Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0015674 (
chronic fatigue syndrome
)
2,978
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Buspirone is known to stimulate prolactin release. Clinical studies (e.g. in
chronic fatigue syndrome
) suggest that the response may be influenced by baseline cortisol levels. We conducted a double-blind placebo-controlled study to examine the relationship between the prolactin response to buspirone challenge and baseline cortisol level. Fifty healthy volunteers took part in the study. Buspirone was found to consistently elevate
PRL
levels above those seen following placebo administration. The
PRL
response as measured by area under the curve was highly correlated with the baseline cortisol level.
...
PMID:Impact of cortisol on buspirone stimulated prolactin release: a double-blind placebo-controlled study. 1150 Feb 55
