dizziness 9.9
Pain worsened 9.6
Acute back pain 9.6
Multiple symptoms 9.5
body pain 9.5
Neurogenic pain 8.8
cervical spine dysfunction 8.8
Joint hypermobility 8.8
loss of feeling 8.6
Chronic tension-type headache 8.6
Somatic pain 8.3
Musculoskeletal symptoms 8.3
rib pain 8.3
vaginal discomfort 8.3
growing pains 8.1
Localized pain 8.0
Muscle tenderness 8.0
glossodynia 7.9
myalgia 7.8
abdominal rigidity 7.7
Mechanical pain 7.7
Pain and tenderness 7.6
change in stool 7.5
bladder pain 7.4
chronic back pain 7.4
physical exhaustion 7.4
vestibulitis 7.3
Vulvodynia 7.3
Tenderness 7.2
Referred pain 7.0
fatigue 6.9
low back pain 6.9
polymyalgia 6.9
Exercise intolerance 6.9
Visceral pain 6.9
Fatigability 6.8
Subjective tinnitus 6.6
leg cramps 6.5
Inflammatory pain 6.5
alexithymia 6.4
feeling tired 6.4
facial pain 6.4
muscle stiffness 6.4
physical symptom 6.4
limb pain 6.3
neck pain 6.3
pain 6.3
Poor sleep 6.2
rectal pain 6.2
Chronic pelvic pain 6.1
hand pain 6.0
disturbed balance 5.9
pelvic pain 5.9
mental fatigue 5.9
orofacial pain 5.8
neuralgia 5.8
stomach pain 5.8
arthralgia 5.8
mastalgia 5.7
back pain 5.7
joint stiffness 5.7
insomnia 5.7
acute pain 5.6
shoulder pain 5.6
breakthrough pain 5.6
Muscle soreness 5.5
dental pain 5.5
elbow pain 5.5
arm pain 5.3
forgetfulness 5.3
headache 5.3
cancer pain 5.3
frequent urination 5.3
swollen joints 5.3
hyperacusis 5.2
paresthesia 5.2
eye pain 5.2
sciatica 5.1
tingling 5.0
Depressive symptoms 4.9
ACHE 4.9
dysesthesia 4.8
dizziness 4.8
aphonia 4.8
lightheadedness 4.7
postnasal drip 4.7
hypersomnia 4.7
acute low back pain 4.6
urinary frequency 4.6
Neuropathic pain 4.6
asthenia 4.5
atypical chest pain 4.4
spasm 4.4
dry eye 4.4
tinnitus 4.3
knee pain 4.3
analgesia 4.2
sleepiness 4.2
numbness 4.1
bloating 4.0
heartburn 4.0
bone pain 3.9
loss of balance 3.9
muscle cramps 3.9
otalgia 3.8
syncopal episodes 3.8
chronic cough 3.7
blurred vision 3.7
hyperesthesia 3.7
abdominal cramps 3.7
discomfort 3.7
Hudson 3.7
torticollis 3.7
constipation 3.7
sore throat 3.6
breath holding 3.6
acute stress 3.6
memory loss 3.5
hot flushes 3.5
hypertonia 3.4
vertigo 3.4
Wind 3.4
discomfort 3.4
leg pain 3.3
exhaustion 3.3
nausea 3.3
spasticity 3.2
chest pain 3.2
groin pain 3.2
photophobia 3.1
despair 3.1
dysuria 3.1
enuresis 3.0
distraction 3.0
livedo 3.0
epigastric pain 3.0
abdominal discomfort 3.0
weakness 2.9
hip pain 2.9
ataxia 2.9
dystonia 2.9
snoring 2.8
Stiffness 2.8
erythema 2.7
blepharospasm 2.7
tremor 2.7
syncope 2.7
hot flashes 2.7
muscle rigidity 2.7
Postoperative pain 2.6
tense 2.6
stigma 2.6
Ill 2.6
rhinorrhea 2.6
overweight 2.5
more...
