Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0015695 (fatty liver)
 13,941 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Pediatric gastroenterology, just as all fields within pediatrics, focuses on the unique needs of children ranging from infancy to adolescence. Although there is some overlap between adult gastroenterology and pediatric gastroenterology, these are 2 distinct fields of medicine that address the specific health care needs of the demographics they serve. The purpose of this article is to address several medical issues that have a particular importance to the pediatric population. The 5 main topics of discussion are magnet ingestion, cannabinoid hyperemesis syndrome, obesity and how it pertains to fatty liver disease, hepatitis B immunization status in the inflammatory bowel disease population, and irritable bowel syndrome. There is also a brief discussion regarding the transitioning process of our patients to adult medicine.
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PMID:Update in adolescent gastroenterology. 2370 29

Medical and recreational cannabis use has increased dramatically over the last decade, resulting from mainstream cultural acceptance and legalization in several countries worldwide. Cannabis and its derivatives affect many gastrointestinal processes via the endocannabinoid system (ECS). The ECS influences gastrointestinal homeostasis through anti-inflammatory, anti-nociceptive, and anti-secretory effects. Some gastrointestinal disorders might therefore be treated with cannabinoids. Despite numerous studies in cell lines and animals, few human studies have evaluated the therapeutic effects of cannabinoids. Cannabis' schedule 1 drug status has limited its availability in research; cannabis has been legalized only recently, in some states, for medicinal and/or recreational use. Cannabinoids can alleviate chemotherapy-induced nausea and emesis and chronic pain. Studies have demonstrated the important roles of the ECS in metabolism, obesity, and nonalcoholic fatty liver disease and the anti-inflammatory effects of cannabis have been investigated in patients with inflammatory bowel diseases. Despite its potential benefits, undesired or even detrimental effects of cannabis can limit its use. Side effects such as cannabinoid hyperemesis syndrome affect some users. We review the ECS and the effects of cannabis and its derivatives on gastrointestinal and hepatic function in health and disease.
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PMID:Role of Cannabis and Its Derivatives in Gastrointestinal and Hepatic Disease. 3233 10