Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0015674 (chronic fatigue syndrome)
 2,978 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 195
cytokine 87
Mol 57
CSF 50
gut 41
CD4 36
ATP 29
IL-6 28
CD8 27
interferon 25
tumor necrosis factor 24
MRI 22
RNase L 21
ACTH 20
TNF 19
HPA 19
Gen 19
insulin 19
fur 18
IFN 18
lipopolysaccharide 18
IL-10 18
IgA 17
gag 17
beta-endorphin 16
natural killer cell 16
B19 15
HLA 13
TNF-alpha 13
glucocorticoid receptor 13
C-reactive protein 13
env 12
IL-2 12
Cytokine 12
growth hormone 12
ICD 12
IL-4 11
lymphoid 11
catalase 11
prolactin 11
LPS 10
interferon-gamma 10
GSH 10
albumin 9
CRH 9
IL-8 9
She 9
superoxide dismutase 9
Pol 9
Pseudomonas 9
5-hydroxytryptamine 8
collagen 8
CD16 8
ANOVA 8
HLA-DR 8
NMR 8
CD56 7
interleukin-10 7
IFN-gamma 7
thymus 7
IL-1 7
pituitary adenylate cyclase-activating polypeptide 7
serotonin transporter 7
interleukin-2 7
interleukin-6 7
reserved 7
creatine kinase 7
IgG3 7
CD38 7
CRP 6
CD20 6
GABA 6
Mil 6
vasoactive intestinal peptide (VIP) 6
nitric oxide synthase 6
pyruvate dehydrogenase 6
CTX 6
5-HTTLPR 6
COPE 6
p53 6
CD11b 6
MRS 6
REM 6
Gag 6
xenobiotic 6
SCL 5
p24 5
CD69 5
adenylate cyclase 5
IL-1 beta 5
chemokine 5
MIC 5
vasopressin 5
perforin 5
leptin 5
2-5A synthetase 5
NHS 5
San 5
CD25 5
SDS 5
AMP 5
TCA 5
polypeptide 5
ferritin 5
enigma 5
interferon-alpha 5
CPZ 5
thyroid hormone 5
mast cell 5
5-HT2A 4
somatostatin 4
P300 4
granulocyte colony-stimulating factor 4
HNE 4
eotaxin 4
DNA polymerase 4
CD19 4
calcitonin 4
APA 4
GM-CSF 4
muscle protein 4
vasoactive intestinal peptide 4
c-fms 4
insulin-like growth factor I 4
G-CSF 4
p40 4
hemoglobin 4
adrenocorticotropic hormone 4
IL-7 4
ANA 4
tumor necrosis factor alpha 4
erythroid 4
IL-5 4
Env 4
CO2 4
glutathione peroxidase 4
Prolactin 4
CD57 4
RANTES 4
substance P 4
B12 4
IgE 4
olfactory 4
IL-17F 4
COX-2 4
transforming growth factor-beta 4
H. influenzae 3
granulocyte 3
NIR 3
ROS 3
AVP 3
Era 3
CXCL9 3
IL-13 3
insulin-like growth factor 3
renin 3
ADP 3
citrate synthase 3
PKR 3
TOF 3
more...