Drug
Flexeril 10.4
Pregabalin 9.6
Duloxetine 9.4
Celestone 8.7
Desvenlafaxine succinate 8.6
Tetrax 8.5
Domperidone 8.5
CFS 8.3
Duloxetine hydrochloride 7.8
Tryptophane 7.7
Fosamax 7.6
Effexor 7.4
Platelet Activating Factor 7.1
Tramadol hydrochloride 7.1
Alosetron 7.1
Nabilone 7.0
Tiaprofenic acid 6.8
Elm 6.7
Ketalar 6.7
Zoloft 6.7
Ketalar 6.2
Reserpine 6.1
Tramal 6.1
Mirtazapine 6.0
Tapentadol 5.9
Ranitidine 5.4
Gabapentin 5.2
Ritanserin 5.2
Agomelatine 5.2
TRM 5.2
CPM 5.1
Pramipexole 5.1
Pramipexole 5.0
Prozac 4.8
OIF 4.8
Propidium 4.7
PPA 4.5
Nimesulide 4.5
SPP 4.2
Zonisamide 4.2
Modafinil 4.1
Android 4.1
Olive oil 4.1
Moxifloxacin 3.9
BH4 3.7
Denosumab 3.6
TES 3.6
Emodin 3.6
Award 3.5
Triad 3.5
DPA 3.4
Growth hormone 3.2
Growth hormone 3.2
TMS 3.1
BoNT/A 3.0
TAK 2.8
Check 2.8
Salbutamol 2.7
Luteinizing 2.7
ADM 2.7
Doxycycline 2.6
Hypaque 2.6
pyridoxal phosphate 2.4
NBT 2.4
ROC 2.1
GEO 2.1
9-THC 2.0
Spectrum 1.7
Portal 1.7
ACT 1.7
DHT 1.6
DHT 1.6
Fragment 1.5
Spectrum 1.4
Rituximab 1.2
CSF 1.0
IL-2 0.9
PCP 0.9
niacin 0.8
ENT 0.7
Asthma 0.7
ascorbate 0.6
Albumin 0.5
caffeine 0.3
Posture 0.3
CAM 0.2
Bifidobacterium 0.2
Gel -0.1
EE2 -0.2
THF -0.3
lactose -0.3
ABC -0.4
nitroglycerin -0.4
Nephron -0.4
ROS -0.5
Monit -0.8
IFN-gamma -1.1
Dermatol -2.7
lysine -3.1
Cardiovasc -4.9
Enzyme
kyotorphin synthetase 10.4
MCS 5.1
transaldolase 5.1
CPM 4.9
ADE2 4.9
NAT 4.4
CFI 4.1
prolyl endopeptidase 4.1
tryptophan hydroxylase 3.9
CCS 3.5
GTP cyclohydrolase I 3.4
monoacylglycerol lipase 3.3
FAST 3.2
SST 3.2
Rex 2.9
monoamine oxidase 2.8
CPS 2.4
TPP 2.4
transketolase 2.4
PGM 2.3
TPP 2.2
DAT 2.2
ERK 2.2
thyroid peroxidase 2.1
dipeptidyl peptidase IV 2.0
paraoxonase 2.0
AOR 1.9
botulinum neurotoxin 1.8
paraoxonase 1.7
creatine kinase 1.7
methylenetetrahydrofolate reductase 1.7
lactase 1.7
methylenetetrahydrofolate reductase 1.7
citrate synthase 1.6
transglutaminase 1.5
adenosine deaminase 1.4
adenosine deaminase 1.4
alpha-amylase 1.4
peroxiredoxin 1.4
tryptase 1.3
caspase-1 1.1
AMPK 1.1
5'-nucleotidase 1.1
CYP3A4 1.1
CPT 1.1
STR 1.1
UDP-glucuronosyltransferase 1.0
CPT 1.0
PCP 0.9
neutrophil elastase 0.7
AMP-activated protein kinase 0.6
elastase 0.6
CPT 0.6
MIP 0.5
ceruloplasmin 0.4
pyruvate dehydrogenase 0.3
glutathione peroxidase 0.3
kallikrein 0.2
AST 0.2
AMPK 0.1
ornithine decarboxylase 0.1
aldehyde dehydrogenase 0.1
alanine aminotransferase 0.0
lipoprotein lipase -0.0
aspartate aminotransferase -0.1
carbonic anhydrase -0.1
beta-glucuronidase -0.2
catalase -0.2
xanthine oxidase -0.3
ACE -0.4
phosphodiesterase -0.5
glutathione reductase -0.5
alkaline phosphatase -0.5
CD10 -0.5
superoxide dismutase -0.5
peroxidase -0.7
