Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0015695 (fatty liver)
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Human Gene/Protein
GPCR12 11.2
isoamyl acetate-hydrolyzing esterase 1 homolog 11.2
ACACA protein 11.2
PCSK7 protein 11.2
C9orf52 11.2
RCE1 protein 11.2
BCO2 protein 11.2
transmembrane protein 199 11.2
Aryl hydrocarbon receptor nuclear translocator 2 11.2
Yip1 domain family, member 6 11.2
ARNT2 protein 11.2
Glycerol-3-phosphate acyltransferase, mitochondrial 11.2
kelch repeat and BTB (POZ) domain containing 2 11.2
FAM166B 11.2
MOGAT3 10.6
transmembrane 6 superfamily member 2 10.2
ZNF70 10.2
JAZF zinc finger 1 10.2
LDPL 10.2
OR10J5 10.2
ADP-ribosylation factor-like 1 10.2
HSD13 10.2
mitochondrial glycerol 3-phosphate acyltransferase 10.2
Transmembrane 6 superfamily member 2 10.2
glycerol-3-phosphate acyltransferase, mitochondrial 9.9
MOGAT1 9.8
TM6SF2 9.7
PNPLA3 9.6
GOLIATH 9.6
CWF19L1 9.6
KIAA0188 9.6
Acetyl-CoA synthetase 2 9.6
ADP-ribosylation factor related protein 1 9.6
TDRD10 9.6
FABP1 protein 9.6
STK25 protein 9.6
TM6SF2 protein 9.6
lysophospholipase-like 1 9.6
ubiquitin-like modifier activating enzyme 3 9.6
chemokine receptor-like 1 9.6
more...
Disease
Carnitine palmitoyltransferase 1 deficiency 11.2
fatty liver 11.2
Shock symptoms 10.2
Allergic diarrhea 10.2
Acute fatty liver 9.8
Acute fatty liver of pregnancy 9.7
Nonalcoholic fatty liver 9.6
Acquired generalized lipodystrophy 9.6
Cage layer fatigue 9.6
Other liver diseases 9.6
Phlegmonous enteritis 9.6
alcoholic fatty liver 9.2
Cobalamin C disease 9.2
Coproporphyrinuria 9.2
Advanced chronic liver disease 9.2
Leucocytozoonosis 9.2
Lipoatrophic diabetes 9.2
NFLD 8.8
Hepatic calcification 8.8
generalized lipodystrophy 8.7
Cryptogenic cirrhosis 8.7
yellow atrophy 8.7
Chronic liver disease and cirrhosis 8.7
choline deficiency 8.6
Mitochondrial trifunctional protein deficiency 8.6
Mitochondrial neurogastrointestinal encephalopathy 8.6
Alcoholic liver disease 8.5
hypobetalipoproteinemia 8.4
FHBL2 8.4
Acute toxic hepatitis 8.4
Acyl-CoA dehydrogenase deficiency 8.4
alcoholic hepatitis 8.3
chylomicron retention disease 8.3
Armanni-Ebstein lesion 8.2
Jordan's anomaly 8.0
Android obesity 8.0
Zieve's syndrome 7.9
hypolipoproteinemia 7.9
Familial partial lipodystrophy 7.8
Fatty acid oxidation defects 7.8
more...
Symptom
swollen penis 7.8
Appetite suppression 7.8
hyperemesis gravidarum 7.2
intestinal pain 6.6
hepatomegaly 6.1
breast hyperplasia 6.0
epigastric distress 5.6
intestinal angina 5.1
Skin symptoms 5.0
ketonuria 5.0
Cushingoid 5.0
Cushingoid 4.9
corpulence 4.9
overweight 4.7
BHS 4.4
hypoproteinemia 4.3
hyperemesis 3.9
polydipsia 3.7
right upper quadrant pain 3.7
Decreased activity 3.7
prostration 3.6
polyuria 3.4
Spots 3.3
splenomegaly 2.9
No adverse effect 2.8
emaciation 2.7
starvation 2.6
abdominal fullness 2.5
epigastric pain 2.4
hepatosplenomegaly 2.4
clubbing 2.4
vomiting 2.2
Stiffness 2.2
cachexia 2.2
abdominal cramps 2.1
POA 2.1
bloating 2.0
breath holding 2.0
lethargy 2.0
abdominal discomfort 2.0
more...
