Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0015674 (
chronic fatigue syndrome
)
2,978
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
This paper explores the relationship between
chronic fatigue syndrome
(
CFS
) and psychiatric disorder, with special reference to neuropsychiatry, Topics reviewed include (1) epidemiological evidence of central disorder in
CFS
; (2) evidence from longitudinal studies of an interaction between vulnerability to
CFS
and psychiatric disorder; and (3) evidence from neuroimaging, neuropsychology, neurophysiology and neuroendocrinology of disordered CNS function in
CFS
. The most impressive evidence of CNS disturbance comes from neuroendocrinological studies, which suggest a role of
hypothalamic disorder
as a final common pathway for
CFS
. It is concluded that the equal and opposite tendencies of psychiatry to be 'brainless' and neurology to be 'mindless' have led to needless controversy over the nature of
CFS
. Now that the contributions of psychiatric disorder to
CFS
, and of neurobiological dysfunction to psychiatric disorder, are both established, it will be possible to make real advances in understanding the nature of
CFS
.
...
PMID:The neuropsychiatry of chronic fatigue syndrome. 849 Oct 99
