Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0015695 (fatty liver)
 13,941 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A placebo-controlled double-blind study of 30 patients with advanced chronic fatty liver was intended to show how far treatment with a liver preparation, in this case Hepavis, is superior to alcohol abstinence alone. Examination of the laboratory parameters, especially of gamma GT shows that treatment with Hepavis with simultaneous withdrawal of alcohol produces a rapid normalization or improvement of the laboratory findings and consequently an accelerated improvement in the course of the disease. This leads to the conclusion that the pathological activity of the liver cell is reduced more quickly by the constituents of Hepavis than without suitable therapy, and that a more favorable prognosis for the fatty liver as a potential precurser of cirrhosis is to be attained. Not only is elimination of the lipogenic factor, alcohol, essential in the treatment of fatty liver, but also treatment with hepatotropic substances.
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PMID:[Treatment of alcoholic toxic fatty liver. A placebo-controlled trial with hepavis (author's transl)]. 11 Oct 85

During the therapy of fatty liver (resp. fatty liver hepatitis) the additional application of Hepavis besides the prohibition of alcohol does not have any advantages in comparison to an additional application of a placebo. So the significant decrease of the fat content of the liver under those circumstances seems to be only the consequence of lacking alcohol consume, but not a specific effect of Hepavis. Consequently the treatment of alcoholtoxic fatty liver can be no other than to avoid alcohol, one of the most important causes of illness nowadays.
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PMID:[Does Hepavis have value in the therapy of fatty liver caused by alcohol poisoning?]. 265 94