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Query: UMLS:C0015672 (fatigue)
 51,768 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Strength evaluation in neuromuscle disease is necessary to track the natural history of the disease, to understand its pathophysiology, to determine the efficacy of treatment, and, most importantly, to evaluate an experimental treatment regimen. This article describes the physiology of muscle activity, discusses fatigue, examines various testing methods, and suggests appropriate measurements to assess the neuromuscular patient's strength and endurance in a variety of clinical settings. The minimal amount of equipment necessary to follow patients with NMD is a stop watch, a goniometer, a hand-held dynamometer, a hand-grasp dynamometer, and a creative mind.
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PMID:Strength evaluation in neuromuscular disease. 355 Apr 13

Muscle fatigue and exercise intolerance are common and frequent symptoms complained by patients with neuromuscular disease. Muscle fatigue would occur when the intended physical activity can no longer be continued or is perceived as involving excessive effort and discomfort. Except for several rare myopathies with specific metabolic derangements leading to exercise-induced muscle fatigue, most studies fail to identify precise pathogenic mechanism of fatigue in this population of patients. On the other hand, apart from canonical examples of neuromuscular diseases, a number of conditions in which muscle apparatus can be involved is known to occur with high prevalence among certain people categories, such as elderly or people undergoing immobilization. In these cases exercise intolerance and muscle fatigue can be severely incapacitating in common daily activities. An objective and smart, unobtrusive techniques, able to objectively measure fatigue phenomenon, would be useful in monitoring muscle function in both NMD patients and patients with secondary skeletal muscle involvement. In this study, we report a novel, non-invasive assistive architecture for the elderly to assess muscle fatigue by biomedical sensors (surface electromyography) using wireless platform during exercise in an ergonomic platform.
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PMID:A personal monitoring architecture to detect muscular fatigue in elderly. 2318 38