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Query: UMLS:C0015672 (fatigue)
 51,768 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Laryngotracheobronchitis (LTB) continues to occur in epidemics necessitating many hospital admissions. A short barking cough, stridor with a crowing sound on inspiration, and retractions of the intercostal respiratory muscles are hallmarks of the disease. LTB is most frequently a viral disease causing acute inflammation of the subglottic area, the trachea, and the segmental bronchus. Increasing subglottic edema and generalized fatigue of patients with this disease can cause progression of airway obstruction. Respiratory and cardiac arrest follow unless an immediate airway is established. The management of LTB is primarily medical and consists of moist air, sedation, close observation, and occasionally antibiotics. Patients with respiratory difficulties severe enough to require intubation should undergo direct laryngoscopy and bronchoscopy to rule out other causes of airway obstruction.
J Otolaryngol 1979 Dec
PMID:Laryngotracheobronchitis--a continuing challenge in child health care. 52 58

It is classically considered that cochlear fatigue and acoustic trauma occur when intensity is such that the ear is saturated, i.e. when the microphonic potential fails to increase in a linear fashion in relation to intensity and when distorsion appears. The present report concerns a study in the guinea pig of the relationship between the non-linearity of microphonic responses, and their fatigability. The results show that fatigability is related not only to non-linearity but also to the asymmetry of responses. The asymmetry of microphonic responses may be interpreted as reflecting an asymmetrical ionic flow at the upper pole of hair cells, resulting in an accumulation of potassium ions within and around hair cells and thereby creating a depression of responses.
Ann Otolaryngol Chir Cervicofac 1979 Dec
PMID:[Relationship between cochlear fatigue and the asymmetrical non-linearity of microphonic responses in the guinea pig (author's transl)]. 53 88

A comparison was made between losses of auditory sensitivity after a fatiguing sound exposure of the ear in two groups of subjects: audiometrically normal subjects and subjects with early acoustic trauma. Subjects with cochlear impairment sustained an auditory loss apparently less than that of normal subjects when this loss is measured at threshold level. However, at supraliminal levels the loss of sensitivity, as measured here, would seem to be equal in both groups of subjects. In fact, the dynamics of sonic variations, already reduced by the cochlear impairment, is even further decreased by the effects of fatigue.
Ann Otolaryngol Chir Cervicofac 1979 Dec
PMID:[Auditory fatigue in individuals having sustained an acoustic trauma (author's transl)]. 53 89

The effects of iron-deficiency anaemia on workers productivity were studied in a tea plantation in Sri Lanka. The quantity of tea picked per day was studied before and after iron supplementation or placebo treatment. After one month's treatment significantly more tea was picked when the haemoglobin (Hb) concentration was increased by iron supplementation than when it was not. The degree of improvement was greater in more-anaemic subjects (those with concentrations of 6.0-9.0 g Hb/dl). The level of physical activity of anaemic subjects in their everyday environment was also recorded for four or 24 hours continuously both before and after treatment. After three weeks these levels was significantly greater in the iron-treated than matched placebo-treated subjects. The economic implications of increased work productively with iron treatment are evident, particularly in developing countries. These results also provide strong evidence for the clinical impression that people with iron-deficiency anaemia suffer from tiredness and weakness.
Br Med J 1979 Dec 15
PMID:Iron-deficiency anaemia and its effect on worker productivity and activity patterns. 53 61

Using a new apparatus which enables us to measure in a continual manner the visual acuity for any distance; we have found considerable changes in the acuity between 24 metres and 10 centimetres. A drop in the visual acuity was found at the near vision. From dioptric and non-dioptric factors, we have infered our interpretation, which touches the question of visual fatigue and near vision.
J Fr Ophtalmol 1979 Dec
PMID:[The drop of visual acuity with distance and visual fatigue (author's transl)]. 53 74

