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Query: UMLS:C0015672 (fatigue)
 51,768 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

It is an acknowledged fact that Iranian carpet weavers are subject to excessive fatigue. Earlier investigation has shown this to be largely due to a non-ergonomic body position while working at a traditional loom. It would appear that significantly increased production could be achieved by eliminating or reducing this fatigue. An Iranian engineer has attempted to do this by inventing a metal loom which takes ergonomic factors into consideration. The purpose of this study was to evaluate the effect of the new loom by comparing the productivity of two groups in Kerman, Iran: one using the new ergonomic loom and the other using the traditional loom. In preliminary investigations various factors were taken into account so that the two groups might be considered comparable. After several observations the average productivity of each weaver was calculated (according to knots per day). The results showed that the ergonomic loom had the highest productivity figures for both sexes and that increased productivity was directly related to the degree of comfort of the carpet weavers.
J Hum Ergol (Tokyo) 1976 Dec
PMID:Ergonomics in traditional Iranian industries. 103 Apr 44

Physique, muscle strength, and jump-step scores of female industrial workers, ages 17--34, were studied in relation to tenderness of shoulder muscles for five groups, (A) character display operators, (B) fluorescent lamp assemblers, (C) photographic film rolling workers, (D) teachers and nurses of handicapped children, and (E) office workers. No significant differences were found between the five groups in mean body height, body weight, and skinfold thickness, but mean knee extension force of groups A and C and mean back muscle strength of groups A, B, and C was significantly lower than that of group E. Workers of groups C and D with a low tenderness threshold of m. trapezius of 0.6 kg/cm2 or less had stiff shoulders more frequently and lower force levels of knee extension, back muscle, and upper arm abduction than those without tenderness. No similar tendency was found for groups B and E. Further, among workers with objective signs of occupational cervicobrachial disorder, there were few whose knee extension force or jump-step scores were above the averages of normal office workers. Shoulder muscles of such operators were revealed to be continuously contracted during operations. The possible effects of chronic fatigue due to repetitive operations on developing localized tenderness and occupational hazards are discussed.
J Hum Ergol (Tokyo) 1976 Dec
PMID:Shoulder muscle tenderness and physical features of female industrial workers. 103 Apr 53

Clinical, biochemical, haematological and erythrokinetic studies were performed on 63 adult males with prolonged lead exposure. Their most common symptoms and findings were abdominal pain (62%), gingival lead lines (48%), headache and/or dizziness (33%), muscle cramps (32%), anaemia (19%), and fatigue (18%). Colicky abdominal pain (27%) and gingival lead lines correlated with urinary lead excretion. Anaemia was mild, but more frequent in the subjects with the greatest urinary lead excretion. Other associated findings were: higher reticulocyte counts and more basophilic stippling of the RBCs, more sideroblasts and greater erythroid hyperplasia of the bone marrow, more reduction in 51Cr-tagged RBC survival time, smaller RBC mass, a more rapid plasma iron clearance, a greater plasma iron turnover and greater utilization of 59Fe in subjects with urinary lead excretion of greater than 100 microng/day in comparison with the remainder and normal controls. These findings suggest that minimal chronic exposure to lead causes an increased haemolysis with resulting increased production of erythrocytes.
Southeast Asian J Trop Med Public Health 1976 Dec
PMID:Chronic industrial exposure to lead in 63 subjects. I. Clinical and erythrokinetic findings. 103 Aug 53

The time course of phosphorylcreatine (PC) resynthesis in the human m. quadriceps femoris was studied during recovery from exhaustive dynamic exercise and from isometric contraction sustained to fatigue. The immediate postexercise muscle PC content after either form of exercise was 15-16% of the resting muscle content. The time course of PC resynthesis during recovery was biphasic exhibiting a fast and slow recovery component. The half-time for the fast component was 21-22s but this accounted for a smaller fraction of the total PC restored during recovery from the isometric contraction than after the dynamic exercise. The half-time for the slow component was in each case more than 170 s. After 2 and 4 min recovery the total amount of PC resynthesized after the isometric exercise were significantly lower than from the dynamic exercise. Occlusion of the circulation of the quadriceps completely abolished the resynthesis of PC. Restoration of resynthesis occurred only after release of occlusion.
Pflugers Arch 1976 Dec 28
PMID:The time course of phosphorylcreatine resynthesis during recovery of the quadriceps muscle in man. 103 9

In excised, curarized and massively stimulated fast-twitch mouse gastrocnemius muscles the early twitch tension enhancements (treppe) during 1/s activity between 10 and 36 degrees C increase and affect more contractions as temperature increases. Tension output eventually declines at a temperature-independent rate. Half-relaxation time lengthens below 25 degrees C and shortens above 25 degrees C. During 1/0.63s twitches half-relaxation time lengthens even at 25 degrees C. In slow-twitch soleus muscles activity decreases twitch tension and half-relaxation time regardless of temperature. Activity shortens contraction times in both muscles. Oxygen lack induced by NaN3 cannot account satisfactorily for these results. Activation is apparently more plastic in the gastrocnemius than in the soleus, and the relationship between the rates of their activation and relaxation processes and the temperature sensitivities of these rates also seem to differ. In both muscles caffeine can convert activity-induced shortened of half-relaxation times into prolongations. In the soleus this effect is more pronounced at 30 than at 25 degrees C. At high temperature and twitch rates caffeine reduces treppe amplitude and duration without affecting the eventual twitch tension decline in the gastrocnemius while it greatly accelerates twitch tension decline in the soleus. In both muscles intrafiber Ca2+ movements are apparently major determinants of fatigue behavior.
Pflugers Arch 1976 Dec 28
PMID:Fatigue and caffeine effects in fast-twitch and slow-twitch muscles of the mouse. 103 14