Disease
chronic fatigue syndrome 2978
fibromyalgia 378
depression 344
multiple sclerosis 121
Epstein 111
irritable bowel syndrome 103
cancer 102
leukemia 89
virus infection 84
cognitive impairment 81
chronic pain 71
major depressive disorder 69
prostate cancer 66
mental illness 64
influenza 55
HIV 50
sleep disorders 46
infectious mononucleosis 41
rheumatoid arthritis 40
infectious diseases 40
diabetes 39
sleep disturbances 38
Beard 38
systemic lupus erythematosus 34
cytomegalovirus 34
asthma 34
migraine 34
schizophrenia 33
AIDS 33
Parkinson's disease 30
posttraumatic stress disorder 30
encephalitis 28
encephalopathy 28
autoimmune disease 27
Alzheimer's disease 27
herpes 26
Lyme disease 26
anxiety disorders 26
EBV infection 25
lymphadenopathy 24
Syndrome 23
tumor 23
hypertension 23
confusion 23
immunodeficiency 22
obesity 20
HPA 19
polio 19
chronic disease 18
sick building syndrome 18
arthritis 17
lupus 17
psychiatric diagnosis 17
autism 16
psychological stress 16
dementia 16
psychological distress 16
stroke 16
meningitis 16
parvovirus 16
cold 15
Mycoplasma 15
sleep apnea 15
neurological disease 15
lupus 15
interstitial cystitis 14
herpes simplex 14
hepatitis B 14
neuroticism 13
metabolic syndrome 13
pneumonia 13
cardiovascular disease 12
psychosis 12
Infection 12
ICD 12
Brucella abortus 12
dysautonomia 12
epilepsy 12
osteoarthritis 12
myopathy 12
affective disorder 12
sudden infant death syndrome 11
myofasciitis 11
Multiple chemical sensitivity 11
carcinoma 11
Q fever 11
somatization disorder 11
narcolepsy 11
hepatitis C 11
rash 11
emotional distress 10
suicide 10
chronic hepatitis 10
mimicry 10
brain dysfunction 10
GSH 10
Gulf War Syndrome 10
clinical depression 10
sepsis 10
Borna disease 9
neuromyasthenia 9
hepatitis 9
sepsis 9
restless legs syndrome 9
regional pain syndrome 8
disabling disease 8
meningoencephalitis 8
West 8
viremia 8
Best 8
memory impairment 7
SAD 7
heart disease 7
neuropathy 7
hysteria 7
encephalomyelitis 7
coronary artery disease 7
adrenal insufficiency 7
endocarditis 7
hyperphagia 7
amyotrophic lateral sclerosis 7
allergic rhinitis 7
lymphoma 7
osteoporosis 7
celiac disease 7
anemia 7
breast cancer 7
pharyngitis 6
psoriasis 6
psychosomatic disorders 6
sexual dysfunction 6
Addison's disease 6
CTX 6
heart failure 6
chronic obstructive pulmonary disease 6
latent infection 6
panic disorder 6
MRS 6
hypoglycemia 6
bipolar disorder 6
PSS 6
Hodgkin's disease 6
endometriosis 6
cystic fibrosis 6
organic disease 6
Addison's disease 6
ADHD 5
tension headache 5
ulcerative colitis 5
panic attacks 5
Sleep disturbance 5
cirrhosis 5
neurocirculatory asthenia 5
inflammatory bowel disease 5
carcinogenesis 5
movement disorder 5
Sjogren's syndrome 5
renal failure 5
cognitive deficit 5
autonomic neuropathy 5
more...
Symptom
fatigue 1078
pain 270
Ill 102
headache 98
myalgia 97
exhaustion 47
weakness 42
arthralgia 31
mental fatigue 31
insomnia 30
sleepiness 27
sore throat 24
syncope 22
stigma 18
seizures 13
dizziness 12
asthenia 12
diarrhea 11
hypersomnia 10
discomfort 10
nausea 9
abdominal pain 9
chest pain 8
