Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0015695 (fatty liver)
13,941 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
insulin 3742
Sep 810
Mol 728
alanine aminotransferase 580
gut 514
leptin 438
aspartate aminotransferase 429
endoplasmic reticulum 413
adiponectin 400
peroxisome proliferator-activated receptor 379
fatty acid synthase 354
tumor necrosis factor 303
TNF 280
cytokine 264
HDL 260
AMP-activated protein kinase 249
AST 224
AMPK 204
collagen 199
sterol regulatory element-binding protein 183
PPAR 180
IL-6 176
glucagon 176
ATP 175
acetyl-CoA carboxylase 172
epididymal 163
SREBP-1c 159
superoxide dismutase 155
peroxisome proliferator-activated receptor gamma 152
GSH 144
albumin 128
alkaline phosphatase 126
microsomal 126
nuclear receptor 120
lipopolysaccharide 116
stearoyl-CoA desaturase 114
C-reactive protein 112
mTOR 110
interleukin-6 109
adipokine 109
hemoglobin 107
TLR4 106
PNPLA3 104
SREBP-1 103
FAS 101
CD36 101
apolipoprotein B 97
catalase 93
MRI 89
JNK 89
cytochrome P450 86
lipoprotein lipase 85
farnesoid X receptor 85
microsomal triglyceride transfer protein 84
caspase-3 83
AKT 83
insulin receptor 81
NAD 80
interferon 79
peroxisome proliferator-activated receptor alpha 79
carnitine palmitoyltransferase 78
IRS-1 75
glutathione peroxidase 75
PGC 73
ROS 71
perilipin 70
CYP2E1 68
She 68
Nrf2 67
uncoupling protein 1 67
Leptin 66
ACC 66
Fibroblast growth factor 21 65
ferritin 64
SCD1 63
NMR 63
SOD 61
SIRT1 61
AMP 61
reductase 61
more...
Disease
fatty liver 13941
obesity 3794
cirrhosis 1889
diabetes 1858
liver disease 1642
metabolic syndrome 1592
type 2 diabetes 1277
Nonalcoholic fatty liver 1177
hepatocellular carcinoma 1130
alcoholic fatty liver 931
dyslipidemia 696
cancer 638
chronic liver disease 618
hypertension 550
hyperlipidemia 545
cardiovascular disease 514
liver fibrosis 512
hepatitis 446
atherosclerosis 432
glucose intolerance 419
hepatitis C 419
hyperglycemia 418
chronic hepatitis 373
hyperinsulinemia 298
viral hepatitis 268
tumor 265
hepatitis B 237
liver cancer 227
alcoholic hepatitis 193
hypercholesterolemia 191
cholestasis 190
liver cancer 188
lipodystrophy 160
GSH 144
hypoglycemia 134
alcohol abuse 118
ischemia 117
preeclampsia 116
metabolic disorder 115
malnutrition 109
gallstones 106
FAS 104
HIV 99
alcoholic cirrhosis 94
HELLP syndrome 94
carcinogenesis 93
ketosis 90
alcoholism 89
virus infection 86
Hepatocellular carcinoma 85
cold 76
polycystic ovary syndrome 74
portal hypertension 74
Alcoholic liver disease 74
carcinoma 73
stroke 73
tumorigenesis 71
primary biliary cirrhosis 71
chronic active hepatitis 68
iron overload 68
coronary heart disease 67
pancreatitis 66
generalized lipodystrophy 63
abdominal obesity 63
hyperphagia 63
overnutrition 62
hemochromatosis 59
immunodeficiency 58
obstructive sleep apnea 55
depression 55
hepatic encephalopathy 54
sepsis 54
inflammatory bowel disease 54
hyperuricemia 53
cardiomyopathy 53
coronary artery disease 53
renal disease 51
heart failure 50
osteoporosis 50
breast cancer 50
more...
Symptom
overweight 290
hepatomegaly 176
starvation 68
vomiting 65
diarrhea 54
abdominal pain 49
fatigue 41
nausea 39
hyperemesis gravidarum 35
splenomegaly 32
anesthesia 28
pain 25
seizures 25
anorexia 22
weakness 18
polyuria 14
Ill 14
polydipsia 13
cachexia 11
lethargy 10
hepatosplenomegaly 10
hypoproteinemia 10
collapse 9
constipation 9
nausea and vomiting 9
ketonuria 8
epigastric pain 8
respiratory distress 8
hypotonia 7
hypothermia 7
headache 7
discomfort 6
discomfort 6
ataxia 6
dyspnea 6
exhaustion 5
arthralgia 4
right upper quadrant pain 4
asthenia 4
erythema 4
thinning 4
cerebellar ataxia 4
angina 4
sleepiness 4
acute stress 3
emaciation 3
bloating 3
abdominal discomfort 3
memory loss 3
Cushingoid 3
hunger 3
hypercapnia 3
Cushingoid 3
myalgia 3
stigma 3
Decreased activity 3
hyperemesis 2
HSA 2
Stiffness 2
syncope 2
tremor 2
menopausal symptoms 2
Spots 2
acidity 2
oliguria 2
acute abdomen 2
paresis 2
prostration 2
exertional dyspnea 2
analgesia 2
Wind 2
chronic constipation 2
clubbing 2
corpulence 1
intestinal bleeding 1
bitter taste 1
knee pain 1
abdominal fullness 1
night sweats 1
Skin symptoms 1
more...