Elective hysterectomy has become culturally patterned as a normal part of the life cycle with more than half of all American women destined for hysterectomy if current rates continue. In keeping with this widespread acceptance, both women and their doctors frequently express satisfaction with the operation. The sequelae that do occur appear to be serious in only a few women, though more minor disturbances do appear in a sizable number. Repeated or controlled studies indicate that hysterectomy may yield problems for some women in the following areas: rejection by male partners, hot flushes after conservation of ovarian tissue, severe hot flushes after ovariectomy, long-term psychourinary problems, weight changes, lingering fatigue and prolonged convalescence, painful intercourse, depression, sleep disturbances, and other psychiatric symptoms. Prospective studies using matched control groups are needed which follow patients at least 2 years postoperatively, as repeated studies have shown "sleeper effect" after hysterectomy with sequelae developing after the first 6 months or even after 1 year. The impact of varying surgical techniques and the long-term endocrine impact of hysterectomy need to be detailed as well as further study undertaken on the psychosomatic sequelae.
Prim Care 1976 Dec
PMID:Reactions to hysterectomy: fact or fiction? 105 27

A 49-year-old woman had a six-week history of increasing shortness of breath and fatigue. X-ray films and pulmonary scans showed multiple areas of emboli, especially in the right lung. Treatment with heparin was unsuccessful, and although a repeat scan showed only slight changes, the patient's condition deteriorated. Acute pulmonary edema and ventricular tachycardia preceded her death. Autopsy revealed a primary intimal sarcoma with osteogenic elements arising in the posterior leaflet of the pulmonary valve and obstructing the main pulmonary artery and its right branch.
Arch Pathol Lab Med 1976 Dec
PMID:Primary intimal sarcoma of pulmonary valve and trunk with osteogenic sarcomatous elements. Report of a case considered to be pulmonary embolus. 106 72

1. One hundred patients with severe essential hypertension have been treated with minoxidil for a mean period of 8-4 months in a study involving eleven European centres. Seventy-two males and twenty-eight females were included in the group; the mean age was 55 years and the initial supine systolic and diastolic pressures averaged 212 (range 150-270) and 125 (range 90-150) mmHg respectively. 2. Reduction of supine diastolic pressure to less than 100 mmHg occurred in 94% of patients within 4 weeks. After the average follow-up period of 8-4 months the mean pressures were 151/91 mmHg. Concomitant therapy with beta-receptor-blocking agents and diuretics resulted in satisfactory control of heart rate and weight gain. 3. Side effects included increased hair growth, nausea, fatigue, rash and darkening of the skin. ECG showed mainly T-wave changes and echocardiographic examination indicated improved ventricular emptying.
Clin Sci Mol Med Suppl 1976 Dec
PMID:The use of minoxidil in the treatment of severe essential hypertension: a report on 100 patients. 107 84

Narcine brasiliensis electric organ was stimulated to fatigue in vivo. Electrical display of organ output and biochemical assay of bound acetylcholine (ACh) and ATP in isolated vesicles were used to assess the state of fatigue relative to denervated control organs of the same fish. A morphometric analysis of the fate of the synaptic vesicle populations in the nerve terminals was carried out. Statistically significant morphological changes in vesicle populations and plasma membranes were observed between control and fatigued electroplaque stacks from individual fish. Pooled data from several fish were used to evaluate the possible role of the different vesicle types in neurotransmission. Fatigue resulted in the loss of 49% of the total vesicle population and a 76% loss of vesicles with bound calcium (Ca). An approximately equivalent increase in the nerve-terminal plasma membrane area was measured. This was predominantly in the form of fingerlike protrusions and/or invaginations of the terminals which were present in the control organs but which were significantly increased by stimulation. Vesicle attachments to the nerve terminal membrane were reduced by 90%. This suggests that the failure in transmission may be due to reduction in the number of vesicles which are loaded with transmitter and can attach to the terminal membrane. The Ca-binding capacity of the lost vesicles was not transferred to the plasma membranes. This result was interpreted as support for the hypothesis that vesicle-bound ATP provides the Ca-binding site.
J Cell Biol 1975 Dec
PMID:Changes in cholinergic synaptic vesicle populations and the ultrastructure of the nerve terminal membranes of Narcine brasiliensis electron organ stimulated to fatigue in vivo. 120 24

Hyperaldosteronism due to aldosteronoma is a rare but potentially curable form of pediatric hypertension. We have presented a patient who had symptoms of enuresis and fatigue, and in whom the diagnosis was suggested by low serum potassium and persistent hypertension. Diagnosis was confirmed by increased plasma and urinary aldosterone and decreased plasma renin. The tumor was localized with the aid of adrenal venography and catheterization, which showed greatly increased plasma aldosterone levels in the right adrenal vein. The pathologic findings were totally reversed by right adrenalectomy. The clinical picture and results following surgical removal of aldosterone-producing tumors in six children are reviewed.
J Pediatr Surg 1975 Dec
PMID:Aldosteronoma in a child with localization by adrenal vein aldosterone: collective review of the literature. 120 77


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