anorexia 8
low back pain 8
generalized pain 8
chills 7
discomfort 7
ataxia 7
memory loss 7
alexithymia 6
Depressive symptoms 6
anesthesia 6
pelvic pain 6
erythema 6
dyspnea 6
back pain 5
lightheadedness 5
lethargy 5
cough 4
forgetfulness 4
agitation 3
photophobia 3
Cancer Fatigue 3
despair 3
dysuria 3
acute stress 3
facial pain 3
shortness of breath 3
spasm 3
vertigo 3
bladder pain 3
vomiting 3
constipation 2
hypocapnia 2
paresis 2
paresthesia 2
body pain 2
Joint hypermobility 2
Decreased activity 2
lassitude 2
rhinorrhea 2
hyperacusis 2
night sweats 2
tinnitus 2
dystonia 2
blurred vision 2
dry eye 2
hemiplegia 2
overweight 2
hyperesthesia 2
orofacial pain 2
myoclonus 2
snoring 2
decreased appetite 1
physical exhaustion 1
abdominal discomfort 1
adenitis 1
cachexia 1
menopausal symptoms 1
excessive sweating 1
splenomegaly 1
catatonia 1
neck pain 1
polymyalgia 1
pleuritic chest pain 1
chronic constipation 1
apathy 1
Vulvodynia 1
stomach pain 1
neurological disability 1
angina 1
chronic cough 1
spasticity 1
Chronic pelvic pain 1
dysarthria 1
aphonia 1
abnormal reflex 1
Visual symptoms 1
Cutaneous anergy 1
tremor 1
Fluctuation 1
febricula 1
acidity 1
Spots 1
joint stiffness 1
fever of unknown origin 1
shoulder pain 1
disturbed balance 1
flushing 1
analgesia 1
Hudson 1
ophthalmoplegia 1
limb pain 1
distraction 1
collapse 1
glossodynia 1
incoordination 1
precordial pain 1
frequent urination 1
eye pain 1
atypical chest pain 1
hyperoxia 1
hepatomegaly 1
chronic back pain 1
situational stress 1
hoarseness 1
nerve root irritation 1
neck stiffness 1
hot flashes 1
masculinization 1
presyncope 1
hypothermia 1
bone pain 1
Drug
CFS 639
CSF 54
IL-2 12
ascorbate 11
IFN-gamma 7
Asthma 7
Bifidobacterium 6
CTX 6
CTX 6
CTX 6
Fraction 5
CEZ 5
CMZ 5
CPZ 5
CMX 5
LMOX 4
AMK 4
G-CSF 4
CZX 3
CFX 3
MRC 3
Modafinil 3
caffeine 3
ROS 3
CAZ 2
CTM 2
CTM 2
CET 2
AZT 2
ROC 2
lysine 2
Posture 2
Vitamin E 2
BH4 2
p75 2
AZT 2
IPM 2
OFLX 2
Monit 2
Moclobemide 2
Dermatol 2
Portal 2
CEX 1
Alferon N 1
ZnO 1
NaI 1
Ethanol 1
CXM 1
Rituximab 1
PPA 1
CCL 1
Orphan 1
Valganciclovir 1
AMC 1
Elm 1
Spectrum 1
NaI 1
Naltrexone hydrochloride 1
Epivir 1
NADH 1
CTT 1
Glutathione 1
Acyclovir 1
NaI 1
Gel 1
TAC 1
citric acid 1
vitamin E 1
Midodrine 1
Glycyrrhiza 1
DBS 1
CPM 1
Jujube 1
Sulpiride 1
Retinoic acid 1
Silica 1
niacin 1
CFT 1
Ganciclovir 1
Alanine 1
TEL 1
TiO2 1
Check 1
OMP 1
ETS 1
MAP 1
Spectrum 1
Isoprinosine 1
NaI 1
Ginseng 1
ampicillin 1
CER 1
Pregabalin 1
Agomelatine 1
DEX 1
Leaf 1
IFN-beta 1
Clonidine 1
Horizon 1
Biopolymers 1
Albumin 1
ENT 1
Enzyme
furin 18
reverse transcriptase 12
catalase 11
protein kinase 11
superoxide dismutase 9
pyruvate dehydrogenase 8
ERK 8
creatine kinase 7
pyruvate dehydrogenase 6
pyruvate dehydrogenase 6
elastase 5
adenylate cyclase 5
DNA polymerase 4
RNase 4
RNase 4
neutrophil elastase 4
glutathione peroxidase 4
cholinesterase 3
renin 3
proteasome 3
MCS 3
lactate dehydrogenase 3
acetylcholinesterase 3
citrate synthase 3
mitogen-activated protein kinase 3
luciferase 3
transcriptase 3
lysozyme 3
ACS 3
AMP-activated protein kinase 3
