Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0015695 (
fatty liver
)
13,941
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
The purpose of this study was to establish the normal range of serum apolipoprotein B-100 (
APO B-100
) concentration in clinically normal cattle, and to assess its abnormalities with clinical diseases. We measured the serum concentration of
APO B-100
in cattle of varying ages, breeds and sex, maintained under normal field conditions. Blood samples were obtained from 735 apparently healthy cattle and 146 cows with various diseases. The concentration of serum
APO B-100
in cattle was assayed by the single radial immunodiffusion method. The concentration of serum
APO B-100
in healthy adult breeding bulls (mean +/- SD: Holstein; 101 +/- 46 microg/ml, Japanese Black; 106 +/- 46 microg/ml) was significantly (P<0.001) lower than that in cows (Holstein; 259 +/- 63, Japanese Black; 210 +/- 46 microg/ml), while that of
APO B-100
in steers (Holstein; 290 +/- 86 microg/ml, Japanese Black; 302 +/- 90 microg/ml) was similar to the level in cows. The concentration of serum
APO B-100
in cattle varied with sex and breed.
APO B-100
concentration in cattle was decreased in association with metabolic disorders such as ketosis, displaced abomasum and
fatty liver
. From these results, it is assumed that the level of serum
APO B-100
will be applied to diagnosis of metabolic diseases in cattle.
...
PMID:Serum apolipoprotein B-100 concentrations in healthy and diseased cattle. 927 55
