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Query: UMLS:C0016053 (fibromyalgia)
 4,687 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Evidence of the benefit of exercise for patients with musculoskeletal problems was examined by analysing meta-analyses and systematic reviews. The literature search was confined to studies where pain and/or function was used as the outcome measure. Twenty-three meta-analyses/systematic reviews were covered, and the methodical quality was assessed. Nine out of twelve meta-analyses showed that exercise had a positive effect on groups groups diagnosed with intermittent claudication, fibromyalgia, incontinence, low back pain, and stroke, whereas one meta-analysis (exercise to prevent falls in the elderly) showed no effect. Of the systematic reviews, six out of 12 showed a positive effect and five were inconclusive, owing to the lack of clinical trials. We conclude that much more research in the field of exercise and physiotherapy is needed.
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PMID:[Evidence-based grounds of physical therapy. Focus on training/exercise therapy of musculoskeletal problems]. 1181 Jul 92

The authors report a case of a 52-year old female previously followed at the Outpatient Rheumatology Clinic with the diagnosis of Fibromyalgia (FM). Approximately 2 years after this diagnosis, she presents with a 2nd degree burn in a hand, as a result of thermal hypoesthesia. The patient described hipostesia of the distal upper and lower limbs, incontinence of the anal sphincter and chronic diarrhoea with progressive worsening. The electromiography showed sensory-motor axonal polyneuropathy, chronic, moderate to severe. The muscle and nerve biopsy showed deposition of amyloid substance. The search for TTR Met 30 was positive, confirming the diagnosis of familial amyloidotic polyneuropathy. This is the first reported case of familial amyloidotic polyneuropathy as part of the differential diagnosis of fibromyalgia.
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PMID:[An unusual case of generalized pain: paramyloidosis simulating fibromyalgia]. 1972 56