RNA polymerase 3
monoamine oxidase 2
topoisomerase 2
thrombin 2
cytochrome oxidase 2
indoleamine 2,3-dioxygenase 2
NO synthase 2
ribonuclease 2
STR 2
glutathione reductase 2
topoisomerase 2
complex I 2
ribonuclease 2
CPT 2
ATPase 2
beta-galactosidase 1
myosin ATPase 1
succinic semialdehyde dehydrogenase 1
TOR 1
nitrate reductase 1
aconitase 1
phosphorylase 1
invertase 1
FFT 1
plasmin 1
malate dehydrogenase 1
CPM 1
nitrate reductase 1
lipase 1
asparaginase 1
prostate-specific antigen 1
beta-glucuronidase 1
phosphodiesterase 1
nitrate reductase 1
m-calpain 1
chaperonin 1
PTA 1
proteinase K 1
NADPH oxidase 1
neutral sphingomyelinase 1
AMPK 1
factor C 1
nitrate reductase 1
endonuclease 1
deaminase 1
beta-lactamase 1
CEP 1
collagenase 1
granzyme B 1
protein kinase C 1
thymidylate synthase 1
NADPH oxidase 1
nitrate reductase 1
myosin light chain kinase 1
phospholipase C 1
glutaminase 1
thyroid peroxidase 1
GTP cyclohydrolase I 1
NOS 1
nitrate reductase 1
sucrase 1
peroxidase 1
xanthine oxidase 1
SCP 1
AMPK 1
cathepsin B 1
AMP deaminase 1
lactase 1
pyroglutamate aminopeptidase 1
serum carnosinase 1
CEP 1
bromelain 1
DNase 1
Alternating 1
transketolase 1
alpha-glucosidase 1
succinate dehydrogenase 1
CFI 1
aspartate aminotransferase 1
tryptophan hydroxylase 1
CCS 1
dUTPase 1
PRA 1
p100 1
MEK 1
Compound
Clin 321
Dec 196
DNA 123
oxygen 47
glucose 34
water 29
ATP 29
tryptophan 26
nitric oxide 25
tryptophan 22
ACTH 21
tryptophan 21
tryptophan 21
calcium 20
TNF 19
5-HT 18
sodium 16
phosphate 15
DSM 15
zinc 12
aluminum 11
L-carnitine 10
sulfate 10
GSH 10
nitrogen 10
GSH 10
Cortisol 10
hydrogen 9
glutamate 9
coenzyme Q10 8
BMC 8
DHA 8
neopterin 8
AMP 8
creatinine 8
iron 8
mercury 8
hydroxide 7
urea 7
phosphocreatine 7
CO2 7
CTX 6
noradrenaline 6
cysteine 6
GABA 6
GABA 6
serine 6
potassium 6
tyrosine 6
MIC 5
Carnitine 5
methionine 5
CPZ 5
Chlorpromazine 5
TSH 5
TCA 5
phosphorus 5
SDS 5
vitamin D 5
adenylate 5
ammonia 5
ANA 4
Mg2+ 4
Phe 4
acetate 4
glutamine 4
alanine 4
Poly I 4
arginine 4
R 2010 4
N-acetylcysteine 4
gamma-aminobutyric acid 4
ANA 4
salt 4
succinic acid 3
Adrenal 3
TOF 3
nickel 3
formaldehyde 3
NMDA 3
ACS 3
succinic acid 3
Lactate 3
caffeine 3
Cardiol 3
succinic acid 3
cadmium 3
6-12 3
palmitic acid 3
copper 3
asparagine 3
ADP 3
Off 3
ACS 3
ADP 3
succinic acid 3
succinic acid 3
ethanol 3
ADP 3
palmitic acid 3
Coenzyme Q10 3
benzamide 3
Malondialdehyde 3
methane 3
formaldehyde 3
Salt 3
His 3
bromide 3
PDQ 2
fluorine 2
CAM 2
aldosterone 2
EDTA 2
CAP 2
prostacyclin 2
Abbott 2
proline 2
Isoproterenol 2
glutamic acid 2
NFS 2
Agar 2
pyrimidine 2
threonine 2
pyrimidine 2
lysine 2
CAT 2
5-oxoproline 2
silicon 2
phosphoric acid 2
Insulin 2
isopropanol 2
myristic acid 2
retinoic acid 2
silver 2
Vitamin E 2
ornithine 2
NAD 2
Cholesterol 2
ornithine 2
Carbon 2
toluene 2
Lactic acid 2
Epigallocatechin gallate 2
Benzene 2
5-HIAA 2
3-methylhistidine 2
diacetate 2
nitrate 2
beta-alanine 2
EDS 2
ornithine 2
carbonate 2
Bupropion 2
ornithine 2
PPA 2
CAP 2
AZT 2
Melatonin 2
nicotinamide 2
Dexamethasone 2
more...