Hyperprolactinemia, hypogonadotropinism, and subnormal plasma testosterone were found in a 65-year-old patient who had an enlarged sella turcica, complained of fatigue, and addmitted to decreased sexual interest and potency. Selective nontotal tumorectomy followed by bromocriptine therapy resulted in normoprolactinemia, increased plasma testosterone, and "rejuvenation difficult to follow" according to his wife. This patient described his sexual status as comparable to that of age 24 when he fathered his only child. Both wife and husband attributed the changes to bromocriptine and requested discontinuation (wife) and continuation (husband) of the treatment; because of the clinical indications, treatment was continued. Legally, a medical certification of a normal state of health was required before divorce--and subsequent marriage to a young woman--were permitted.
Psychosom Med 1979 Dec
PMID:Divorce and remarriage in a 65-year-old male following transphenoidal surgery and bromocriptine of hyperprolactinemic impotence: a dilemma. 54 26

In 64 male hypertonics the reaction and coordination functions and the condition were standardized and compared before and after a four weeks ambulatory treatment with diisopropylamine (3 times 200 mg a day) and reserpine (3 times 0.25 mg a day). The two medicaments achieved good blood pressure reducing effects. Since in reserpine the therapeutic effect later appeared, fatigue and need for sleep were more frequent and continuous, in older patients still after a treatment of four weeks right and temporary reactions decreased, wrong reaction increased and the aim accelerated, is concluded that here in particular in the behaviour of older people more frequently a longer lasting disturbance is probable.
Z Gesamte Inn Med 1979 Dec 01
PMID:[Reaction performance, motor coordination performance and findings in hypertensive patients under diisopropylamine and reserpine therapy]. 55 Jun 21

Reported here are four fractured femoral components from a consecutive series of 200 total hip reconstructions. All four had been placed in patients who weighed ninety-one kilograms or more and who were more than 1.8 meters tall. In each patient, roentgenograms made prior to the time of failure of the prosthesis revealed roentgenographic lucency, which was interpreted as cement failure. Metallurgical examination revealed fatigue failure and some abnormality in each prosthetic stem. Review of all 200 total hip replacements suggested that there was failure to position the prosthesis in strong valgus in there four hips and in thirty others. In the four failures, the contributing influences of large size of patients, inadequate valgus positioning of the prosthesis, inadequate support by cement, and metallurgical inadequacies of the prosthesis used are discussed.
J Bone Joint Surg Am 1977 Dec
PMID:Femoral stem failure in total hip replacement. 59 33

The response to prolonged antigen exposure and the potentiation of airway resistance increase to ACH challenge, after this exposure, were studied on sixteen boxer dogs. One group of animals presented fatigue to A.E. after 3 hours of exposure. This group developed an increased response to ACH aerosol after fatigue to antigen was present. In a second group of dogs, absence of fatigue during prolonged exposure to allergen was observed. A growing tendency of Edyn (as an index of airway resistance) was observed after 5 hours of exposure. The therapeutical influence of bilateral vagus blockade was tested in these last animals. Blockade of nervus vagus released airway obstruction during prolonged allergen exposure and no bronchoconstriction was observed after ACH challenge during blockade.
Res Exp Med (Berl) 1977 Dec 15
PMID:Fatigue of airway obstruction during long-term exposure to allergen aerosol. 59 97

Using observation in a number of patients with severe closed head injuries followed by prolonged coma and of which three are reported in detail, the authors present an analysis of the resulting psychiatric problems. After a brief review of the literature they suggest a central psychopathological "core" common to such head injuries beneath their seemingly diverse symptomatology. This "core" seems to be built up around the following disturbances: 1) Memory disorders; 2) Perceptual problems and difficulties with the association of ideas; 3) Excessive tiredness and concomitant reduction in the powers of concentration.
Ann Med Psychol (Paris) 1977 Dec
PMID:[Severe mental disorders after prolonged post-traumatic coma]. 61 Apr 93


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