phosphatidylinositol 3-kinase -0.7
tissue plasminogen activator -0.7
protein kinase C -0.9
cholinesterase -0.9
thromboplastin -1.0
P-glycoprotein -1.0
lactate dehydrogenase -1.1
focal adhesion kinase -1.1
reverse transcriptase -1.2
calcineurin -1.3
collagenase -1.4
phospholipase C -1.4
lipase -1.5
mitogen-activated protein kinase -1.5
trypsin -1.6
lysozyme -1.7
glutathione S-transferase -1.7
acetylcholinesterase -2.1
proteasome -2.1
renin -2.4
protein kinase -2.6
ATPase -3.3
ACS -3.5
Compound
Ibuproxam 10.7
Flexeril 9.9
Myrtenol 8.7
Felbinac 8.6
Tropisetron 8.1
I acid 8.0
Cyclobenzaprine 7.8
Dothiepin 7.6
5-methylhexanoic acid 7.5
Amitriptyline 7.4
Methylsulfonylmethane 7.2
25-Hydroxyvitamin D 7.0
Dimenhydrinate 6.9
HAQ 6.7
3-Hydroxykynurenine 6.4
Mirtazapine 6.3
PTO 6.2
Tizanidine 6.2
R 2010 6.2
SHB 6.1
Venlafaxine 5.9
Cuprizone 5.8
C 10 5.6
DDM 5.6
C 10 5.6
Esculetin 5.5
Quetiapine 5.4
DQ1 5.3
Naltrexone 5.3
Coenzyme Q10 5.3
coenzyme Q10 5.3
Tramadol 5.3
Ziprasidone 5.3
Reserpine 5.1
Silver, 5.0
CES 4.9
Sertraline 4.8
Trazodone 4.8
TPB 4.8
Fisetin 4.7
Oxycodone 4.7
DMM 4.7
5-HTP 4.6
5-HTP 4.6
DDM 4.6
Bupropion 4.6
Dextromethorphan 4.4
Betamethasone 4.3
PPA 4.3
Ribose 4.2
aceturate 4.2
Gold, 4.1
Gold, 4.1
Gold, 4.1
NOP 4.1
TES 4.0
phenylacetaldehyde 4.0
Morin 4.0
Corticotropin 4.0
Moxifloxacin 3.9
MAOA 3.9
5-hydroxytryptophan 3.9
phenylacetaldehyde 3.9
Ketamine 3.9
Citalopram 3.9
Cannabidiol 3.8
phenylacetaldehyde 3.8
DPN 3.8
MEP 3.8
Malondialdehyde 3.7
ECP 3.7
ECP 3.7
ECP 3.7
Tetrahydrocannabinol 3.6
Triiodothyronine 3.6
MEP 3.6
5-HT 3.5
ANA 3.5
ANA 3.5
Memantine 3.5
Etanercept 3.5
CCS 3.4
CoQ 3.4
Substance P 3.4
Melatonin 3.4
Vitamin D 3.4
PPA 3.3
gamma-hydroxybutyric acid 3.3
Phosphatidylserine 3.3
Spironolactone 3.2
1,4-butanediol 3.2
Ketanserin 3.2
DEP 3.2
Lidocaine 3.1
hydroxyindoleacetic acid 3.1
PAG 3.1
N-acetylaspartate 3.1
AEA 3.0
noradrenaline 3.0
AAT 3.0
EDS 3.0
Olanzapine 2.9
Cortisol 2.9
NBQX 2.9
adenosylmethionine 2.9
SAD 2.8
Minocycline 2.8
DEP 2.8
PSP 2.8
ITP 2.7
Salbutamol 2.7
neopterin 2.7
PID 2.7
Xenon 2.7
Diclofenac 2.7
PID 2.7
Creatine 2.7
APS 2.7
Doxycycline 2.7
tryptophan 2.6
tryptophan 2.6
L-T3 2.6
tryptophan 2.6
Rose Bengal 2.6
vitamin D 2.5
HCI 2.5
DPG 2.5
dipropyl 2.5
phosphocreatine 2.4
keratan sulfate 2.4
tryptophan 2.4
1,8-cineole 2.4
Statin 2.4
AEA 2.4
TPP 2.3
NBT 2.3
gamma-aminobutyric acid 2.3
Uric acid 2.2
Chlorpromazine 2.2
Interleukin-2 2.2
DAT 2.2
ubiquinone 2.2
PDT 2.2
Amide 2.1
myristic acid 2.1
DSM 2.1
ACTH 2.1
Methamphetamine 2.0
Morphine 2.0
ubiquinol 2.0
Ibuprofen 2.0
TPP 2.0
DPG 1.9
Choline 1.9
Chloroquine 1.9
Chloroquine 1.9
L-carnitine 1.8
PGD2 1.8
myristic acid 1.8
TSH 1.8
more...