Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0015695 (
fatty liver
)
13,941
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Pertussis
toxin markedly affects lipid metabolism in hamsters. The toxin induces a time-dependent and dose-dependent accumulation of triacylglycerols in the liver (
fatty liver
) and moderate increases in cholesterol and phospholipids. These toxin produced dramatic increases in the amounts of triacylglycerols, free fatty acids and ketone bodies in the serum and small increases in cholesterol and phospholipids. It is suggested that an enhanced and unregulated lipolysis may play a key role in the induction of these alterations by the toxin.
...
PMID:Pertussis toxin induces fatty liver, hyperlipemia and ketosis in hamsters. 362 15
