Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0015695 (fatty liver)
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Human Gene/Protein
C9orf52 11.2
kelch repeat and BTB (POZ) domain containing 2 11.2
ARNT2 protein 11.2
GPCR12 11.2
Aryl hydrocarbon receptor nuclear translocator 2 11.2
Glycerol-3-phosphate acyltransferase, mitochondrial 11.2
isoamyl acetate-hydrolyzing esterase 1 homolog 11.2
ACACA protein 11.2
PCSK7 protein 11.2
BCO2 protein 11.2
Yip1 domain family, member 6 11.2
RCE1 protein 11.2
transmembrane protein 199 11.2
FAM166B 11.2
MOGAT3 10.6
transmembrane 6 superfamily member 2 10.2
ZNF70 10.2
LDPL 10.2
Transmembrane 6 superfamily member 2 10.2
HSD13 10.2
mitochondrial glycerol 3-phosphate acyltransferase 10.2
JAZF zinc finger 1 10.2
ADP-ribosylation factor-like 1 10.2
OR10J5 10.2
glycerol-3-phosphate acyltransferase, mitochondrial 9.9
MOGAT1 9.8
TM6SF2 9.7
PNPLA3 9.6
zinc finger MYND domain-containing protein 9.6
Acetyl-CoA synthetase 2 9.6
CWF19L1 9.6
ADP-ribosylation factor related protein 1 9.6
TDRD10 9.6
lysophospholipase-like 1 9.6
KIAA0188 9.6
GOLIATH 9.6
ubiquitin-like modifier activating enzyme 3 9.6
chemokine receptor-like 1 9.6
TM6SF2 protein 9.6
FABP1 protein 9.6
STK25 protein 9.6
hypoxia-inducible protein 2 9.4
FSP27 9.3
MBOAT7 9.3
Neuregulin 4 9.3
LPPR4 9.2
CIDEC protein 9.2
KBTBD2 9.2
AD031 9.2
MIG12 9.2
WDR27 9.2
enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase 9.2
glutathione S-transferase alpha 1 9.2
HMGCS2 protein 9.2
Monoacylglycerol O-acyltransferase 2 9.2
PPP1R3G 9.2
HSD17B13 9.2
SID1 transmembrane family member 2 9.2
SEIPIN 9.0
sterol regulatory element-binding protein-1c 9.0
ERLIN1 9.0
TMC4 9.0
neuregulin 4 9.0
fetuin B 9.0
FATP5 8.9
carboxylesterase 3 8.9
MTTP 8.9
cornea-derived transcript 6 8.8
CCDC3 8.8
PS-PLA1 8.8
CRLS1 8.8
TMEM159 8.8
USP10 protein 8.8
promethin 8.8
acyl-CoA thioesterase 1 8.8
TRPC4AP 8.8
SAMM50 8.8
Zinc finger protein 267 8.8
human homolog of mouse double minute 2 8.8
acetyl-CoA carboxylase 1 8.8
more...
