Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0015674 (
chronic fatigue syndrome
)
2,978
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
An immuno-enzyme assay of
NSE
and MBP in the cerebrospinal fluid (
CFS
) and blood serum of rats during the development of acute experimental autoimmune encephalomyelitis revealed the increase of
NSE
, a neuronal marker, and MBP, a marker for myelin. The investigation has shown that the increased level of
NSE
in CSF was prior to the increased concentration of MBP. The changes of these neurospecific proteins (NSP) in the serum were not the same as in the CSF. The analysis of the ratio between NSP concentrations in CSF to serum revealed the initial marked decrease of BBB permeability to MBP but not to
NSE
.
...
PMID:[Elimination of NSE and MBP into cerebrospinal fluid and blood in acute experimental autoimmune encephalomyelitis]. 1989 10