Drug
vitamin E 112
Ethanol 107
ROS 71
Fructose 60
lysine 54
NADH 54
Kenyan 42
Glucagon 31
Cardiovasc 29
niacin 22
ascorbate 22
ROC 20
Bifidobacterium 20
Monit 19
Vitamin E 18
Ezetimibe 17
Dermatol 17
Portal 16
caffeine 16
EPA 14
Rosiglitazone 13
Liraglutide 13
CAM 13
ALA 13
Exenatide 11
Albumin 11
Growth hormone 11
Leaf 10
Growth hormone 10
Glutathione 10
CCL 9
PCB 8
citric acid 8
Glycyrrhiza 7
Vitamin A 7
CSF 7
IFN-gamma 7
EE2 6
Fluorescein 6
IL-2 6
MAP 6
lactose 6
Bezafibrate 6
Estrogens 5
Sorafenib 5
Alanine 5
TAK 5
Rimonabant 5
DMI 5
Isoniazid 5
ADM 5
Parkin 4
Activin 4
Propofol 4
Tacrolimus 4
Histamine 4
Orlistat 4
Creosote 4
Ginseng 4
p75 4
Parkin 4
Glycerol 3
Red ginseng 3
linolenate 3
Olmesartan 3
Heme 3
AZT 3
CDX 3
CDX 3
Retinoic acid 3
AZT 3
Bortezomib 3
Clofibrate 3
Indomethacin 3
Oxaliplatin 3
Metreleptin 3
Rutin 3
Gd-BOPTA 3
Simvastatin 3
Myricetin 3
more...
Enzyme
alanine aminotransferase 1030
aspartate aminotransferase 640
AMP-activated protein kinase 434
AST 224
mitogen-activated protein kinase 211
superoxide dismutase 207
AMPK 206
AMPK 204
protein kinase 203
acetyl-CoA carboxylase 182
gamma-glutamyl transpeptidase 171
CPT 131
alkaline phosphatase 128
catalase 110
lipoprotein lipase 90
glutathione peroxidase 81
lipase 74
ERK 71
luciferase 67
CPT 56
CPT 56
caspase-3 54
phosphoenolpyruvate carboxykinase 52
diacylglycerol acyltransferase 50
phosphoenolpyruvate carboxykinase 43
phosphoenolpyruvate carboxykinase 43
acyl-CoA oxidase 43
lactate dehydrogenase 43
focal adhesion kinase 39
reverse transcriptase 39
hormone-sensitive lipase 39
protein kinase C 38
glucose-6-phosphatase 37
CYP7A1 37
ATPase 35
acyl-CoA dehydrogenase 33
complex I 32
NADPH oxidase 30
NADPH oxidase 30
cholinesterase 30
alcohol dehydrogenase 29
glucokinase 28
aldehyde dehydrogenase 27
proteasome 27
peroxidase 27
glutamate dehydrogenase 26
glutamate dehydrogenase 26
glutamate dehydrogenase 26
acetylcholinesterase 26
phosphatidylinositol 3-kinase 25
renin 25
glutathione S-transferase 24
glucose-6-phosphate dehydrogenase 23
creatine kinase 22
ACS 21
aldehyde dehydrogenase 21
pyruvate carboxylase 21
acyl-CoA synthetase 21
pyruvate kinase 19
3-hydroxyacyl-CoA dehydrogenase 19
aldehyde dehydrogenase 19
glutathione reductase 19
GSK 19
phospholipase A2 19
CYP3A4 19
aldehyde dehydrogenase 19
aldehyde dehydrogenase 19
LPL 18
collagenase 18
MEK 18
caspase-1 17
ceruloplasmin 17
cholesterol acyltransferase 16
phosphatidylethanolamine N-methyltransferase 16
citrate synthase 16
ACE 15
AMP-activated kinase 15
acyl-CoA dehydrogenase 15
NO synthase 15
IKK 14
more...
Compound
glucose 2380
Clin 972
Dec 834
ethanol 698
oxygen 479
water 431
DNA 402
methionine 369
Insulin 314
TNF 280
iron 181
palmitic acid 177
ATP 175
CoA 172
palmitic acid 158
GSH 150
GSH 150
phosphate 149
glycerol 135
calcium 126
sodium 121
Oil Red O 110
Oil Red O 102
NAD 101
alanine 99
NAD 80
acetate 79
betaine 76
galactose 73
AMP 68
homocysteine 68
vitamin D 64
nitric oxide 63
adenosylmethionine 63
Fructose 61
Cholesterol 60
lysine 59
nitrogen 59
serine 59
aldehyde 59
tyrosine 58
cysteine 57
nicotinamide 56
CPT 56
urea 56
CPT 56
arginine 55
NADH 54
glutamate 53
CCl4 53
salt 52
FFA 52
MDA 47
acetaldehyde 47
creatinine 46
silver 46
zinc 44
cAMP 43
His 43
leucine 43
copper 42
PMA 42
hydrogen 40
retinol 40
tryptophan 38
tryptophan 38
acetyl-CoA 38
Metformin 37
Metformin 37
Choline 35
GPT 35
threonine 35
tryptophan 35
tryptophan 35
ammonia 35
CO2 34
Resveratrol 32
Hematoxylin 31
Glucagon 31
NADPH 30
more...