Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0015672 (fatigue)
 51,768 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Discussions having lately raised the importance of rest in the treatment of viral hepatitis the authors report some studies made on the subject. They take into account 3 personal unpublished statistics analyzing the role of effort at 3 different stages -- in the acute phase, during convalescence and as an eventual factor producing aggravation. Although their results appear to be in contradiction with those found in American studies the authors show that the importance of rest in the initial phase is unanimously recognized and that there is no statistical evidence that such a prescription should be given up before the normalization of the main biological parameters. Furthermore though it is statistically proved that a certain activity between the 30th and 60th day does not affect the later course of the disease yet there is no element which allows to authorize the patient to resume his normal professionnal activity before the 60th day. Finally the lack of controlled studies does not allow any precise determination of the impact of effort in the determinism of an eventual aggravation. However according to the authors' experience physical tiredness can legitimately be suspected to have produced this aggravation in 47.06 % of cases of a secondarily aggravated hepatitis.
Sem Hop 1975 Mar 26
PMID:[Effect of rest on the course of viral hepatitis]. 17 63

Fatigue fractures of the foot are the commonest fatigue fractures, still called walking fractures or "stress fractures". Formerly, they were metatarsal in more than 80% of cases: over the last few years, the calcaneal localizations mainly predominate (more than 70%). The fatigue fractures formerly described almost always in soldiers after a long march, are in fact encountered at all ages, including children, and in both sexes. The diagnosis in usually easy, provided that one thinks of it. It depends on the history, on clinical examination with pain on palpation of the bone, on a bone scan which shows early hyperfixation, on radiological examination, in which signs appear later than on clinical examination, and the bone scan, thus X rays often have to be repeated. The treatment is simple. Relief of weight bearing is usually sufficient. Plaster is usually neither necessary nor useful. Prophylaxis consists of avoiding physical activity, especially prolonged walking without prior gradual training.
Sem Hop
PMID:[Fatigue fractures of the foot (author's transl)]. 611 44

Tiapride was used in 55 chronic alcoholics. It has a sedative effect on the anxiety, aggressiveness and agitation observed during the alcohol withdrawal syndrome. It is also effective against tremor, insomnia and fatigue. Fatigue or depression do not occur as side-effects. Tiapride induces a psychological feeling of wellbeing which is heightened by continuation of detoxication and general management.
Sem Hop
PMID:[Tiapride in detoxication of chronic alcoholics (author's transl)]. 627 32

Questionnaires calling for answers of yes or no were tested in the field of family medicine (125 questions) and in a hospital outpatient clinic (164 questions). In the hospital, results were not given to physicians before evaluation of the patient. In family medicine, 3 328 positive answers were given by 200 patients (average 17), against 3 439 and 115 (average 30) respectively in the hospital. As compared with questionnaires, conventional case-reports missed two out of three symptoms or antecedents, many of which were important. Examples are given. Such omissions were more frequent in males, and in some, specialties. They were not less frequent in common diseases. Unexpectedly, omissions were all the more numerous that patients already had more diagnoses. Filling the questionnaire took an average of 3.5 seconds per question. The opinion of patients was usually favorable. The duration of consultations was slightly increased when using the questionnaires. Questionnaires were useful: to patients, by reducing risks of omissions, fatigue of physicians and disparities between physicians; to physicians, by reducing risks of lawsuits. Economic results are complex. Acceptability is discussed. The initial reluctance of physicians can be overcome. From this experience, the number of questions can be brought down to 89.
Sem Hop 1984 Feb 23
PMID:[Value of the health questionnaire in family medicine and hospital consultation]. 632 67