Drug
Lofrin 10.2
Schisandra fruit 9.8
Sergliflozin 8.8
Metreleptin 8.4
Colestimide 8.2
Citrus unshiu peel 8.1
Axokine 8.0
Cassia seed 8.0
Psyllium husk 7.6
Creosote 7.5
Malotilate 7.4
Carnauba wax 7.3
Platelet concentrate 7.1
Muraglitazar 7.1
Darapladib 6.8
Ezetimibe 6.4
Exenatide 6.3
Fructose 6.2
Liraglutide 6.1
Gadobenate dimeglumine 6.0
Gd-BOPTA 5.9
Red ginseng 5.9
Glucose-6-Phosphate 5.9
Lipitor 5.8
Bezafibrate 5.6
1-Deoxynojirimycin 5.5
Coconut oil 5.5
Colesevelam 5.4
Humalog 5.4
Lipitor 5.4
Lipitor 5.4
Rosiglitazone 5.2
Beraprost sodium 5.1
Rimonabant 5.1
Olmesartan 5.0
Marimastat 5.0
Tritiated water 4.9
Ciprofibrate 4.9
Kenyan 4.8
Pegvisomant 4.8
more...
Enzyme
carnitine O-octanoyltransferase 7.8
ketohexokinase 7.6
mannosyl-oligosaccharide glucosidase 7.6
MGAT 7.5
retinol saturase 7.5
phosphatidylethanolamine N-methyltransferase 7.3
acetyl-CoA carboxylase 7.2
fatty-acid synthase 7.1
diacylglycerol acyltransferase 7.0
citrate cleavage enzyme 6.8
trihydroxycoprostanoyl-CoA oxidase 6.7
acyl-CoA oxidase 6.7
betaine-homocysteine methyltransferase 6.6
alkylglycerol monooxygenase 6.6
1-acylglycerol-3-phosphate O-acyltransferase 6.5
monoacylglycerol acyltransferase 6.5
alanine aminotransferase 6.5
glycine dehydrogenase 6.5
glycine dehydrogenase 6.5
phosphatidate phosphatase 6.4
CYP7A1 6.4
electron transfer flavoprotein dehydrogenase 6.4
AST 6.4
phytanoyl-CoA hydroxylase 6.4
NSY 6.3
AMP-activated protein kinase 6.2
fructokinase 6.2
AMPK 6.2
AMP-activated kinase 6.2
nicotinamide N-methyltransferase 6.2
phosphoethanolamine cytidylyltransferase 6.2
aspartate aminotransferase 6.1
acyl-CoA reductase 6.1
CPT 6.0
triokinase 6.0
3-hydroxyacyl-CoA dehydrogenase 6.0
fatty acid elongase 6.0
acyl-CoA thioesterase 5.9
sterol carrier protein 5.9
aminocarboxymuconate-semialdehyde decarboxylase 5.9
more...
Compound
Dienestrol diacetate 11.2
Calcion 10.2
2-acetyl-1,3-cyclopentanedione 9.2
2,2',4,4',5,5'-Hexachlorobiphenyl 8.8
Mepanipyrim 8.7
Turinabol 8.6
Ouabagenin 8.6
Wuweizisu C 8.6
3,4,3',4'-Tetrachlorobiphenyl 8.6
Eriocitrin 8.4
C20H30O3 8.2
Ginkgolide C 8.2
atropic acid 8.0
Scopolin 8.0
9(S)-HODE 8.0
Saponarin 8.0
Thyronine 7.7
Sennoside A 7.6
Oil Red O 7.6
DJP 7.6
Coumarin 7 7.6
Coumarin 7 7.5
cholesta-3,5-dien-7-one 7.5
Oil Red O 7.4
cholesta-4,6-dien-3-one 7.4
Acetylshikonin 7.3
Ginkgolide C 7.3
Norephedrine 7.3
Ammonium pyrrolidine dithiocarbamate 7.2
Raspberry ketone 7.1
Rhaponticin 7.1
Ethionine 7.0
cholestane-3beta,5alpha,6beta-triol 7.0
Ruscogenin 7.0
Adrenic acid 7.0
6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde 6.8
Coniferaldehyde 6.8
Rubratoxin B 6.8
2,4,6-trihydroxybenzaldehyde 6.8
Oil Red 6.7
more...