Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0015674 (
chronic fatigue syndrome
)
2,978
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
The novel human gammaretrovirus xenotropic murine leukemia virus-related virus (XMRV), originally described in prostate cancer, has also been implicated in
chronic fatigue syndrome
(
CFS
). When later reports failed to confirm the link to
CFS
, they were often criticised for not using the conditions described in the original study. Here, we revisit our patient cohort to investigate the XMRV status in those patients by means of the original PCR protocol which linked the virus to
CFS
. In addition, sera from our
CFS
patients were assayed for the presence of xenotropic virus
envelope protein
, as well as a serological response to it. The results further strengthen our contention that there is no evidence for an association of XMRV with
CFS
, at least in the UK.
...
PMID:Investigation into the presence of and serological response to XMRV in CFS patients. 2140 77
