Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0015674 (
chronic fatigue syndrome
)
2,978
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Gamma-aminobutyric acid is a major inhibitory neurotransmitter in the central nervous system. GABA metabolism is dependent on the activity of three enzymes: glutamic acid decarboxylase, GABA-transaminase and
succinic semialdehyde dehydrogenase
. Decreased activity of these enzymes may cause many neurological syndromes, such as stiff-person syndrome,
chronic fatigue syndrome
, anxiety disorders and seizures. This article is a review of most important problems related to an impairment of GABA metabolism.
...
PMID:[Gamma-aminobutyric acid--metabolism and its disorders]. 1902
