Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0015674 (chronic fatigue syndrome)
2,978 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 195
cytokine 87
Mol 57
CSF 50
gut 41
CD4 36
ATP 29
IL-6 28
CD8 27
interferon 25
tumor necrosis factor 24
MRI 22
RNase L 21
ACTH 20
HPA 19
insulin 19
TNF 19
Gen 19
lipopolysaccharide 18
IL-10 18
fur 18
IFN 18
IgA 17
gag 17
beta-endorphin 16
natural killer cell 16
B19 15
HLA 13
TNF-alpha 13
C-reactive protein 13
glucocorticoid receptor 13
env 12
growth hormone 12
Cytokine 12
ICD 12
IL-2 12
prolactin 11
catalase 11
lymphoid 11
IL-4 11
interferon-gamma 10
GSH 10
LPS 10
She 9
CRH 9
Pol 9
Pseudomonas 9
albumin 9
superoxide dismutase 9
IL-8 9
ANOVA 8
CD16 8
HLA-DR 8
collagen 8
5-hydroxytryptamine 8
NMR 8
creatine kinase 7
interleukin-10 7
CD56 7
IL-1 7
serotonin transporter 7
CD38 7
interleukin-6 7
IgG3 7
pituitary adenylate cyclase-activating polypeptide 7
thymus 7
interleukin-2 7
reserved 7
IFN-gamma 7
CD11b 6
CRP 6
GABA 6
REM 6
xenobiotic 6
nitric oxide synthase 6
vasoactive intestinal peptide (VIP) 6
CTX 6
5-HTTLPR 6
Mil 6
p53 6
more...
Disease
chronic fatigue syndrome 2978
fibromyalgia 378
depression 344
multiple sclerosis 121
Epstein 111
irritable bowel syndrome 103
cancer 102
leukemia 89
virus infection 84
cognitive impairment 81
chronic pain 71
major depressive disorder 69
prostate cancer 66
mental illness 64
influenza 55
HIV 50
sleep disorders 46
infectious mononucleosis 41
infectious diseases 40
rheumatoid arthritis 40
diabetes 39
Beard 38
sleep disturbances 38
asthma 34
systemic lupus erythematosus 34
migraine 34
cytomegalovirus 34
AIDS 33
schizophrenia 33
Parkinson's disease 30
posttraumatic stress disorder 30
encephalopathy 28
encephalitis 28
Alzheimer's disease 27
autoimmune disease 27
herpes 26
Lyme disease 26
anxiety disorders 26
EBV infection 25
lymphadenopathy 24
tumor 23
confusion 23
hypertension 23
Syndrome 23
immunodeficiency 22
obesity 20
HPA 19
polio 19
chronic disease 18
sick building syndrome 18
lupus 17
psychiatric diagnosis 17
arthritis 17
meningitis 16
autism 16
stroke 16
parvovirus 16
psychological distress 16
dementia 16
psychological stress 16
lupus 15
sleep apnea 15
Mycoplasma 15
neurological disease 15
cold 15
herpes simplex 14
hepatitis B 14
interstitial cystitis 14
metabolic syndrome 13
neuroticism 13
pneumonia 13
Infection 12
psychosis 12
Brucella abortus 12
cardiovascular disease 12
osteoarthritis 12
dysautonomia 12
myopathy 12
ICD 12
epilepsy 12
more...
Symptom
fatigue 1078
pain 270
Ill 102
headache 98
myalgia 97
exhaustion 47
weakness 42
mental fatigue 31
arthralgia 31
insomnia 30
sleepiness 27
sore throat 24
syncope 22
stigma 18
seizures 13
asthenia 12
dizziness 12
diarrhea 11
discomfort 10
hypersomnia 10
nausea 9
abdominal pain 9
chest pain 8
anorexia 8
low back pain 8
generalized pain 8
memory loss 7
chills 7
discomfort 7
ataxia 7
erythema 6
Depressive symptoms 6
alexithymia 6
anesthesia 6
pelvic pain 6
dyspnea 6
lethargy 5
lightheadedness 5
back pain 5
forgetfulness 4
cough 4
spasm 3
bladder pain 3
Cancer Fatigue 3
facial pain 3
acute stress 3
dysuria 3
despair 3
agitation 3
shortness of breath 3
vertigo 3
photophobia 3
vomiting 3
hypocapnia 2
paresis 2
hemiplegia 2
overweight 2
paresthesia 2
hyperesthesia 2
body pain 2
Joint hypermobility 2
constipation 2
night sweats 2
hyperacusis 2
tinnitus 2
dystonia 2
rhinorrhea 2
dry eye 2
lassitude 2
Decreased activity 2
blurred vision 2
myoclonus 2
snoring 2
orofacial pain 2
atypical chest pain 1
adenitis 1
cachexia 1
excessive sweating 1
splenomegaly 1
catatonia 1
more...