Disease
Carnitine palmitoyltransferase 1 deficiency 11.2
fatty liver 11.2
Shock symptoms 10.2
Allergic diarrhea 10.2
Acute fatty liver 9.8
Acute fatty liver of pregnancy 9.7
Nonalcoholic fatty liver 9.6
Phlegmonous enteritis 9.6
Other liver diseases 9.6
Cage layer fatigue 9.6
Acquired generalized lipodystrophy 9.6
alcoholic fatty liver 9.2
Leucocytozoonosis 9.2
Cobalamin C disease 9.2
Lipoatrophic diabetes 9.2
Coproporphyrinuria 9.2
Advanced chronic liver disease 9.2
NFLD 8.8
Hepatic calcification 8.8
generalized lipodystrophy 8.7
Cryptogenic cirrhosis 8.7
yellow atrophy 8.7
Chronic liver disease and cirrhosis 8.7
choline deficiency 8.6
Mitochondrial neurogastrointestinal encephalopathy 8.6
Mitochondrial trifunctional protein deficiency 8.6
Alcoholic liver disease 8.5
hypobetalipoproteinemia 8.4
FHBL2 8.4
Acyl-CoA dehydrogenase deficiency 8.4
Acute toxic hepatitis 8.4
alcoholic hepatitis 8.3
chylomicron retention disease 8.3
Armanni-Ebstein lesion 8.2
Android obesity 8.0
Jordan's anomaly 8.0
Zieve's syndrome 7.9
hypolipoproteinemia 7.9
Familial partial lipodystrophy 7.8
Fatty acid oxidation defects 7.8
acute alcoholic hepatitis 7.7
Brown bowel syndrome 7.7
HELLP syndrome 7.6
CTLN2 7.6
Hepatic congestion 7.6
Acute and chronic pancreatitis 7.5
Hepatobiliary disease 7.5
Septic abortion 7.5
cholesterol ester storage disease 7.4
lipodystrophy 7.4
Aromatase deficiency 7.4
Spinocerebellar degeneration 7.4
Hepatic osteodystrophy 7.4
chronic liver disease 7.3
ethanolism 7.3
metabolic syndrome 7.2
pancreatic islet hyperplasia 7.2
bladder polyp 7.2
fructosuria 7.2
lipidosis 7.2
liver fibrosis 7.1
Acute viral hepatitis 7.1
Essential mixed cryoglobulinemia 7.1
NALD 7.1
overnutrition 7.0
liver disease 6.9
PFIC3 6.9
Severe hypothyroidism 6.9
Coronary arteritis 6.8
acetonemia 6.8
dyslipidemia 6.8
lipid disorder 6.8
CGL2 6.8
liver scarring 6.8
pediatric liver cancer 6.8
Cerebellar degeneration 6.8
Renal cortical necrosis 6.7
Adult growth hormone deficiency 6.7
cirrhosis 6.7
ketosis 6.7
more...
Symptom
swollen penis 7.8
Appetite suppression 7.8
hyperemesis gravidarum 7.2
intestinal pain 6.6
hepatomegaly 6.1
breast hyperplasia 6.0
epigastric distress 5.6
intestinal angina 5.1
Skin symptoms 5.0
ketonuria 5.0
Cushingoid 5.0
Cushingoid 4.9
corpulence 4.9
overweight 4.7
BHS 4.4
hypoproteinemia 4.3
hyperemesis 3.9
polydipsia 3.7
right upper quadrant pain 3.7
Decreased activity 3.7
prostration 3.6
polyuria 3.4
Spots 3.3
splenomegaly 2.9
No adverse effect 2.8
emaciation 2.7
starvation 2.6
abdominal fullness 2.5
epigastric pain 2.4
hepatosplenomegaly 2.4
clubbing 2.4
vomiting 2.2
Stiffness 2.2
cachexia 2.2
abdominal cramps 2.1
POA 2.1
bloating 2.0
breath holding 2.0
lethargy 2.0
abdominal discomfort 2.0
nausea 1.9
anorexia 1.9
abdominal pain 1.8
chronic constipation 1.8
asthenia 1.8
Ill 1.5
intestinal bleeding 1.5
menopausal symptoms 1.5
hypotonia 1.4
cerebellar ataxia 1.3
muscle cramps 1.3
oliguria 1.3
hypersomnia 1.1
diarrhea 1.1
nausea and vomiting 1.1
Postoperative pain 1.1
productive cough 1.0
abnormal gait 1.0
constipation 1.0
decreased appetite 1.0
night sweats 0.9
memory loss 0.9
hot flushes 0.9
fatigue 0.9
Wind 0.8
tonic-clonic seizure 0.8
bitter taste 0.7
HSA 0.6
acute stress 0.6
acute abdomen 0.6
exertional dyspnea 0.4
arthralgia 0.3
hunger 0.3
chronic cough 0.2
fever of unknown origin 0.1
weakness 0.1
heartburn 0.1
myalgia 0.1
respiratory distress -0.1
hypothermia -0.1
more...
Drug
Lofrin 10.2
Schisandra fruit 9.8
Sergliflozin 8.8
Metreleptin 8.4
Colestimide 8.2
Citrus unshiu peel 8.1
Axokine 8.0
Cassia seed 8.0
Psyllium husk 7.6
Creosote 7.5
Malotilate 7.4
Carnauba wax 7.3
Muraglitazar 7.1
Platelet concentrate 7.1
Darapladib 6.8
Ezetimibe 6.4
Exenatide 6.3
Fructose 6.2
Liraglutide 6.1
Gadobenate dimeglumine 6.0
Gd-BOPTA 5.9
Red ginseng 5.9
Glucose-6-Phosphate 5.9
Lipitor 5.8
Bezafibrate 5.6
1-Deoxynojirimycin 5.5
Coconut oil 5.5
Colesevelam 5.4
Humalog 5.4
Lipitor 5.4
Lipitor 5.4
Rosiglitazone 5.2
Beraprost sodium 5.1
Rimonabant 5.1
Olmesartan 5.0
Marimastat 5.0
Tritiated water 4.9
Ciprofibrate 4.9
Kenyan 4.8
Pegvisomant 4.8
Humulin 4.8
CDX 4.7
Olmesartan medoxomil 4.7
Ethanol 4.6
Valproic Acid 4.6
AMK 4.6
Orlistat 4.6
Malonaldehyde 4.5
Myricetin 4.5
Sevelamer 4.4
CDX 4.3
Sesamol 4.3
Glucagon 4.2
Proglumide 4.2
Idebenone 4.2
Dimethylformamide 4.2
Etodolac 4.2
Levovist 4.1
Febuxostat 4.0
CCL 4.0
FLM 3.9
Corn oil 3.9
Soybean oil 3.9
NLF 3.9
vitamin E 3.9
Sonazoid 3.8
3-Methyladenine 3.8
2-Methoxyestradiol 3.8
niacin 3.7
L-Asparaginase 3.7
Vitamin E 3.6
Tibolone 3.6
Artemether 3.6
SNL 3.6
Clofibrate 3.6
Carbenoxolone 3.6
Casodex 3.6
Lipidex 3.6
Isoniazid 3.6
TAK 3.5
more...
Enzyme
carnitine O-octanoyltransferase 7.8
ketohexokinase 7.6
mannosyl-oligosaccharide glucosidase 7.6
retinol saturase 7.5
MGAT 7.5
phosphatidylethanolamine N-methyltransferase 7.3
acetyl-CoA carboxylase 7.2
fatty-acid synthase 7.1
diacylglycerol acyltransferase 7.0
citrate cleavage enzyme 6.8
trihydroxycoprostanoyl-CoA oxidase 6.7
acyl-CoA oxidase 6.7
betaine-homocysteine methyltransferase 6.6
alkylglycerol monooxygenase 6.6
1-acylglycerol-3-phosphate O-acyltransferase 6.5
monoacylglycerol acyltransferase 6.5
alanine aminotransferase 6.5
glycine dehydrogenase 6.5
glycine dehydrogenase 6.5
phosphatidate phosphatase 6.4
CYP7A1 6.4
electron transfer flavoprotein dehydrogenase 6.4
AST 6.4
phytanoyl-CoA hydroxylase 6.4
NSY 6.3
AMP-activated protein kinase 6.2
fructokinase 6.2
AMPK 6.2
AMP-activated kinase 6.2
nicotinamide N-methyltransferase 6.2
phosphoethanolamine cytidylyltransferase 6.2
aspartate aminotransferase 6.1
acyl-CoA reductase 6.1
CPT 6.0
triokinase 6.0
3-hydroxyacyl-CoA dehydrogenase 6.0
fatty acid elongase 6.0
acyl-CoA thioesterase 5.9
sterol carrier protein 5.9
aminocarboxymuconate-semialdehyde decarboxylase 5.9
glycine N-methyltransferase 5.8
acetoacetyl-CoA synthetase 5.8
dihydroxyacetone phosphate acyltransferase 5.8