Drug
CFS 639
CSF 54
IL-2 12
ascorbate 11
IFN-gamma 7
Asthma 7
CTX 6
Bifidobacterium 6
CTX 6
CTX 6
CMZ 5
CEZ 5
Fraction 5
CPZ 5
CMX 5
AMK 4
LMOX 4
G-CSF 4
CFX 3
CZX 3
MRC 3
Modafinil 3
ROS 3
caffeine 3
AZT 2
p75 2
CTM 2
Posture 2
lysine 2
CET 2
CAZ 2
CTM 2
ROC 2
BH4 2
Moclobemide 2
Vitamin E 2
IPM 2
OFLX 2
Monit 2
AZT 2
Dermatol 2
Portal 2
CEX 1
Alferon N 1
ZnO 1
NaI 1
Ethanol 1
CXM 1
Rituximab 1
PPA 1
CCL 1
Orphan 1
Valganciclovir 1
AMC 1
Elm 1
Sulpiride 1
Spectrum 1
Epivir 1
CTT 1
Glutathione 1
Acyclovir 1
NADH 1
Midodrine 1
citric acid 1
Check 1
Glycyrrhiza 1
Gel 1
Ginseng 1
CER 1
niacin 1
Jujube 1
Alanine 1
TEL 1
Ganciclovir 1
Silica 1
OMP 1
ETS 1
MAP 1
Spectrum 1
Isoprinosine 1
more...
Enzyme
furin 18
reverse transcriptase 12
protein kinase 11
catalase 11
superoxide dismutase 9
pyruvate dehydrogenase 8
ERK 8
creatine kinase 7
pyruvate dehydrogenase 6
pyruvate dehydrogenase 6
adenylate cyclase 5
elastase 5
RNase 4
neutrophil elastase 4
RNase 4
DNA polymerase 4
glutathione peroxidase 4
RNA polymerase 3
mitogen-activated protein kinase 3
transcriptase 3
MCS 3
luciferase 3
renin 3
proteasome 3
AMP-activated protein kinase 3
cholinesterase 3
lysozyme 3
citrate synthase 3
lactate dehydrogenase 3
ACS 3
acetylcholinesterase 3
ribonuclease 2
thrombin 2
ribonuclease 2
indoleamine 2,3-dioxygenase 2
topoisomerase 2
cytochrome oxidase 2
topoisomerase 2
STR 2
CPT 2
glutathione reductase 2
complex I 2
monoamine oxidase 2
NO synthase 2
ATPase 2
beta-galactosidase 1
myosin ATPase 1
succinic semialdehyde dehydrogenase 1
TOR 1
nitrate reductase 1
aconitase 1
phosphorylase 1
invertase 1
FFT 1
plasmin 1
malate dehydrogenase 1
CPM 1
nitrate reductase 1
lipase 1
asparaginase 1
endonuclease 1
beta-glucuronidase 1
AMPK 1
nitrate reductase 1
m-calpain 1
glutaminase 1
chaperonin 1
PTA 1
proteinase K 1
NADPH oxidase 1
nitrate reductase 1
protein kinase C 1
thymidylate synthase 1
NADPH oxidase 1
nitrate reductase 1
myosin light chain kinase 1
deaminase 1
xanthine oxidase 1
nitrate reductase 1
sucrase 1
more...
Compound
Clin 321
Dec 196
DNA 123
oxygen 47
glucose 34
ATP 29
water 29
tryptophan 26
nitric oxide 25
tryptophan 22
ACTH 21
tryptophan 21
tryptophan 21
calcium 20
TNF 19
5-HT 18
sodium 16
phosphate 15
DSM 15
zinc 12
aluminum 11
GSH 10
nitrogen 10
L-carnitine 10
Cortisol 10
sulfate 10
GSH 10
glutamate 9
hydrogen 9
creatinine 8
BMC 8
coenzyme Q10 8
iron 8
AMP 8
DHA 8
neopterin 8
mercury 8
urea 7
phosphocreatine 7
CO2 7
hydroxide 7
tyrosine 6
potassium 6
CTX 6
noradrenaline 6
GABA 6
cysteine 6
GABA 6
serine 6
Carnitine 5
methionine 5
adenylate 5
CPZ 5
SDS 5
MIC 5
phosphorus 5
TSH 5
vitamin D 5
ammonia 5
TCA 5
Chlorpromazine 5
Phe 4
Poly I 4
glutamine 4
N-acetylcysteine 4
ANA 4
salt 4
alanine 4
R 2010 4
arginine 4
ANA 4
Mg2+ 4
acetate 4
gamma-aminobutyric acid 4
ACS 3
succinic acid 3
palmitic acid 3
nickel 3
asparagine 3
TOF 3
more...