EC 1.1.1.39 5.8
glycine dehydrogenase 5.8
long-chain acyl-coenzyme A dehydrogenase 5.8
butyryl-CoA dehydrogenase 5.7
lysine-ketoglutarate reductase 5.7
acyl-CoA dehydrogenase 5.7
glycerophosphate acyltransferase 5.7
HMG-CoA synthase 5.6
acylglycerol kinase 5.5
inosine triphosphatase 5.5
acyl-CoA dehydrogenase 5.4
3-hydroxyacyl-CoA dehydrogenase 5.4
gamma-glutamyl transpeptidase 5.4
hormone-sensitive lipase 5.4
pantetheinase 5.4
sarcosine dehydrogenase 5.4
glutamic dehydrogenase 5.4
site-1 protease 5.4
CPT 5.3
AMPK 5.2
acyl-CoA synthetase 5.2
nicotinamide phosphoribosyltransferase 5.2
CPT 5.2
nardilysin 5.2
D-dopachrome tautomerase 5.1
pyruvate carboxylase 5.0
glycerol kinase 5.0
arachidonate 5-lipoxygenase 4.9
threonine aldolase 4.9
acyl-CoA synthetase 4.9
LPL 4.9
carbamoylphosphate synthetase 4.9
lipoprotein lipase 4.9
sphingomyelin synthase 4.9
glycine amidinotransferase 4.8
lecithin:retinol acyltransferase 4.8
retinyl ester hydrolase 4.8
more...
Compound
Dienestrol diacetate 11.2
Calcion 10.2
2-acetyl-1,3-cyclopentanedione 9.2
2,2',4,4',5,5'-Hexachlorobiphenyl 8.8
Mepanipyrim 8.7
Ouabagenin 8.6
Wuweizisu C 8.6
Turinabol 8.6
3,4,3',4'-Tetrachlorobiphenyl 8.6
Eriocitrin 8.4
Ginkgolide C 8.2
C20H30O3 8.2
atropic acid 8.0
9(S)-HODE 8.0
Saponarin 8.0
Scopolin 8.0
Thyronine 7.7
Sennoside A 7.6
Oil Red O 7.6
DJP 7.6
Coumarin 7 7.6
Coumarin 7 7.5
cholesta-3,5-dien-7-one 7.5
Oil Red O 7.4
cholesta-4,6-dien-3-one 7.4
Acetylshikonin 7.3
Norephedrine 7.3
Ginkgolide C 7.3
Ammonium pyrrolidine dithiocarbamate 7.2
Raspberry ketone 7.1
Rhaponticin 7.1
Ethionine 7.0
Ruscogenin 7.0
cholestane-3beta,5alpha,6beta-triol 7.0
Adrenic acid 7.0
Coniferaldehyde 6.8
6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde 6.8
Rubratoxin B 6.8
2,4,6-trihydroxybenzaldehyde 6.8
Oil Red 6.7
allyl formate 6.7
Stachydrine 6.6
Glucoraphanin 6.6
Oxyresveratrol 6.5
Erucic acid 6.5
4-APP 6.5
Octyl gallate 6.4
HFr 6.3
Ginkgolide A 6.3
Pioglitazone 6.3
ORO 6.2
Gentiopicroside 6.2
Pinitol 6.2
Conjugated linoleic acid 6.2
Stearoyl-CoA 6.2
Swertiamarin 6.2
Anserine 6.2
Catalpol 6.1
Fructose 6.1
Glycerol-3-phosphate 6.1
Patchouli alcohol 6.1
GC-1 6.0
Polydatin 6.0
Vinyl chloride 6.0
alpha-Amanitin 5.9
Glycerate 5.9
Deoxypodophyllotoxin 5.9
Geniposide 5.9
Tributyltin chloride 5.9
Stachydrine 5.9
Thiazolidinedione 5.9
Acyl-CoA 5.9
Novex 5.8
Laminariaceae 5.8
FFA 5.8
Isoliquiritigenin 5.8
3,5-T2 5.8
Dihydromyricetin 5.7
palmitic acid 5.7
Osthole 5.7
more...